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Medical Research Archives (ISSN: 2375-1924)

Publisher European Society of Medicine

ISSN-L 2375-1924

ISSN 2375-1924

IF(Impact Factor) 2024 Evaluation Pending

Website http://esmed.org

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Last modified: 2023-05-05 22:47:29

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Medical research archives  

Papers published on a yearly basis, utilizing patient hope and outcome expectations to facilitate treatment gains.

47  citations

The Impact of the Role of Doctor of Nursing PracticeNurses on Healthcare and Leadership

22  citations

Personalizing Medicine in Head and Neck Squamous Cell Carcinoma: The Rationale for Combination Therapies.

16  citations

Answering Research Questions Using an Existing Data Set

14  citations

Probabilistic Modeling of Blood Vessels for Segmenting Magnetic Resonance Angiography Images

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Archives of Medical Research

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Elsevier Inc.

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01884409, 18735487

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The set of journals have been ranked according to their SJR and divided into four equal groups, four quartiles. Q1 (green) comprises the quarter of the journals with the highest values, Q2 (yellow) the second highest values, Q3 (orange) the third highest values and Q4 (red) the lowest values.

The SJR is a size-independent prestige indicator that ranks journals by their 'average prestige per article'. It is based on the idea that 'all citations are not created equal'. SJR is a measure of scientific influence of journals that accounts for both the number of citations received by a journal and the importance or prestige of the journals where such citations come from It measures the scientific influence of the average article in a journal, it expresses how central to the global scientific discussion an average article of the journal is.

Evolution of the number of published documents. All types of documents are considered, including citable and non citable documents.

This indicator counts the number of citations received by documents from a journal and divides them by the total number of documents published in that journal. The chart shows the evolution of the average number of times documents published in a journal in the past two, three and four years have been cited in the current year. The two years line is equivalent to journal impact factor ™ (Thomson Reuters) metric.

Evolution of the total number of citations and journal's self-citations received by a journal's published documents during the three previous years. Journal Self-citation is defined as the number of citation from a journal citing article to articles published by the same journal.

Evolution of the number of total citation per document and external citation per document (i.e. journal self-citations removed) received by a journal's published documents during the three previous years. External citations are calculated by subtracting the number of self-citations from the total number of citations received by the journal’s documents.

International Collaboration accounts for the articles that have been produced by researchers from several countries. The chart shows the ratio of a journal's documents signed by researchers from more than one country; that is including more than one country address.

Not every article in a journal is considered primary research and therefore "citable", this chart shows the ratio of a journal's articles including substantial research (research articles, conference papers and reviews) in three year windows vs. those documents other than research articles, reviews and conference papers.

Ratio of a journal's items, grouped in three years windows, that have been cited at least once vs. those not cited during the following year.

Evolution of the percentage of female authors.

Evolution of the number of documents cited by public policy documents according to Overton database.

Evoution of the number of documents related to Sustainable Development Goals defined by United Nations. Available from 2018 onwards.

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Linking ISSN (ISSN-L): 2375-1916

URL http://www.journals.ke-i.org/index.php/mra/issue/archive

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Title proper: Medical research archives.

Other variant title: MRA

Country: United States

Medium: Online

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Last modification date: 06/02/2021

Type of record: Confirmed

ISSN Center responsible of the record: ISSN National Centre for the USA For all potential issues concerning the description of the publication identified by this bibliographic record (missing or wrong data etc.), please contact the ISSN National Centre mentioned above by clicking on the link.

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Archives of Medical Research

Journal Abbreviation: ARCH MED RES Journal ISSN: 0188-4409

About Archives of Medical Research

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Medical research archives.

Journal ISSN 2375-1924 Online 2375-1916 Paper Peer Reviewed Yes Publication Freqency Monthly Priority Low Journal ID 172911 Created On Mon, 12/11/2023 - 12:00 Updated On Mon, 12/11/2023 - 12:00 Journal Publisher(s) European Society of Medicine

European Journal of Medical Research

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Vacancy: European Journal of Medical Research Editor-in-Chief

BMC is seeking to appoint an Editor-in-Chief to succeed Martijn van Griensven and Edwin Bölke, who will be stepping down as Editors of the journal in December 2024. 

Closing date for applications : 30 September 2024

Learn more about the role and how to apply  here !

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Article of the Month: Herpesviruses reactivation following COVID-19 vaccination: a systematic review and meta-analysis

The reactivation of herpesviruses (HHV) in COVID-19 patients is evident in the literature. Several reports have been published regarding the reactivation of these viruses (HSV, VZV, EBV, and CMV) among those who got COVID-19 vaccines. This study aimed to review the current evidence to assess whether HHVs reactivation has any association with the prior administration of COVID-19 vaccines.

Aims and scope

European Journal of Medical Research publishes translational, preclinical and clinical research of international interest across all medical disciplines, enabling clinicians and other researchers to learn about developments and innovations within these disciplines and across the boundaries between disciplines. The journal also has a special focus on internal medicine, surgery, neurology, infectious diseases and intensive care medicine.

European Journal of Medical Research publishes high quality research and reviews and aims to ensure that the results of all well-conducted research are published, regardless of their outcome. 

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About the Editors-in-Chief

Prof Bölke is a specialist in surgery, visceral surgery, emergency medicine, and has further training in surgical intensive care medicine and sports medicine. He works as a full time specialist in radiation oncology at the University of Düsseldorf. Since 2010, Prof Bölke has been a senior physician at the Clinic for Radiation Oncology at the University Hospital in Düsseldorf. He has been a professor for radiation oncology at the University of Düsseldorf since 2012. He is an author of more than 185 papers in PubMed.

Annual Journal Metrics

Citation Impact 2023 Journal Impact Factor: 2.8 5-year Journal Impact Factor: 2.9 Source Normalized Impact per Paper (SNIP): 0.818 SCImago Journal Rank (SJR): 0.736

Speed 2023 Submission to first editorial decision (median days): 36 Submission to acceptance (median days): 151

Usage 2023 Downloads: 1,790,363 Altmetric mentions: 5,415

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ISSN: 2047-783X

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Medical research archives (Q27726857)

• Med Res Arch

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Review article, evidence-based healthcare practice adoption: the impact of electronic health records, about the author(s).

Background:  For healthcare institutions, proper documentation of the upkeep of patient medical records is imperative. In addition, without a record of the patient’s medical history, the doctors are unable to demonstrate that the treatment was delivered correctly.

Aim:  The primary objective of this research was to determine the influence of electronic health records (EHR) towards the adoption of evidence-based healthcare practice (EBHP) in South African public healthcare.

Methods:  The study used a quantitative methodology, and a self-administered questionnaire was used to collect data from 300 healthcare professionals. In all, 450 questionnaires were distributed, and of those, 150 were unfit for data analysis because of insufficient data, leaving a total of 300 responses. Data were analysed using exploratory factor analysis (EFA) to identify latent constructs. Confirmatory factor analysis (CFA) was used to assess the validity and reliability of these constructs. The appropriateness of the measurement model was then assessed using fit indices for a structural equation model.

Results:  The findings show EHR had a direct influence on information quality, medical error reduction, diagnosis and treatment of diseases as well as better coordination of patient’s care. In addition, the results show that EHR-based clinical decision support is crucial for practising evidence-based healthcare and plays a significant role in the quality of healthcare, particularly in the management of diseases and preventative care. As all requirements for validity and reliability (root mean square error of approximation [RMSEA] = 0.085, comparative fit index [CFI] = 0.956 and χ 2 / df  = 2.513) have been satisfied, the model is considered valid and reliable.

Conclusion:  When healthcare professions such as doctors and nurses accurately record patients’ medical histories, they are able to make successful medical decisions and prescribe medications based on the patients’ past and present medical histories. Electronic health records systems facilitate the easier and more efficient exchange of patient data between medical schools, research labs, specialists, pharmacies and other healthcare institutions. Furthermore, they provide medical professionals with resources and up-to-date information to help them deliver EBHP that can benefit patients by reducing or even eliminating medical errors.

Contribution:  The study contributes theoretically to the field of information systems by outlining a model that includes the variables that affect the adoption of EBHPs in public hospitals.

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The Medical Research Archives is the official journal of the European Society of Medicine. It publishes original research, reviews, and case reports addressing health issues of interest to a global community of medical professionals. The journal was founded in 2014 and has just published its 119th issue.

Special Issue: Challenges and Opportunities in Health Disparities

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Online ISSN: 2375-1924 Print ISSN: 2375-1916 PubMed ID: 101668511

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Scientists Discover “Completely Different” New Risk Factor for Heart Disease

A new study has settled a prolonged dispute within the medical community by showing that mutations associated with clonal hematopoiesis heighten the risk of atherosclerosis in affected individuals.

In addition to the established risk factors for cardiovascular disease—such as high blood pressure, high cholesterol, diabetes, obesity, smoking, and lack of physical activity—another factor must now be considered: clonal hematopoiesis. This condition, caused by acquired mutations in blood stem cells, has already been linked to an increased risk of cardiovascular events.

However, until now it was uncertain if clonal hematopoiesis was a cause or consequence of cardiovascular disease . Now, a new study published in Nature Medicine and carried out by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) resolves this critical debate by establishing clonal hematopoiesis as a new risk factor for atherosclerosis—the formation of lesions in the arterial wall that underlies most cardiovascular disorders.

In a second study, published in the European Heart Journal , the CNIC scientists propose the ancient medication colchicine as the central plank of personalized strategies to alleviate the effects of clonal hematopoiesis associated with acquired mutations in the TET2 gene. The results of these important studies will be presented today at the European Society of Cardiology meeting in London, UK.

Acquired mutations in blood cell lineages: a new cause of atherosclerosis

An adult person produces hundreds of thousands of blood cells every day. This high rate of cell division unavoidably entails the accumulation of DNA mutations in the dividing cells. These mutations are known as somatic mutations, and are acquired, not inherited. “Although most somatic mutations are innocuous, some give the affected cells a competitive advantage that allows them to expand and progressively accumulate, generating clonal populations of mutated blood cells, a phenomenon known as clonal hematopoiesis,” explained José Javier Fuster, who led the Nature Medicine study, for which it has received support from Fundación “la Caixa” .

These mutations had already been proposed as a possible risk factor for cardiovascular disease; however, the exact nature of the relationship remained unclear. As Dr. José Javier Fuster, coordinator of the CNIC “Novel Mechanisms of Atherosclerosis” program, explained, “some earlier studies suggested that somatic mutations linked to clonal hematopoiesis contribute directly to cardiovascular disease and thereby accelerating the development of atherosclerosis. On the other hand, others proposed that it is atherosclerosis that causes clonal hematopoiesis by increasing the proliferation of blood stem cells and thereby generating a higher proportion of mutated blood cells.”

The Nature Medicine study clarifies the relationship between clonal hematopoiesis and atherosclerosis through a longitudinal analysis of data from the PESA-CNIC-Santander study. PESA (Progression of Early Subclinical Atherosclerosis) is a prospective study of more than 4000 apparently healthy middle-aged participants who have undergone periodic examinations using advanced imaging technology since 2010 to detect the presence and progression of asymptomatic atherosclerosis.

PESA is a collaborative initiative of the CNIC and Santander Bank. “The PESA study has already made very important contributions to our understanding of cardiovascular disease, and its longitudinal nature and unique characteristics provide an ideal framework for carrying out this important study on the relationship between clonal hematopoiesis and atherosclerosis,” said Dr. Valentín Fuster, CNIC General Director, principal investigator on the PESA study, and co-lead author on the Nature Medicine study.

The researchers used high-sensitivity DNA sequencing technology to detect somatic mutations in blood samples and assessed the presence and progression of atherosclerosis detected with noninvasive imaging techniques in the PESA participants. “The study was a multidisciplinary effort involving specialists in basic science and cardiology, together with the specialized technical expertise of the Bioinformatics, Genomics, and Clinical Trials Units at the CNIC,” said José Javier Fuster.

The results of the study clearly demonstrate that participants who had mutations linked to clonal hematopoiesis at the start of the study were more likely to develop atherosclerosis in the following years. On the other hand, the presence and extent of atherosclerosis had no influence on the expansion of mutated blood cells. “These results indicate that the mutations contribute to the development of atherosclerosis but are not a consequence of it,” explained co-first author Miriam Díez-Díez. “However, it remains possible that other factors, such as genetic profile or lifestyle, might modulate the effects of clonal hematopoiesis, and future studies are planned to examine this possibility,” added Beatriz L. Ramos-Neble, the other co-first author on the study.

The results of the study have clear clinical implications and identify clonal hematopoiesis as a cardiovascular risk factor completely different from the traditional risk factors studied in recent decades. This novelty holds promise for the development of new strategies for the prevention of cardiovascular disorders. “By demonstrating that the mutations linked to clonal hematopoiesis precede atherosclerosis and contribute to its development, our research suggests that blocking the effects of these somatic mutations could help to prevent cardiovascular disease,” claimed Dr. José Javier Fuster. The second CNIC study, published in the European Heart Journal , lays the groundwork for this.

An ancient drug to alleviate a new cardiovascular risk factor

The best-characterized mutations linked to clonal hematopoiesis are those that affect the TET2 gene. In a 2017 study published in Science , Dr. José Javier Fuster’s team showed that mutations in TET2 accelerate the development of atherosclerosis in animal models. In the new study published in the European Heart Journal , the CNIC group, in partnership with the team led by Dr. Pradeep Natarajan at the Broad Institute in Boston, shows that the adverse effects of TET2 mutations on cardiovascular health can be alleviated by treatment with the anti-inflammatory drug colchicine.

The CNIC team demonstrated that administration of colchicine to animals with TET2 mutations slows the development of atherosclerosis to a rate similar to that seen in non-mutated animals. In parallel, the Broad Institute scientists showed that individuals with TET2 mutations and who had been treated with colchicine for other conditions had a lower risk of myocardial infarction than untreated patients with similar mutations.

Plant preparations containing colchicine have been used for thousands of years in traditional medicine, and the drug is used in modern medicine to treat inflammatory conditions such as gout. “Colchicine is a very cheap medicine, available throughout the world, and is approved for the prevention of cardiovascular disease by the European Medicines Agency and by the FDA in the USA. There is, therefore, no major obstacle to its use for the prevention of cardiovascular disease in people with TET2 mutations,” emphasized Dr. María Ángeles Zuriaga, who conducted the experimental studies at the CNIC and is the first author on the European Heart Journal study.

Dr. José Javier Fuster underlined the important implications of the study for personalized medicine. “In clonal hematopoiesis, each mutated gene acts through different mechanisms and will therefore likely require specific interventions to target its effects. This study lays the groundwork for using colchicine for/in the personalized prevention of cardiovascular disease of carriers of mutations in TET2 , but new clinical trials will be needed to conclusively demonstrate its effectiveness in these individuals.”

References: “Unidirectional association of clonal hematopoiesis with atherosclerosis development” by Miriam Díez-Díez, Beatriz L. Ramos-Neble, Jorge de la Barrera, J. C. Silla-Castro, Ana Quintas, Enrique Vázquez, M. Ascensión Rey-Martín, Benedetta Izzi, Lucía Sánchez-García, Inés García-Lunar, Guiomar Mendieta, Virginia Mass, Nuria Gómez-López, Cristina Espadas, Gema González, Antonio J. Quesada, Ana García-Álvarez, Antonio Fernández-Ortiz, Enrique Lara-Pezzi, Ana Dopazo, Fátima Sánchez-Cabo, Borja Ibáñez, Vicente Andrés, Valentín Fuster and José J. Fuster, 30 August 2024, Nature Medicine . DOI: 10.1038/s41591-024-03213-1

“Colchicine prevents accelerated atherosclerosis in TET2-mutant clonal haematopoiesis” by María A Zuriaga, Zhi Yu, Nuria Matesanz, Buu Truong, Beatriz L Ramos-Neble, Mari C Asensio-López, Md Mesbah Uddin, Tetsushi Nakao, Abhishek Niroula, Virginia Zorita, Marta Amorós-Pérez, Rosa Moro, Benjamin L Ebert, Michael C Honigberg, Domingo Pascual-Figal, Pradeep Natarajan and José J Fuster, 30 August 2024, European Heart Journal . DOI: 10.1093/eurheartj/ehae546

The PESA study is cofunded by the CNIC and Santander Bank. The two studies were additionally funded by the Spanish Ministerio de Ciencia, Innovación e Universidades (PLEC2021-008194), the Spanish cardiovascular research network (CIBERCV), Fundación “la Caixa” (LCF/PR/HR17/52150007; LCF/PR/HR22/52420011), and Fundación ‘La Marató TV3’ (202314-31).

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“In addition to the established risk factors for cardiovascular disease—such as high blood pressure, high cholesterol, diabetes, obesity, smoking, and lack of physical activity—another factor must now be considered: clonal hematopoiesis.” What they call established risk factors I, now eighty years of age, call co-symptoms.

The group photo suggests instead of researching clonal hematopoiesis they probably should be researching allergy/gout related obesity, likely related to the theme of the article via high serum levels of uric acid and/or low levels of calcium (as per ionic, not blood serum, testing). As to the presence of mutated red blood cells, lacking the skills and resources to do genetic testing I can only suspect “…the formation of lesions in the arterial wall that underlies most cardiovascular disorders.” is caused by uric acid crystallizing in the smooth muscle tissue lining the affected arteries, caused by low core temperature due to metabolic syndrome.

Bottom line: more great research undermined by mainstream medicine’s failure to recognize and research Dr. Arthur F. Coca’s kind of allergies since the early 1930s. I’ve never tried colchicine for my own mostly asymptomatic gout but I’ve read it can have serious side effects.

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• National Institutes of Health

Whole Person Health: What It Is and Why It's Important

.header_greentext{color:greenimportant;font-size:24pximportant;font-weight:500important;}.header_bluetext{color:blueimportant;font-size:18pximportant;font-weight:500important;}.header_redtext{color:redimportant;font-size:28pximportant;font-weight:500important;}.header_darkred{color:#803d2fimportant;font-size:28pximportant;font-weight:500important;}.header_purpletext{color:purpleimportant;font-size:31pximportant;font-weight:500important;}.header_yellowtext{color:yellowimportant;font-size:20pximportant;font-weight:500important;}.header_blacktext{color:blackimportant;font-size:22pximportant;font-weight:500important;}.header_whitetext{color:whiteimportant;font-size:22pximportant;font-weight:500important;}.header_darkred{color:#803d2fimportant;}.green_header{color:greenimportant;font-size:24pximportant;font-weight:500important;}.blue_header{color:blueimportant;font-size:18pximportant;font-weight:500important;}.red_header{color:redimportant;font-size:28pximportant;font-weight:500important;}.purple_header{color:purpleimportant;font-size:31pximportant;font-weight:500important;}.yellow_header{color:yellowimportant;font-size:20pximportant;font-weight:500important;}.black_header{color:blackimportant;font-size:22pximportant;font-weight:500important;}.white_header{color:whiteimportant;font-size:22pximportant;font-weight:500important;} what is whole person health.

Whole person health involves looking at the whole person—not just separate organs or body systems—and considering multiple factors that promote either health or disease. It means helping and empowering individuals, families, communities, and populations to improve their health in multiple interconnected biological, behavioral, social, and environmental areas. Instead of just treating a specific disease, whole person health focuses on restoring health, promoting resilience, and preventing diseases across a lifespan.

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Health and disease are not separate, disconnected states but instead occur on a path that can move in two different directions, either toward health or toward disease.

On this path, many factors, including one’s biological makeup; some unhealthy behaviors, such as poor diet, sedentary lifestyle, chronic stress, and poor sleep; as well as social aspects of life—the conditions in which people are born, grow, live, work, and age—can lead to chronic diseases of more than one organ system. On the other hand, self-care, lifestyle, and behavioral interventions may help with the return to health.

Chronic diseases, such as diabetes, cardiovascular disease, obesity, and degenerative joint disease, can also occur with chronic pain, depression, and opioid misuse—all conditions exacerbated by chronic stress. Some chronic diseases increase the immediate and long-term risks with COVID-19 infection. Understanding the condition in which a person has lived, addressing behaviors at an early stage, and managing stress can not only prevent multiple diseases but also help restore health and stop the progression to disease across a person’s lifespan.

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Some health care systems and programs are now focusing more on whole person health.

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The VA’s Whole Health System of Care and Whole Health approach aims to improve the health and well-being of veterans and to address lifestyle and environmental root causes of chronic disease. The approach shifts from a disease-centered focus to a more personalized approach that engages and empowers veterans early in and throughout their lives to prioritize healthy lifestyle changes in areas like nutrition, activity, sleep, relationships, and surroundings. Conventional testing and treatment are combined with complementary and integrative health approaches that may include acupuncture, biofeedback, massage therapy, yoga, and meditation.

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The Total Force Fitness program arose within the U.S. Department of Defense Military Health System in response to the need for a more holistic approach—a focus on the whole person instead of separate parts or only symptoms—to the demands of multiple deployments and the strains on the U.S. Armed Forces and their family members. The focus extends the idea of total fitness to include the health, well-being, and resilience of the whole person, family, community, and U.S. military.

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Established in 2020, the Whole Health Institute’s Whole Health model helps people identify what matters most to them and build a plan for their journey to whole health. The model provides tools to help people take good care of their body, mind, and spirit, and involves working with a health care team as well as tapping into the support of family, friends, and communities.

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The North Carolina Department of Health and Human Services has incorporated a whole person health approach into its health care system by focusing on integrating physical, behavioral, and social health. The state has taken steps to encourage collaborative behavioral health care and help resolve widespread inequities in social conditions, such as housing and nutritious food access.

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The Ornish Program for Reversing Heart Disease is an intensive cardiac rehabilitation program that has been shown to reverse the progression of coronary heart disease through lifestyle changes, without drugs or surgery. The program is covered by Medicare and some health insurance companies. The program’s lifestyle changes include exercise, smoking cessation, stress management, social support, and a whole-foods, plant-based diet low in total fat. The program is offered by a team of health care professionals who provide the support that individuals need to make and maintain lasting changes in lifestyle.

.header_greentext{color:green!important;font-size:24px!important;font-weight:500!important;}.header_bluetext{color:blue!important;font-size:18px!important;font-weight:500!important;}.header_redtext{color:red!important;font-size:28px!important;font-weight:500!important;}.header_darkred{color:#803d2f!important;font-size:28px!important;font-weight:500!important;}.header_purpletext{color:purple!important;font-size:31px!important;font-weight:500!important;}.header_yellowtext{color:yellow!important;font-size:20px!important;font-weight:500!important;}.header_blacktext{color:black!important;font-size:22px!important;font-weight:500!important;}.header_whitetext{color:white!important;font-size:22px!important;font-weight:500!important;}.header_darkred{color:#803d2f!important;}.Green_Header{color:green!important;font-size:24px!important;font-weight:500!important;}.Blue_Header{color:blue!important;font-size:18px!important;font-weight:500!important;}.Red_Header{color:red!important;font-size:28px!important;font-weight:500!important;}.Purple_Header{color:purple!important;font-size:31px!important;font-weight:500!important;}.Yellow_Header{color:yellow!important;font-size:20px!important;font-weight:500!important;}.Black_Header{color:black!important;font-size:22px!important;font-weight:500!important;}.White_Header{color:white!important;font-size:22px!important;font-weight:500!important;} What does research show about whole person health?

A growing body of research suggests the benefits of healthy behaviors, environments, and policies to maintain health and prevent, treat, and reverse chronic diseases. This research includes several large, long-term epidemiological studies—such as the Framingham Heart Study, Nurses’ Health Study, and Adventist Health Studies—that have evaluated the connections between lifestyle, diet, genetics, health, and disease.

There is a lack, however, of randomized controlled trials and other types of research on multicomponent interventions and whole person health. Challenges come with conducting this type of research and with finding appropriate ways to assess the evidence. But opportunities are emerging to explore new paths toward reliable and rigorous research on whole person health.

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Yes, NCCIH plans to fund research on whole person health . (Details can be found in the NCCIH Strategic Plan FY 2021–2025: Mapping a Pathway to Research on Whole Person Health . )

By deepening the scientific understanding of the connections that exist across the different areas of human health, researchers can better understand how conditions interrelate, identify multicomponent interventions that address these problems, and determine the best ways to support individuals through the full continuum of their health experience, including the return to health.

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Nccih clearinghouse.

The NCCIH Clearinghouse provides information on NCCIH and complementary and integrative health approaches, including publications and searches of Federal databases of scientific and medical literature. The Clearinghouse does not provide medical advice, treatment recommendations, or referrals to practitioners.

Toll-free in the U.S.: 1-888-644-6226

Telecommunications relay service (TRS): 7-1-1

Website: https://www.nccih.nih.gov

Email: [email protected] (link sends email)

Know the Science

NCCIH and the National Institutes of Health (NIH) provide tools to help you understand the basics and terminology of scientific research so you can make well-informed decisions about your health. Know the Science features a variety of materials, including interactive modules, quizzes, and videos, as well as links to informative content from Federal resources designed to help consumers make sense of health information.

Explaining How Research Works (NIH)

Know the Science: How To Make Sense of a Scientific Journal Article

Understanding Clinical Studies (NIH)

A service of the National Library of Medicine, PubMed® contains publication information and (in most cases) brief summaries of articles from scientific and medical journals. For guidance from NCCIH on using PubMed, see How To Find Information About Complementary Health Approaches on PubMed .

Website: https://pubmed.ncbi.nlm.nih.gov/

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• Aggarwal M, Ornish D, Josephson R, et al. Closing gaps in lifestyle adherence for secondary prevention of coronary heart disease. American Journal of Cardiology. 2021;145:1-11.
• Centers for Medicare & Medicaid Services. Decision Memo for Intensive Cardiac Rehabilitation (ICR) Program—Dr. Ornish’s Program for Reversing Heart Disease (CAG-00419N). Accessed at https://www.cms.gov/ on April 26, 2021.
• Deuster PA, O’Connor FG. Human performance optimization: culture change and paradigm shift. Journal of Strength and Conditioning Research. 2015;29(suppl 11):S52-S56.
• Gaudet T, Kligler B. Whole health in the whole system of the Veterans Administration: how will we know we have reached this future state? Journal of Alternative and Complementary Medicine. 2019;25(S1):S7-S11.
• Malecki HL, Gollie JM, Scholten J. Physical activity, exercise, whole health, and integrative health coaching. Physical Medicine and Rehabilitation Clinics of North America. 2020;31(4):649-663.
• National Center for Complementary and Integrative Health. NCCIH Strategic Plan FY 2021–2025: Mapping a Pathway to Research on Whole Person Health. National Center for Complementary and Integrative Health website. Accessed at https://www.nccih.nih.gov/about/nccih-strategic-plan-2021-2025 on May 14, 2021.
• North Carolina Department of Health and Human Services website. Healthy Opportunities and Medicaid Transformation. Accessed at https://www.ncdhhs.gov/about/department-initiatives/healthy-opportunities/healthy-opportunities-pilots/healthy on April 26, 2021.
• Military Health System website. Total Force Fitness. Accessed at https://health.mil/Military-Health-Topics/Total-Force-Fitness on April 26, 2021.
• Tilson EC, Muse A, Colville K, et al. Investing in whole person health: working toward an integration of physical, behavioral, and social health. North Carolina Medical Journal. 2020;81(3):177-180.
• U.S. Department of Veterans Affairs website. Whole Health. Accessed at https://www.va.gov/wholehealth/ on April 26, 2021.
• U.S. Department of Veterans Affairs website. Whole Health Library. Accessed at  https://www.va.gov/wholehealthlibrary/ on April 26, 2021.
• Vodovotz Y, Barnard N, Hu FB, et al. Prioritized research for the prevention, treatment, and reversal of chronic disease: recommendations from the Lifestyle Medicine Research Summit. Frontiers in Medicine (Lausanne). 2020;7:585744.
• Whitehead AM, Kligler B. Innovations in care: complementary and integrative health in the Veterans Health Administration Whole Health System. Medical Care. 2020;58(9S)(suppl 2):S78-S79.

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• Alborzkouh P, Nabati M, Zainali M, et al. A review of the effectiveness of stress management skills training on academic vitality and psychological well-being of college students. Journal of Medicine and Life. 2015;8(4):39-44.
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Acknowledgments

NCCIH thanks Mary Beth Kester, M.S., and Helene M. Langevin, M.D., NCCIH, for their review of this publication.

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NCCIH has provided this material for your information. It is not intended to substitute for the medical expertise and advice of your health care provider(s). We encourage you to discuss any decisions about treatment or care with your health care provider. The mention of any product, service, or therapy is not an endorsement by NCCIH.

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