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Mass General Research Institute

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Research Institute by the Numbers

Massachusetts General Hospital operates the largest hospital-based research program in the United States.

Massachusetts General Hospital operates the largest hospital-based research program in the United States. Here are some facts and figures about our research efforts.

With a budget of nearly  $1.2 billion  in 2021, Mass General is home to the largest hospital-based research enterprise in the United State. Mass General ranks 1 st among independent hospitals in the amount of annual funding received from NIH, and 8 th among all institutions.

Research at Mass General takes place in 30 departments, centers and institutes across the hospital. The Department of Medicine has the largest research portfolio at 20% of the total. We also have significant research programs taking place in our Thematic Research Centers (14%), the Mass General Cancer Center (10%), Neurology (12%), Radiology (11%), Surgery (5%) and Psychiatry (5%) and many others.

The research community includes more than 9,500 people and covers 1.3M square feet of research space in Boston, Cambridge and Charlestown. We have 2,000 principal investigators and there are 1,500 postdoctoral fellows and 800 graduate students training in research at Mass General at any given time. Over one-third of the 3,000 physicians at Mass General are also conducting research.

To date, more than 124,000 patients have consented to have their blood samples and health histories added to the Mass General Brigham Biobank , so we can learn more about the genetic basis of disease

The Office of the Scientific Director has established the Mass General Research Institute Blog to promote the work of investigators at Massachusetts General Hospital.

Since the inception of the  MGH Research Scholars program in 2011, a total of 75  Mass General investigators have received crucial unrestricted funding ($100,000 per year for five years) to support the game-changing ideas that are too early or unproven for traditional forms of funding.

Licensing Activity 130 133 198 197 145
Material Transfer Agreements 1067 1360 1374 1537 1256
New Disclosures 365 311 366 355 384
IP Applications 910 1091 1643 1593 1483
Issued Patents 339 359 356 629 484
Royalty and Licensing Outcome $77M $87.7M $94.6M $298M $142.9M

Check out the Mass General Research Institute blog

Bench Press highlights the groundbreaking research and boundary-pushing scientists working to improve human health and fight disease.

Top-ranked hospital in the U.S.

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The results are in: Mayo Clinic has more #1 rankings than any other hospital in the nation.

U.s. news & world report 2024-2025, specialty rankings.

Mayo Clinic is top-ranked in more specialties than any other hospital and has been recognized as an Honor Roll member according to U.S. News & World Report's 2024-2025 "Best Hospitals" rankings.

  • 1st Diabetes & Endocrinology
  • 1st Gastroenterology (GI) & GI Surgery
  • 1st Pulmonology & Lung Surgery (Tie)
  • 2nd Orthopedics
  • 2nd Neurology & Neurosurgery
  • 3rd Cardiology, Heart & Vascular Surgery
  • 3rd Obstetrics & Gynecology
  • 4th Ear, Nose & Throat
  • 4th Geriatrics
  • 5th Rheumatology
  • 6th Urology
  • 10th Rehabilitation

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Breakthroughs don’t happen unless you make them

We are changing the very definition of possible, and we're doing it right here, right now. Meet the physicians and teams united by an unrelenting purpose to change the future of healthcare, forever.

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From research to reality, faster

Mayo Clinic patients are often the first to benefit from our research. Right now, our doctors are working on more than 12,000 clinical studies, researching new treatments and therapies for the world’s most challenging and complex medical issues.

Mayo Clinic is honored to once again lead in more specialties than any other hospital. This recognition affirms our commitment to healthcare excellence as we continue to globally transform healthcare for people everywhere. Gianrico Farrugia, M.D. Mayo Clinic's president and CEO

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Phoenix/Scottsdale, Arizona

Mayo Clinic in Arizona is the No. 1 hospital in Arizona for the 12th consecutive year.

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Mayo Clinic in Florida is the No. 1 hospital in Florida.

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Rochester, Minnesota

Mayo Clinic in Minnesota is the No. 1 hospital in Minnesota and top-ranked in 13 specialties.

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Your donation can make a difference in the future of healthcare. Give now to support Mayo Clinic's research.

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Top hospitals for clinical research in the US

06-Aug-2019 - Last updated on 06-Aug-2019 at 14:20 GMT

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Dr. Irfan Khan, CEO of Circuit Clinical – the company behind TrialScout – said the award was established to recognize the clinical research programs “driving American health care forward.” ​

Among those hospitals recognized include Intermountain Medical Center, St. David’s Medical Center, Hospital of the University of Pennsylvania, Cleveland Clinic – Main Campus, Duke University Hospital at Duke University Medical Campus and Mayo-Clinic – Rochester.

“Hospitals are selected based on their exceptional performance in patient experience, proven expertise in clinical research, quality of care, and superior clinical research facilities,” ​ Khan told us.

This criteria was based on a composite score generated from TrialScout’s clinical research global dataset, which collates data from all active US clinical research institutions and links to publicly available datasets as well as real-time patient feedback.

Final scores were calculated using the company’s proprietary algorithm and, as such, exact rankings are not identified, as it is of Circuit Clinical’s intellectual property.

Khan described TrialScout as the first-ever ratings and reviews platform for patients considering or already participating in clinical research. The platform also provides peer-to-peer decision support and education “in a manner that will only expand in the year ahead,” ​ he added.

“When combined with TrialScout’s analytics platform, this gives research sites the ability to better understand their own strengths and weaknesses. Especially intangibles such as in-office experience and atmosphere,” ​he added.

"We are now at the beginning of the era of patient experience in clinical trials,” ​ Khan said. "Just as consumer voice amplified through platform technology has transformed the patient's position in health care selection – TrialScout looks to do the same for clinical trial participants." ​

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After private equity takes over hospitals, they are less able to care for patients, top medical researchers say

Nashoba Valley Medical Center.

After private-equity firms acquire hospitals , the facilities’ assets and resources diminish significantly, leaving the facilities less equipped to care for patients, according to a new study by physician researchers at the University of California at San Francisco, Harvard Medical School and the City University of New York’s Hunter College.

Published Tuesday in the  Journal of the American Medical Association,  the research highlights a pattern of asset stripping at health care facilities purchased by private-equity firms, its researchers said, and is the first study to analyze the activity nationwide. 

“It’s a very striking finding and should change the way people think about private equity in hospitals,” said Dr. Stephanie  Woolhandler , a distinguished professor of public health at Hunter, part of CUNY, and one of seven authors of the study. “The PE firms say, ‘We bring new capital into hospitals.’ It turns out that’s not quite true.”

Assets studied in the research consist of land, buildings, major hospital equipment and information technology. The study found that during the two years after a private-equity acquisition, total capital assets at private equity-acquired hospitals declined by 15% on average while assets rose by an average of 9% at other hospitals. That makes for a net difference of 24%, the researchers found, equivalent to a loss of $28 million in total assets per hospital.The research studied 156 hospitals acquired by private-equity firms from 2010 to 2019 comparing them with 1,560 hospitals of similar size in similar communities that were not bought by private equity. The pattern of diminished assets persisted and widened five years after acquisition, the study reported.

Depleted assets translate to a reduced level of care, Woolhandler told NBC News, noting that equipment, buildings and technology are resources needed for patient care. “There are real dangers to the health care that people get if you deplete all the capital from a hospital,” she added.

Private-equity firms borrow money to buy companies that they hope to sell in a few years at a profit. Independent academic research shows that such leveraged buyouts result in far more bankruptcies than acquisitions that do not use so much debt and the deals can result in significant job losses for rank-and-file workers.Health care has been a primary focus of private-equity purchases in recent years, with over $500 billion invested in the industry by firms such as Apollo Global Management, The Blackstone Group, The Carlyle Group and KKR. The  American Investment Council , the industry lobbying group, says private equity improves health care. 

But increased patient falls and infections follow private-equity takeovers of hospitals, recent research shows, and residents of nursing homes owned by private-equity firms experience 10% greater mortality rates than those owned by other types of entities.

“Previous studies have found that patients are endangered and costs increase in the wake of private-equity acquisitions,” said Dr. Elizabeth Schrier, a resident physician at the University of California, San Francisco, and a lead author of the new research.

The report on asset-stripping in private equity-owned hospitals comes amid the collapse of Steward Health Care, a hospital chain recently owned by private equity that filed for bankruptcy in May, leaving patients and workers at 31 facilities adrift. Last  week , the Senate’s Health, Education, Labor and Pensions committee announced an investigation into the Steward crisis. 

Until 2020, Steward was owned by Cerberus Capital, a private-equity firm led by Steve Feinberg. In 2010, Cerberus bought a nonprofit chain known as Caritas Christi Health Care for around $250 million. The firm and its investor partners reaped an $800 million profit when it divested a decade later.

Along the way, Steward sold the land under its hospitals, generating a gain for investors but increasing the company’s costs significantly.

A Cerberus spokesman said in a  statement that it’s unfair and incorrect to characterize the Steward land sale as “looting” the company, as Sens. Ed Markey and Elizabeth Warren, both Massachusetts Democrats, have done. “During our nearly 11-year ownership of Steward, we supported the revitalization of failing community hospitals into a leading healthcare system,” the statement continued. “Cerberus’ long-term investment made it possible for Steward to continue to serve its communities, employ tens of thousands of professionals, and positively impact millions of patients’ lives.”

Amid rising numbers of health care takeovers by private equity, at least 10 states are ramping up  scrutiny  on the transactions to prevent patient harm, such as rising health care costs or the effects of monopolization. On July 1, Indiana began requiring that private-equity partnerships proposing transactions with health care companies valued at $10 million or more to notify the state’s attorney general 90 days before the proposed deal. While approval of the transaction is not mandatory, the attorney general can analyze antitrust concerns or issue a civil investigative demand for more information.

California, Connecticut, Illinois and Nevada are among the other states enacting new laws bringing scrutiny to private equity’s health care acquisitions.

Health care is not the only industry in which some private-equity owners have stripped companies’ assets. The Red Lobster restaurant chain  failed  in part because its private-equity owner sold off the company’s prime real estate, generating gains for itself. Meanwhile, Red Lobster had to pay rent on the properties, raising its costs and ultimately hobbling its operations.

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Gretchen Morgenson is the senior financial reporter for the NBC News Investigative Unit. A former stockbroker, she won the Pulitzer Prize in 2002 for her "trenchant and incisive" reporting on Wall Street.

  • Top Medical Research Centers in the US

National Institutes of Health – Popularly known as NIH is an agency of the United States Department of Health and Human Services and is the primary agency of the United States government responsible for biomedical and health-related research.

Johns Hopkins – The Johns Hopkins University School of Medicine, located in Baltimore, Maryland (USA), in addition to operating a major medical school, operates the Johns Hopkins Hospital, which consists of both a teaching hospital and biomedical research facility.

Mayo Clinic – Mayo Clinic is an internationally recognized non-profit organization in the field of medical care, research and education . Mayo clinic is headquartered in Rochester, Minnesota.

My Canadian Pharmacy discovers and develops novel therapeutics to treat a variety of indications, including specific diseases of the nervous system corresponding to problems of the brain-gut axis, pain/inflammation, erectile issues, autoimmune issues. Pharmos corp is seeking a partnership with one other pharmaceutical company to additional develop this promising compound for IBS.

Massachusetts General Hospital – MGH is one of the largest teaching hospital of Harvard Medical School and a biomedical research facility located in the West End neighborhood of Boston, Massachusetts. It is one of the oldest and largest hospital in New England.

Texas Medical Center – The Texas Medical Center is the largest medical center in the world with one of the highest densities of clinical facilities for patient care, basic science, and translational research.[1][2][3] Located in Greater Houston, the center contains 54 medicine-related institutions, including 21 hospitals and eight specialty institutions, eight academic and research institutions, four medical schools, six nursing schools, and schools of dentistry, public health, pharmacy, and other health-related practices.

Cleveland Clinic – The Cleveland Clinic is a multispecialty academic medical center located in Cleveland, Ohio. Currently regarded as one of the top hospitals in the United States,[8] the Cleveland Clinic was established in 1921 by four physicians for the purpose of providing patient care, research, and medical education in an ideal medical setting. One of the largest private medical centers in the world,

NewYork-Presbyterian Hospital – NewYork-Presbyterian Hospital is a prominent university hospital system in New York City, composed of two medical centers, Columbia University Medical Center and the Cornell University Weill Medical Center.

University of Pennsylvania Health System – The University of Pennsylvania Health System is a diverse research and clinical care organization in Philadelphia, Pennsylvania. Founded in 1993, it currently operates under the direction and auspices of Penn Medicine, a division of the University of Pennsylvania

University of Pittsburgh Medical Center – The University of Pittsburgh Medical Center (UPMC) is headquartered in Pittsburgh, Pennsylvania and is closely affiliated with its academic partner, the University of Pittsburgh and its six schools of the health sciences

UCSF Medical Center – The UCSF Medical Center is a world-renowned teaching hospital and center of biomedical research located in San Francisco, California, with campuses in Parnassus Heights, Lower Pacific Heights and Mission Bay. It is one of the leading hospitals in the United States and with the UCSF School of Medicine has been the site of various breakthroughs in all specialties of medicine, including the discovery of oncogenes, prions as the etiologic agents of transmissible spongiform encephalopathies, first in-utero fetal surgery and more

Ronald Reagan UCLA Medical Center – The Ronald Reagan UCLA Medical Center is a hospital located on the campus of the University of California, Los Angeles in Los Angeles, California. UCLA Medical Center has research centers covering nearly all major specialties of medicine as well as dentistry and ophthalmology, and is the primary teaching hospital for the David Geffen School of Medicine at UCLA.

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NEOMED Hearing Collaboration Highlighted in 2024 State of Research Address

August 06, 2024

By Alejandro Rivas, MD , Viral Tejani, AuD, PhD , and UH

Innovations in Ear, Nose & Throat | Summer 2024

In his  2024 State of University Hospitals Research Address ,  Daniel I. Simon, MD ,  President of Academic & External Affairs and Chief Scientific Officer, highlighted the burgeoning hearing research partnership between University Hospitals and Northeast Ohio Medical University (NEOMED).

Alejandro Rivas, MD

It is a collaboration that unites the region’s expertise in peripheral and central hearing loss, fostering cohesion between the two research groups. Dr. Simon underscored how the symbiotic partnership is impacting both basic and clinical science and is significantly amplifying the efficacy of new research grants. 

“University Hospitals has a strong center for hearing sciences, led by Kumar Alagramam, PhD , that is conducting research primarily focused on the auditory pathway from the outer ear to the brainstem, whereas the NEOMED team focuses on everything that happens past the brainstem to the auditory cortex of the brain,” says Alejandro Rivas, MD , Division Chief of  Otology and Neurotology , Director of the UH Cochlear Implant Center and the Richard W. and Patricia R. Pogue Chair in Auditory Surgery and Hearing Sciences, University Hospitals. “By working together, we can maximize our research efforts to more fully understand the entire auditory pathway to better care for patients and unlock new potential for hearing restoration.”

Proposals Garner Funding

Participants recently held their first symposium and identified joint interests that sparked plans for further collaboration, plans that include the study of the cortex and central auditory pathway in animal models and the implications of hearing loss on children’s behavior. They presented current projects, and four proposals were awarded the opportunity for funding. Other proposals are in development. 

“The partnership brings together Northeast Ohio’s leaders in auditory research from both institutions and has become a wonderful mechanism to inspire inquisitive minds as we train UH and NEOMED students,” Dr. Rivas says. 

This summer, a group of medical students from NEOMED are participating in basic and clinical research initiatives under way at University Hospitals. “We have a strong clinical infrastructure and volume to offer,” says Viral Tejani, AuD, PhD , Senior Cochlear Implant Clinical Research Audiologist within the University Hospitals Ear, Nose & Throat Institute .

Dr. Tejani is mentoring a student analyzing data gathered through UH’s nationally renowned cochlear implant program. “She will be exposed to the clinical outcomes and some of the factors that are evolving within our cochlear implant patients,” he says. “Specifically, we are looking at how well we’re able to preserve some of the cellular and neural integrity within the auditory system with newer designs of cochlear implants and how patients are doing in terms of word-understanding outcomes, as well as some of the finer details about the electrical circuitry of the implant itself.” Two other NEOMED students are working with University Hospitals and School of Medicine researchers in basic science labs.

Partnering for Innovation

With a research focus on cochlear implant electrophysiology, Dr. Tejani is excited to share knowledge with an audiology faculty member at NEOMED. “The way you advance science and fill in missing links or research gaps is through partnerships,” he says. “This collaboration benefits both institutions by providing opportunities to faculty and students that drive innovation and ultimately help patients.”

The novel partnership is paving the way for the two institutions to bring together additional faculty scholars in other areas of otolaryngology. With one of the largest cochlear implant programs in the nation and a large ENT patient volume, including robust adult and pediatric otolaryngology clinics, University Hospitals offers an ample patient pool for future research endeavors. For example, a current NEOMED researcher is interested in ear infections and can benefit from tapping into University Hospitals’ large clinical caseload treating this condition.  

“We want to be recognized not only for our national and international collaborations but also for our regional ones,” Dr. Rivas says. “Hopefully, we will be able to extend these opportunities to colleagues and students in other areas of ENT and beyond.”

For more information about University Hospitals’ partnership with NEOMED and ongoing auditory research, contact Dr. Rivas at [email protected] or Dr. Tejani at [email protected] .

Contributing Experts:  Alejandro Rivas, MD Division Chief, Otology and Neurotology Director, Cochlear Implant Center University Hospitals Ear, Nose & Throat Institute Richard W. and Patricia R. Pogue Chair in Auditory Surgery and Hearing Sciences University Hospitals Professor Otolaryngology-Head and Neck Surgery Neurological Surgery Case Western Reserve University School of Medicine

Tags: Innovations in Ear Nose Throat Summer 2024 , Cochlear Implant , Research , Innovation

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Something big soon in India: Hindenburg hints at another report after Adani Group

Hindenburg research teases another big revelation in india, fuelling speculation after its explosive report on the adani group..

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Hinderburg Research says 'something big soon' in India.

  • Financial world is on high alert as Hindenburg hits new revelation
  • Previous report impacted Adani Group's market value
  • Sebi had issued notice against Hindenburg in June

Hindenburg Research, the US-based short seller known for its scathing report on the Adani Group in January 2023, has hinted at another revelation involving an Indian company.

On X (formerly Twitter), the firm said, “Something big soon India.”

However, the research firm has shared no additional details yet.

Hindenburg’s report on the Adani Group , released just before a major share sale by Adani Enterprises, had a massive impact, wiping out $86 billion in the conglomerate's market value.

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The short seller pointed out that Sebi’s notice conspicuously avoided naming Kotak Bank, despite its alleged involvement in offshore fund structures related to the Adani Group.

Hindenburg suggested that Sebi might be protecting powerful Indian businessmen from scrutiny.

The Sebi notice also disclosed connections between Hindenburg Research and New York hedge fund manager Mark Kingdon. It was revealed that Kingdon Capital, which held significant investments in Kotak Mahindra Investments Limited (KMIL), received an advance copy of Hindenburg’s Adani report.

This allowed the hedge fund to profit significantly by taking short positions in Adani Enterprises before the report’s release, yielding a profit of $22.25 million.

Kotak Mahindra Bank denied any involvement or knowledge of Kingdon’s activities, while Kingdon Capital defended its right to engage in research agreements that allow the use of reports before they are made public.

  • DOI: 10.17072/2218-1067-2022-1-49-57
  • Corpus ID: 249915637

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Trust in physicians and hospitals plummeted since the COVID pandemic, Northeastern research says

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A nurse holding the hands of a patient.

A grateful public called doctors health care heroes and collected personal protective equipment and pizzas for them during the early, deadliest days of the COVID-19 pandemic.

But nearly four years later, public trust in physicians and hospitals plummeted, going from 71.5% in April 2020 to 40.1% in January 2024, according to a 50-state survey of U.S. adults led by Northeastern University’s distinguished professor of political science and computer sciences.

“It is obviously a very, very sizable decline,” says David Lazer , whose research was published in JAMA Open Access , a peer-reviewed medical journal.

And it’s one with public health repercussions, since individuals with lower levels of trust were less likely to get vaccinated against COVID or seasonal influenza, he says.

“It is striking that we saw distrust predicted future vaccination status,” Lazer says. “While we can’t be sure that this is a causal relationship, it is consistent with the possibility that distrust is a factor in lower vaccination rates.”

David Lazer standing in the doorway of a building.

The study’s authors say “the pandemic may have represented a turning point in trust, with a profession previously seen as trustworthy increasingly subject to doubt.”

The distrust was distributed across all socio-economic groups in the 50-state survey borne of the COVID States Project, which has transformed into the Civic Health and Institutions Project , a 50 States Survey (CHIP50).

But it was particularly acute among people who had lower education and lower income, are Black, female or live in a rural area. The associations persisted even after controlling for partisanship, the report says.

The survey consisted of online interviews with 443,455 individuals 18 and older in all 50 states, with pains being taken to represent populations in terms of race, ethnicity, gender and age.

The wave of 24 surveys starting April 1, 2020, and ending Jan. 23, 2024, asked questions such as “How much do you trust the following people and organizations to do what is right” with possible answers ranging from “a lot, some, not too much or not at all.”

In waves prior to August 2022, researchers asked a variant of the question, querying respondents about  “How much do you trust the following people and organizations to do the right thing to handle the current coronavirus (COVID-19) outbreak?”

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 “We asked them if they were vaccinated, and about trust, and found that those two things were correlated,” Lazer says.

“We also looked at whether expression of distrust predicted future vaccine status, as measured by self report on the survey, and it did.”

The paper did not specifically ask about people’s opinions about masking and vaccination mandates, Lazer says, “but, yes, trust was strongly related to those things.”

In response to several open-ended questions, people with lower levels of trust commented that “doctors were just in it for the money” and communicated problems with billing issues, he says.

The levels of distrust may come as a surprise because doctors traditionally enjoy a great degree of public confidence.

Lazer and his co-authors say a 2022 survey reported that U.S. adults had “greater trust in physicians and nurses than in any other institution, including the Centers for Disease Control and Prevention.”

The early results may have represented an inflation of people’s esteem for the medical profession at a time when hospital emergency departments were besieged by COVID-19 cases, Lazer says.

The survey results are concerning to the researchers, who say most adults see a physician regularly and rely on their health care provider for information on everything from diet and exercise and smoking cessation to seatbelt use and firearm safety.

The politicization of the COVID-19 epidemic helped fracture the connection between the public and traditional sources of health information, Lazer says.

“If you don’t trust the establishment, if you don’t trust institutions, you’re more likely to go to Facebook groups who are making strange recommendations regarding health-related behaviors,” he says.

Some of the distrust has deeper roots, particularly among marginalized groups including women and people of color who may doubt the medical system is representing their interests, Lazer says.

“If people don’t see individuals like themselves in medicine, they may be less trusting of medicine,” he says.

In the short run, restoring trust in public health could mean working with trusted community partners to communicate health practices based on best evidence, including vaccination, Lazer says.

“Then there are the longer-term solutions, which is to diversify medicine, diversify science,” he says. “It’s never too late.”

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Health Care Access & Coverage

How For-Profit Hospitals Billed More Aggressively Than Nonprofits For Medicare Outlier Payments: A Case Study From the Early 2000s

For-profits were also likelier to spend new revenue on executive pay and share buybacks, atul gupta, phd.

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Woman in scrubs holding piggy bank.

American hospitals account for the largest nonprofit sector in the United States, but while most U.S. hospitals are nonprofit, a significant portion are for-profit. Policymakers and researchers long have questioned whether nonprofit hospitals behave differently than for-profit hospitals. In a recently released National Bureau of Economic Research working paper that examines this question, we made use of a now-resolved loophole in Medicare payment policy to understand how nonprofit and for-profit hospitals exploited this loophole, and what they did with the resulting financial windfall.

What was the loophole? Medicare used hospitals’ list prices (also called “charges”) to determine how much hospitals should get in “outlier payments” — which reimbursed hospitals beyond Medicare’s usual fixed-price contract for providing especially resource-intensive care. Because the Centers for Medicare and Medicaid Services could not observe the true costs of this treatment, they relied on those list prices, giving hospitals the opportunity to inflate them.

We used a novel approach to find hospitals that gamed the system with inflated charges for outlier payments during this time period and identified 180 such hospitals. The gain for these hospitals was substantial, resulting in a windfall of $3 billion in Medicare payments and $12 billion when including all insurers’ payments over this time period. (For perspective, consider that the total spending on the Women, Infants and Children’s (WIC) program in 2022 was $6 billion.)

Both for-profit and nonprofit hospitals took advantage of the loophole. But we found that the type of ownership was highly predictive of gaming, with the for-profit hospitals more likely to exploit the loophole than the nonprofit hospitals. The for-profit hospitals also were more likely to pocket the money rather than reinvesting it in patient care.

Hospitals That Gamed the System Derived Direct and Indirect Revenue Benefits

We found that weaknesses in government contracts can produce ripple or “spillover” effects that may far exceed in magnitude the direct revenue increases, based on our comparison of the revenue trends of the “gamer” hospitals versus those of a matched set of hospitals that did not inflate list prices for outlier payments. As our analysis showed, the impact of the loophole extended beyond the increased payments from Medicare to include increased payments from private insurance too.

This spillover — adding up to $12 billion — perhaps resulted from private insurers using similar payment designs and negotiating contracts based on list prices. The higher spending by private insurers, which then likely was passed on to employers in the form of higher insurance premiums, greater cost sharing for employees, and even salary decreases, highlights the importance of considering spillover effects when determining whether investments in oversight or enforcement actions are justified.    

Nonprofit Hospitals More Likely to Use Extra Money on Operating Costs

It is unclear exactly why the for-profit hospitals were more likely to take advantage of the Medicare outlier payment loophole. We hypothesize that managers of for-profit hospitals had more incentive to maximize revenue since they could distribute profits to themselves. We also hypothesize that managers who joined nonprofits versus for-profits differed in their financial motivation.      

What is clear, though, is that the nonprofit and for-profit gamers spent the extra revenue in different ways, consistent with predictions from organizational theory. Nonprofits directed about 75% of the gaming revenue to operating costs, with no increase in compensation for senior executives. We detected a modest but statistically significant improvement in the mortality rate at these nonprofit hospitals.

In contrast, for-profit hospitals transferred all of the excess revenue off their balance sheets, with no effect on patient care. For the largest and most important gamer, the Tenet Corporation, we showed that the excess revenue dramatically increased compensation for its highest-paid executives at the peak of gaming. Compensation more than doubled, from $6 million to $12 million and stock options ballooned to $92.5 million.

The system also engaged in stock buybacks, which resulted in nearly a billion dollars transferred to shareholders. In the case of for-profit hospital systems, this evidence strongly suggests that investing in more stringent oversight is likely to carry high social value.

Loopholes Will be Exploited and For-Profit Hospitals May Warrant Greater Scrutiny

Although the findings look back to a loophole closed two decades ago, they are particularly salient now. According to the US GAO, Medicaid and Medicare made more than $100 billion in improper payments in 2023.

The issue of improper payments has taken on additional policy significance in the aftermath of large payouts to hospitals for care related to the COVID-19 pandemic. Congress authorized nearly $200 billion in pandemic-related emergency assistance for healthcare providers.

There are concerns that some hospitals and other entities abused this and other COVID-era relief programs. The appropriate policy responses — in response to such “gaming” — depend on how the marginal dollar of excess revenue ends up being allocated.

For example, if hospitals direct excess revenue to patient care, policymakers may have less to fear from loopholes. However, if the excess revenue has limited benefits for patients and workers, it would support devoting greater resources to contract design and payment oversight.

The working paper, “Turbocharging Profits? Contract Gaming and Revenue Allocation in Healthcare,” was published June 2024 by the National Bureau of Economic Research and authored by Atul Gupta , Ambar La Forgia, and Adam Sacarny.

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Assistant Professor, Health Care Management, Wharton School

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To Help People on Medicare and Medicaid, We Must Pay Providers for Integrating Care

People Enrolled in Both Medicare and Medicaid are Getting Much Needed Attention, An LDI Conference Shows

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Advancing Equity In Kidney Transplantation Through The Increasing Organ Transplant Access Model

LDI Fellows Discuss Equity in Health Affairs Forefront

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A Federal Court Ruling Puts Free Preventive Care at Risk

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Large Animal Lover at Heart

Photo of a person posing with a brown horse outside in a holding pen with a red barn in the background.

Where are you from? I spent my childhood and teenage years in the Capital of Belgium, Brussels.

Share your academic journey to becoming a veterinarian .  I started my Bachelor's in Brussels before doing my Master's in Veterinary Medicine at the University of Liège, Belgium. I graduated in 2016, worked first in Belgium, then traveled to gain more experience by learning at the highest level possible.

How did you come to Cummings School of Veterinary Medicine?    The Invisible Hand of the Residency Match was decided, and I'm happy with the result. New England is quite close to my home country in terms of culture and patience, but it also has the added benefit of seeing the sun much more regularly!

What has surprised you during your tenure here ?  Patience. We have incredible mentors who are incredibly patient with sometimes reluctant horses. They take their time to explain procedures in detail to both owners while making the students part of the caregiving team at each step.

What do you hope to do after completing your time at Cummings School ?  Go on saving large animals with the high level of care that Tufts thrives to apply.

Share an experience from your time at Cummings School that stands out to you?  Our incredible nurses (besides being the best support we could hope for) always strive to go above and beyond. They consistently remind us that we don't need to take ourselves seriously while doing serious work. Our patients are their canvas, and bandages are an excuse for creativity. Sometimes, bringing old kids' clothing, you can't help laughing at an obese goat in a cartoon pajama.

What brings you joy professionally?  Solving a lameness that has been a mystery for months. Working with multiple teams. Planning a surgery after visualizing a fracture with a radiologist ultrasonographer and then discussing the pain relief plan with the anesthesiologist. Giving the first hand full of grass to a post-op colic. Seeing the excitement and fear in a student's eyes when you guide them through a procedure and the happiness when it is a success.

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'Something big soon India,' Hindenburg hints at another major revelation after Adani disclosure

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Hindenburg Research, the US-based short seller, hinted at another major disclosure related to India on Saturday. On Saturday, the firm posted on X stating, "Something big soon India." This comes after their explosive report last January, which scrutinised the Adani Group just before a planned share sale by Adani Enterprises.

The release of Hindenburg's report led to a sharp decline in Adani Enterprises Ltd's (AEL) stock price, which plummeted by 59% within a month. The January 2023 report had a profound impact, wiping out $86 billion from the market value of Adani Group stocks and sparking a substantial sell-off of its overseas bonds.

Hindenburg accused the conglomerate of engaging in what it termed "the largest con in corporate history," leading to a steep decline in the value of Adani's listed companies.

Something big soon India — Hindenburg Research (@HindenburgRes) August 10, 2024

Mewanwhile, the Securities and Exchange Board of India (SEBI) recently unveiled new details in the ongoing Adani-Hindenburg saga, particularly concerning Hindenburg's ties with New York hedge fund manager Mark Kingdon.

According to SEBI, Hindenburg provided Kingdon with an advance copy of its report on Adani nearly two months before its public release, enabling Kingdon to profit from strategic trades. In a comprehensive 46-page show cause notice, SEBI outlined a "Research Agreement" between Hindenburg and Kingdon Capital Management, established in May 2021.

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Health | Hoag recruits top doctor in hospital’s push…

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Health | hoag recruits top doctor in hospital’s push to become research leader, the health care provider is investing $1 billion in its irvine campus and will soon open a new digestive health and cancer center..

big research hospitals

Short of all sorts of supplies, he recalls using fishnets for sutures, fishhooks for needles and, generally, rigging up a whole menagerie of equipment with whatever his team had on hand.

When he returned to Brown University to finish medical school, his Ivy League colleagues thought he was mad, he said. “I was willing to experiment with materials that most of my peers wouldn’t touch.”

Some 40 years later, Chang’s patents are used in medical offices around the world to treat patients for gastrointestinal health and improve pre-cancer diagnosis and therapy.

After a distinguished career at UC Irvine where he launched the university’s comprehensive digestive disease center and was chief of the medical school’s division of gastroenterology, Chang accepted a new challenge this summer at Hoag.

His vision, backed by a substantial investment from the healthcare provider, is to launch Orange County’s largest digestive health institute in the the next two years, transform the community hospital into a research leader and — eventually — eradicate Orange County of esophageal and colon cancer.

Within the next two years, t hanks to a recent $1 billion investment , Hoag will greatly expand its Irvine medical center with six new buildings, including new centers for women’s health and surgical innovation and Chang’s institute for digestive health and cancer treatment.

Looking at the construction underway, Chang and Hoag President and CEO Robert Braithwaite said the revitalization of the medical center will push the community healthcare system to become more like a research institute that also provides top-notch care.

Dr. Kenneth Chang, executive medical director of the Digestive Health Institute, left, and Robert T. Braithwaite, president and CEO of Hoag Hospital, stand at a model showing the expansion at Hoag Hospital in Irvine, CA on Wednesday, July 31, 2024. (Photo by Paul Bersebach, Orange County Register/SCNG)

Braithwaite said he aims to shape Hoag in the model of the Mayo Clinic — not itself a university, but still a renowned medical leader in training fellows and conducting cutting-edge research.

Following this round of construction, for example, Braithwaite plans to construct another Irvine campus building where corporate biotech innovators will work hand-in-hand with Hoag doctors to put new technology on the fast track from the research bench to the operating room, he said.

Hoag’s determination to grow in Irvine spurred from community need, Braithwaite said. Around 2017, Hoag’s Irvine hospital was frequently reaching 100% capacity. It was a clear sign they needed to expand.

But Hoag wanted to “grow different,” he said, beckoning a phrase that harnesses the community hospital’s Apple-sized ambitions.

Hoag hired 10 architectural firms to come up with designs for a remodeled Irvine medical campus, which originally opened as a traditional hospital tower under another operator in the 1980s and changed hands a couple of times before Hoag moved in about 15 years ago.

“I told the architects we want you to use your best thinking and best research in healthcare to bring us a new design,” Braithwaite said.

Two of the firms came up with what Hoag’s calling an “institute model.”

Gone are the days of cardiology on floor 4, pulmonary on floor 5, GI on floor 6, and so on, Braithwaite said.

The new model is about synergy, not separation.

“We want to create a flow of clinicians and experts in one area,” he said. “This is not a general approach, but it’s about giving people what they want and deserve: expertise and quality.”

His idea is that the physical design of the buildings will, like a university, encourage innovation between physicians, endoscopists and others as they pass each other in the halls.

Hoag’s Dr. Elizabeth Raskin, left, CEO Robert Braithwaite, Dr. Allyson...

Hoag’s Dr. Elizabeth Raskin, left, CEO Robert Braithwaite, Dr. Allyson Brooks and Dr. Burt Eisenberg hold an artist’s rendering of the health center’s expansion plans in Irvine in 2022. The expansion will include six new buildings, with specialized institutes in women’s health, cancer and digestive illnesses.(Photo by Mindy Schauer, Orange County Register/SCNG)

A rendering of what the Women’s Health Institute will look...

A rendering of what the Women’s Health Institute will look like on Hoag’s new Irvine campus. It and two other medical institutes are expected to open by 2025. (Rendering courtesy of Hoag Hospital)

Dr. Kenneth Chang, Executive Medical Director of the Digestive Health...

Dr. Kenneth Chang, Executive Medical Director of the Digestive Health Institute, speaks about his role at Hoag Hospital in Irvine, CA on Wednesday, July 31, 2024. (Photo by Paul Bersebach, Orange County Register/SCNG)

That’s where Chang comes in. With his 30 years of experience at UCI, Braithwaite believes Chang is the leader who can shepherd Hoag into a new era of cancer research and care.

One way Chang says he plans to tackle cancer is by putting Hoag at the forefront of using novel, less invasive technologies. Soon, someone with inflammatory bowel disease, for example, might be screened with an endoscopic ultrasound instead of a colonoscopy, he said.

“Our goal is to treat life-altering conditions with less and less invasive techniques,” Chang said. “We’re miniaturizing the whole approach to cancer.”

The traditional approach to treating cancer, especially at the dawn of oncology in the 20th century, was notoriously invasive — think rounds and rounds of chemotherapy and life-threatening organ removals.

Chang wants to “miniaturize” everything about the cancer paradigm — the consequences, the risks, the procedures, the incidence.

“When we talk about cancer, where do things go awry? It’s at the cell level,” he said. The smallest common denominator of life. “Right now, when it comes to treatment, we wait for a cell to multiply a gazillion times and then it becomes a cancer,” he said. “If you have bad plumbing, you don’t wait for your house to flood. You fix the leak.”

But, he and Braithwaite say Hoag’s vision is not just about innovation. It’s about people.

“One of my guiding statements in my career is innovation fueled by compassion,” Chang said.

“There’s innovation fueled by money, prestige and power,” he added. “None of that is sustainable for me. But when you have innovation for a patient in critical condition in front of you, you’ll not accept ‘no’ for an answer. You’ll search your heart and soul for a solution.”

He reflects back on his missionary work 40 years ago. “If we didn’t have what we needed,” he said, “we would make it.”

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