COVID-19: What are the 4 phases of vaccine clinical trials?
Covid vaccines: How fast is progress around the world?
Covid-19 Vaccines vs. Infections
Covid vaccine tracker: How’s my country and the rest of the world doing
COMMENTS
Effectiveness of mRNA Covid-19 Vaccine among U.S. Health Care Personnel
To evaluate the effectiveness of mRNA vaccines in preventing Covid-19 among health care personnel in the United States, we conducted a multisite, test-negative case-control study involving ...
A case-case study on the effect of primary and booster immunization
KEYWORDS: COVID-19 vaccine, Ct value, case-case study, real-world study, booster immunization. Introduction. As of 21 February 2022, World Health Organization (WHO) data showed that there were nearly 500 million COVID-19 cases and over 6 million deaths reported globally . COVID-19 vaccines are an important means for preventing COVID-19 and its ...
Association Between mRNA Vaccination and COVID-19 Hospitalization and
This case-control study explores the association between vaccination with mRNA COVID-19 vaccines and hospitalization for COVID-19, and, among patients hospitalized with COVID-19, the association with progression to critical disease in adults from 18 US states.
Impact of vaccination on the COVID-19 pandemic in U.S. states
Study design. We collected state-level daily infection and hospitalization data in the U.S. from 12 October 2020 to 7 March 2021. Figure 1 shows a timeline of COVID-19 developments during this ...
Long-term effectiveness of COVID-19 vaccines against infections
In this rapid living systematic evidence synthesis and meta-analysis, we searched EMBASE and the US National Institutes of Health's iSearch COVID-19 Portfolio, supplemented by manual searches of COVID-19-specific sources, until Dec 1, 2022, for studies that reported vaccine effectiveness immediately and at least 112 days after a primary vaccine series or at least 84 days after a booster dose.
Effectiveness of COVID‐19 vaccines: findings from real world studies
Community‐based studies in five countries show consistent strong benefits from early rollouts of COVID‐19 vaccines. By the beginning of June 2021, almost 11% of the world's population had received at least one dose of a coronavirus disease 2019 (COVID‐19) vaccine. 1 This represents an extraordinary scientific and logistic achievement — in 18 months, researchers, manufacturers and ...
Safety & effectiveness of COVID-19 vaccines: A narrative review
Safety & effectiveness of COVID-19 vaccines: A narrative ...
Protection against SARS-CoV-2 after Covid-19 Vaccination and Previous
The population uptake of two doses of Covid-19 vaccines in the United Kingdom (in persons >12 years of age) as of February 2022 was 84.5%, 5 and it has now been more than 6 months since the second ...
Effectiveness of COVID-19 vaccination against COVID-19 specific and all
Effectiveness of COVID-19 vaccination against ...
Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
Discussion. A two-dose regimen of BNT162b2 (30 μg per dose, given 21 days apart) was found to be safe and 95% effective against Covid-19. The vaccine met both primary efficacy end points, with ...
Waning of vaccine effectiveness against moderate and severe covid-19
Objective To estimate the effectiveness of mRNA vaccines against moderate and severe covid-19 in adults by time since second, third, or fourth doses, and by age and immunocompromised status. Design Test negative case-control study. Setting Hospitals, emergency departments, and urgent care clinics in 10 US states, 17 January 2021 to 12 July 2022. Participants 893 461 adults (≥18 years ...
Evaluating COVID-19 vaccines in the real world
The effectiveness of the mRNA vaccines in preventing COVID-19 disease progression in 2021 set new expectations about the role of prevention interventions for the disease. Efficacy observed in the trials was more than 90%.1,2 The efficacy of other vaccines evaluated in large randomised trials, such as the Oxford-AstraZeneca (70%) and Sputnik V (91%) vaccines, have been criticised for elements ...
Public attitudes toward COVID-19 vaccination: The role of vaccine
While efficacious vaccines have been developed to inoculate against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; also known as COVID-19), public vaccine hesitancy could still ...
COVID-19 vaccine development: milestones, lessons and prospects
COVID-19 vaccine development: milestones, lessons and ...
Public health impact of covid-19 vaccines in the US: observational study
Objective To evaluate the impact of vaccine scale-up on population level covid-19 mortality and incidence in the United States. Design Observational study. Setting US county level case surveillance and vaccine administration data reported from 14 December 2020 to 18 December 2021. Participants Residents of 2558 counties from 48 US states. Main outcome measures The primary outcome was county ...
Study: Highlighting harms of skipping COVID vaccines more ...
rogerashford / iStock. The US Food and Drug Administration (FDA) today announced that it has granted emergency use authorization for Novavax's updated COVID-19 vaccine.. Approval of the protein-based vaccine comes about a week after the FDA green-lighted the two updated mRNA vaccines—made by Moderna and Pfizer-BioNTech—which target the KP.2 variant. . The Novavax vaccine targets JN.1, the ...
Vaccine Effectiveness Studies in the Field
As of June 19, 2021, Covid-19 vaccines are estimated to have prevented 7.2 million infections and 27,000 deaths in England alone. 12 Similarly, ... Brazil: a test-negative case-control study.
Comprehensive literature review on COVID-19 vaccines and role of SARS
Introduction. The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in over 192 million cases and 4.1 million deaths as of July 22, 2021. 1 This pandemic has brought along a massive burden in morbidity and mortality in the healthcare systems. Despite the implementation of stringent public health measures, there ...
Pfizer and BioNTech Conclude Phase 3 Study of COVID-19 Vaccine
Pfizer and BioNTech Conclude Phase 3 Study of COVID ...
Risk factors and disease profile of post-vaccination SARS-CoV-2
COVID-19 vaccines show excellent efficacy in clinical trials and effectiveness in real-world data, but some people still become infected with SARS-CoV-2 after vaccination. ... This prospective, community-based, nested, case-control study used self-reported data (eg, on demographics, geographical location, health risk factors, and COVID-19 test ...
The gut microbiota modifies antibody durability and booster responses
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are pivotal in combating coronavirus disease 2019 (COVID-19); however, the declining antibody titers postvaccination pose challenges for sustained protection and herd immunity. Although gut microbiome is reported to affect the early antibody response after vaccination, its impact on the longevity of vaccine ...
Evaluating the COVID-19 vaccination program in Japan, 2021 ...
Evaluating the COVID-19 vaccination program in Japan ...
Collaboration in times of crisis: A study on COVID-19 vaccine R&D
We identified 93 partnerships with ≥2 entities and 190 single entities developing COVID-19 vaccines registered by the WHO. Of the 81 partnerships we deductively analyzed, we found that 71 had a company partner. Further, we found that 46 (56.8%) were involved in " materials transfer" and 35 (43.2%) in " knowledge sharing".
Strategy for COVID-19 vaccination in India: the country with the second
Strategy for COVID-19 vaccination in India: the country with ...
New study provides insight to why COVID vaccines hit some harder than
Students receiving the COVID 19 vaccine at Hawley Armory on April 8, 2021. The rollout of the vaccines across the state in the spring helped set up a return to a more familiar university experience.
Risk of autoimmune diseases following COVID-19 and the potential
Risk of autoimmune diseases following COVID-19 and ...
Effect of Vaccination on Household Transmission of SARS-CoV-2 in
Association between COVID-19 Vaccination and SARS-CoV-2 Infection among Household Contacts of Infected Individuals: A Prospective Household Study in England, Vaccines, 12, 2, (113), (2024). https ...
Impact of the COVID-19 pandemic on bike-sharing uses in two French
Feedback from COVID-19 suggests that vaccination alone is inefficient to eradicate such a virus and a fine understanding of the parameters of its diffusion is a key factor ... The link between bike sharing and subway use during the Covid-19 pandemic: the case-study of New York's Citi Bike. Transp. Res. Interdiscip. Perspect. 6, 100166 (2020)
News
In addition, Cabinet has now also removed COVID-19 from the list of quarantinable infectious diseases. News article ; Notifiable diseases COVID-19 Public health New Zealand's first health strategy for people with rare disorders. Publication date: 25 July 2024. The Ministry of Health has published New Zealand's first dedicated, health system ...
COVID-19 diagnosis, vaccination during pregnancy, and adverse pregnancy
These studies showed that pregnant women diagnosed with COVID-19 are more likely to experience pre-eclampsia, 8, 12, 13, 25 gestational hypertension 9 and preterm birth. 7, 8, 12-14, 26 Whilst a meta-analysis of 117,552 vaccinated pregnant women underscores COVID-19 vaccine efficacy in preventing infection and hospitalization, 27, 28 few ...
IMAGES
COMMENTS
To evaluate the effectiveness of mRNA vaccines in preventing Covid-19 among health care personnel in the United States, we conducted a multisite, test-negative case-control study involving ...
KEYWORDS: COVID-19 vaccine, Ct value, case-case study, real-world study, booster immunization. Introduction. As of 21 February 2022, World Health Organization (WHO) data showed that there were nearly 500 million COVID-19 cases and over 6 million deaths reported globally . COVID-19 vaccines are an important means for preventing COVID-19 and its ...
This case-control study explores the association between vaccination with mRNA COVID-19 vaccines and hospitalization for COVID-19, and, among patients hospitalized with COVID-19, the association with progression to critical disease in adults from 18 US states.
Study design. We collected state-level daily infection and hospitalization data in the U.S. from 12 October 2020 to 7 March 2021. Figure 1 shows a timeline of COVID-19 developments during this ...
In this rapid living systematic evidence synthesis and meta-analysis, we searched EMBASE and the US National Institutes of Health's iSearch COVID-19 Portfolio, supplemented by manual searches of COVID-19-specific sources, until Dec 1, 2022, for studies that reported vaccine effectiveness immediately and at least 112 days after a primary vaccine series or at least 84 days after a booster dose.
Community‐based studies in five countries show consistent strong benefits from early rollouts of COVID‐19 vaccines. By the beginning of June 2021, almost 11% of the world's population had received at least one dose of a coronavirus disease 2019 (COVID‐19) vaccine. 1 This represents an extraordinary scientific and logistic achievement — in 18 months, researchers, manufacturers and ...
Safety & effectiveness of COVID-19 vaccines: A narrative ...
The population uptake of two doses of Covid-19 vaccines in the United Kingdom (in persons >12 years of age) as of February 2022 was 84.5%, 5 and it has now been more than 6 months since the second ...
Effectiveness of COVID-19 vaccination against ...
Discussion. A two-dose regimen of BNT162b2 (30 μg per dose, given 21 days apart) was found to be safe and 95% effective against Covid-19. The vaccine met both primary efficacy end points, with ...
Objective To estimate the effectiveness of mRNA vaccines against moderate and severe covid-19 in adults by time since second, third, or fourth doses, and by age and immunocompromised status. Design Test negative case-control study. Setting Hospitals, emergency departments, and urgent care clinics in 10 US states, 17 January 2021 to 12 July 2022. Participants 893 461 adults (≥18 years ...
The effectiveness of the mRNA vaccines in preventing COVID-19 disease progression in 2021 set new expectations about the role of prevention interventions for the disease. Efficacy observed in the trials was more than 90%.1,2 The efficacy of other vaccines evaluated in large randomised trials, such as the Oxford-AstraZeneca (70%) and Sputnik V (91%) vaccines, have been criticised for elements ...
While efficacious vaccines have been developed to inoculate against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; also known as COVID-19), public vaccine hesitancy could still ...
COVID-19 vaccine development: milestones, lessons and ...
Objective To evaluate the impact of vaccine scale-up on population level covid-19 mortality and incidence in the United States. Design Observational study. Setting US county level case surveillance and vaccine administration data reported from 14 December 2020 to 18 December 2021. Participants Residents of 2558 counties from 48 US states. Main outcome measures The primary outcome was county ...
rogerashford / iStock. The US Food and Drug Administration (FDA) today announced that it has granted emergency use authorization for Novavax's updated COVID-19 vaccine.. Approval of the protein-based vaccine comes about a week after the FDA green-lighted the two updated mRNA vaccines—made by Moderna and Pfizer-BioNTech—which target the KP.2 variant. . The Novavax vaccine targets JN.1, the ...
As of June 19, 2021, Covid-19 vaccines are estimated to have prevented 7.2 million infections and 27,000 deaths in England alone. 12 Similarly, ... Brazil: a test-negative case-control study.
Introduction. The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in over 192 million cases and 4.1 million deaths as of July 22, 2021. 1 This pandemic has brought along a massive burden in morbidity and mortality in the healthcare systems. Despite the implementation of stringent public health measures, there ...
Pfizer and BioNTech Conclude Phase 3 Study of COVID ...
COVID-19 vaccines show excellent efficacy in clinical trials and effectiveness in real-world data, but some people still become infected with SARS-CoV-2 after vaccination. ... This prospective, community-based, nested, case-control study used self-reported data (eg, on demographics, geographical location, health risk factors, and COVID-19 test ...
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are pivotal in combating coronavirus disease 2019 (COVID-19); however, the declining antibody titers postvaccination pose challenges for sustained protection and herd immunity. Although gut microbiome is reported to affect the early antibody response after vaccination, its impact on the longevity of vaccine ...
Evaluating the COVID-19 vaccination program in Japan ...
We identified 93 partnerships with ≥2 entities and 190 single entities developing COVID-19 vaccines registered by the WHO. Of the 81 partnerships we deductively analyzed, we found that 71 had a company partner. Further, we found that 46 (56.8%) were involved in " materials transfer" and 35 (43.2%) in " knowledge sharing".
Strategy for COVID-19 vaccination in India: the country with ...
Students receiving the COVID 19 vaccine at Hawley Armory on April 8, 2021. The rollout of the vaccines across the state in the spring helped set up a return to a more familiar university experience.
Risk of autoimmune diseases following COVID-19 and ...
Association between COVID-19 Vaccination and SARS-CoV-2 Infection among Household Contacts of Infected Individuals: A Prospective Household Study in England, Vaccines, 12, 2, (113), (2024). https ...
Feedback from COVID-19 suggests that vaccination alone is inefficient to eradicate such a virus and a fine understanding of the parameters of its diffusion is a key factor ... The link between bike sharing and subway use during the Covid-19 pandemic: the case-study of New York's Citi Bike. Transp. Res. Interdiscip. Perspect. 6, 100166 (2020)
In addition, Cabinet has now also removed COVID-19 from the list of quarantinable infectious diseases. News article ; Notifiable diseases COVID-19 Public health New Zealand's first health strategy for people with rare disorders. Publication date: 25 July 2024. The Ministry of Health has published New Zealand's first dedicated, health system ...
These studies showed that pregnant women diagnosed with COVID-19 are more likely to experience pre-eclampsia, 8, 12, 13, 25 gestational hypertension 9 and preterm birth. 7, 8, 12-14, 26 Whilst a meta-analysis of 117,552 vaccinated pregnant women underscores COVID-19 vaccine efficacy in preventing infection and hospitalization, 27, 28 few ...