thesis topic in pulmonary medicine

• Medicine >
• Education & Training >
• Fellowship Programs >
• Pulmonary Disease and Critical Care >
• Research and Scholarship >

Potential Research Project Topics

Explore the broad range of research subjects you can undertake with the guidance of dedicated, enthusiastic faculty.

Topics for research projects with specific investigators include:

• Assessment of respiratory muscle function ( M. Jeffery Mador )
• Bacterial infection in COPD ( Sanjay Sethi )
• Biomedical Informatics ( Manoj Mammen )
• Characterization of alveolar macrophages ( Karin Provost )
• Clinical implications of sleep apnea ( M. Jeffery Mador )
• COVID-19 Management ( Francois Fadell )
• COVID19 ( Manoj Mammen )
• Critical Care Outcomes ( Francois Fadell )
• Data Science ( Rubelisa Oliveira ; Manoj Mammen )
• Epidemiology and clinical implications of antimicrobial resistance ( Sanjay Sethi )
• Health care associated pneumonia ( Ali El Solh )
• Host immunity in COPD ( Karin Provost )
• Identification and Prevention of Burnout ( Archana Mishra )
• Innate lung defense in COPD ( Sanjay Sethi )
• Insomnia ( Philippe Jaoude )
• Lung Cancer Screening ( Francois Fadell )
• Lung Nodules ( Francois Fadell )
• Medical Education ( Brian Ludwig ; David Holmes ; Linda Kahn ; Marlon Koenigsberg ; Andrea Manyon ; Andrew Symons ; David Thomas ; Diana Wilkins ; Gregory Cherr ; Michael Aronica ; Kim Strong Griswold ; Francois Fadell )
• Microbiome ( Manoj Mammen )
• Morbid obesity in the intensive care unit ( Ali El Solh )
• New therapeutics in COPD ( M. Jeffery Mador ; Sanjay Sethi )
• New therapeutics in cystic fibrosis ( Carla Frederick )
• Outcomes of pulmonary rehabilitation ( M. Jeffery Mador )
• Overlap Syndrome ( Philippe Jaoude )
• Pneumonia ( Philippe Jaoude )
• PTSD and sleep disorders ( Philippe Jaoude )
• Pulmonary Rehabilitation ( Francois Fadell )
• Quality Improvement ( Francois Fadell )
• Sepsis ( Francois Fadell )
• Sleep disordered breathing in cardiovascular disease ( Philippe Jaoude ; Ali El Solh )
• Smoking Cessation ( Francois Fadell )

Our Program at a Glance

Faculty-to-fellow ratio of 1-to-1.

Positions: 10 total, 3 to 4 new fellows accepted per year

Patient-to-fellow ratio of 10-to-1

Clinical experience: 22 months

ICU experience: 10 months

Continuity care clinical experience: 36 months

Choosing the Right Fellowship

Discover the components of a rewarding pulmonary disease and critical care fellowship. Find out how to select a program that fosters your development as a pulmonologist and critical care intensivist.

About Buffalo

• Search by keyword
• Search by citation

Page 1 of 78

Effects of sitting, supine, and prone postures on nasal patency in individuals with obstructive sleep apnea syndrome

Studies have found that in healthy individuals without nasal disease, changes in posture cause an increase in nasal resistance, especially in the prone posture. Many patients with obstructive sleep apnea syndr...

• View Full Text

Cepharanthine attenuates pulmonary fibrosis via modulating macrophage M2 polarization

Idiopathic pulmonary fibrosis (IPF) is a group of chronic interstitial pulmonary diseases characterized by myofibroblast proliferation and extracellular matrix (ECM) deposition. However, current treatments are...

IL-10 deficiency aggravates cell senescence and accelerates BLM-induced pulmonary fibrosis in aged mice via PTEN/AKT/ERK pathway

Pulmonary fibrosis (PF) is an aging-related progressive lung disorder. The aged lung undergoes functional and structural changes termed immunosenescence and inflammaging, which facilitate the occurrence of fib...

Effectiveness of Amikacin liposome inhalation suspension for refractory Mycobacterium avium complex pulmonary disease at 6 months post initiation

Amikacin  liposome inhalation suspension (ALIS) improved sputum culture conversion rate at 6 months for patients with refractory Mycobacterium avium complex pulmonary disease (MAC-PD) in an international phase 3 ...

The relationship between lung CT features and serum cryptococcal antigen titers in localized pulmonary cryptococcosis patients

To explore the associations of computed tomography (CT) image features with the serum cryptococcal antigen (CrAg) titers measured by the lateral flow assay (LFA) in localized pulmonary cryptococcosis patients.

Clinical features and outcomes of persons with cystic fibrosis and nocardia isolation: a systematic review

Recurrent respiratory infections are a leading cause of morbidity and mortality in persons with Cystic Fibrosis (pwCF). Recently, the emergence of Nocardia species as a potential pathogen in CF has raised ques...

Value of ultrathin bronchoscope in improving the endobronchial ultrasound localization rate and diagnosing peripheral pulmonary nodules by cryobiopsy

A 3.0-mm ultrathin bronchoscope (UTB) with a 1.7-mm working channel provides better accessibility to peripheral bronchi. A 4.0-mm thin bronchoscope with a larger 2.0-mm working channel facilitates the use of a...

Delayed sustained lung inflation for preterm neonates in neonatal intensive care unit: a randomized controlled trial

Sustained lung inflation (SLI) right after birth to decrease the use of mechanical ventilation of preterm infants is controversial because of potential harm. This randomized controlled trial was conducted to e...

Quantitative CT analysis of idiopathic pulmonary fibrosis and correlation with lung function study

Idiopathic Pulmonary Fibrosis (IPF) is a progressive fibrotic lung disease. However, the field of quantitative CT scan analysis in conjunction with pulmonary function test for IPF patients remains relatively u...

Successful treatment of mixed pulmonary Aspergillus and Mucor infection using intrabronchial amphotericin B infusion: a case report and literature review

Reports of pulmonary aspergillosis and mucormycosis co-infections are rare; thus, limited guidance is available on early diagnosis and treatment. We present a case of mixed pulmonary Aspergillus and Mucor infecti...

The association between testosterone, estradiol, estrogen sulfotransferase and idiopathic pulmonary fibrosis: a bidirectional mendelian randomization study

The causal relationships between testosterone, estradiol, estrogen sulfotransferase, and idiopathic pulmonary fibrosis (IPF) are not well understood. This study employs a bidirectional two-sample Mendelian Ran...

The effect of nebulized N-acetylcysteine on the phlegm of chronic obstructive pulmonary disease: the NEWEST study

Phlegm is prevalent symptom in patients with chronic obstructive pulmonary disease (COPD). Few studies have investigated the effectiveness of N-acetylcysteine (NAC) nebulizer therapy in COPD patients. We evalu...

Self-report underestimates the frequency of the acute respiratory exacerbations of COPD but is associated with BAL neutrophilia and lymphocytosis: an observational study

Research studies typically quantify acute respiratory exacerbation episodes (AECOPD) among people with chronic obstructive pulmonary disease (COPD) based on self-report elicited by survey questionnaire. Howeve...

Nontuberculous mycobacterial pulmonary disease presenting as bronchiolitis pattern on CT without cavity or bronchiectasis

This study aimed to investigate the radiological changes in patients with nontuberculous mycobacterial pulmonary disease (NTM-PD) having bronchiolitis patterns on computed tomography (CT).

Protection of Parkin over-expression on lung in rats with exertional heat stroke by activating mitophagy

To investigate the role of Parkin overexpression-induecd mitophagy in alleviating acute lung injury of exertional heat stroke(EHS) rats.

Impact of the coronavirus disease 2019 pandemic on hospital admissions for idiopathic pulmonary fibrosis: a nationwide population-based study

Previous studies have consistently reported a decrease in hospital admissions for respiratory diseases during the coronavirus disease 2019 (COVID-19) pandemic. However, the impact of the pandemic on idiopathic...

The PROgnostic ModEl for chronic lung disease (PRO-MEL): development and temporal validation

Patients with chronic lung diseases (CLDs), defined as progressive and life-limiting respiratory conditions, experience a heavy symptom burden as the conditions become more advanced, but palliative referral ra...

Bronchial artery embolization versus conservative treatment for hemoptysis: a systematic review and meta-analysis

Bronchial artery embolization (BAE) is currently an important treatment for hemoptysis. However, there is no consensus in the efficacy and safety of BAE compared to conservative treatment for hemoptysis, which...

Determinants of cough-related quality of life in interstitial lung diseases

Interstitial lung diseases (ILD) include a wide range of diseases impacting lung parenchyma and leading to fibrosis and architectural distortion. Chronic cough and dyspnea are common symptoms which affect the ...

A case report of high-grade intraepithelial neoplasia of the bronchial mucosa

Lung cancer is the most common cause of cancer death worldwide and poses an immediate health threat. Despite decades of basic and clinical research, the 5-year survival rate for lung cancer patients is less th...

Phase 0 trials/ Intra-Target-Microdosing (ITM) and the lung: a review

The COVID-19 pandemic has highlighted the importance of efficient drug discovery in respiratory disease. The traditional set up of clinical trials is expensive and allows for significant attrition of new drugs...

The level of partial pressure of carbon dioxide affects organ perfusion in respiratory failure patients undergoing pressure support ventilation with venovenous extracorporeal membrane oxygenation: a prospective study

We evaluated the influence of different partial carbon dioxide pressure (PaCO 2 ) levels on organ perfusion in patients with respiratory failure receiving pressure-support ventilation with veno-venous extracorporea...

Characteristics of molecular subtypes and cinical outcomes in the immunotherapy Queue of extensive-stage small cell lung cancer patients

With a series of clinical trials confirming the sensitivity of small cell lung cancer (SCLC) to immunotherapy, research on personalized treatment for SCLC has gained increasing attention. Currently, the most w...

Clinical utility of metagenomic next-generation sequencing on bronchoalveolar lavage fluid in diagnosis of lower respiratory tract infections

In this study, we aimed to evaluate the clinical utility of Metagenomic Next-Generation sequencing (mNGS) on bronchoalveolar lavage fluid (BALF) in diagnosis of Lower Respiratory Tract Infections (LRTIs).

Utility of exhaled nitric oxide to guide mild asthma treatment in atopic patients and its correlation with asthma control test score: a randomized controlled trial

Fractional exhaled nitric oxide (FeNO) is used for the diagnosis and monitoring of asthma, although its utility to guide treatment and its correlation with other tools is still under discussion. We study the p...

Prediction models for postoperative pulmonary complications in intensive care unit patients after noncardiac thoracic surgery

Postoperative pulmonary complication (PPC) is a leading cause of mortality and poor outcomes in postoperative patients. No studies have enrolled intensive care unit (ICU) patients after noncardiac thoracic sur...

Associations between nocturnal bedtime and asthma among adults in the United States

Sleep disorders have a significant impact on asthma. The aim of this study was to explore the association between nocturnal bedtime and asthma among adults in the United States.

Effect of Tiotropium on eye findings in the treatment of chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a persistent, chronic inflammatory disease of the lungs. Tiotropium, used in the treatment of COPD, is a muscarinic receptor antagonist that provides long-acting...

Clinical and radiological features associated with rupture of pulmonary artery pseudoaneurysm: a retrospective study

Hemoptysis resulting from rupture of the pulmonary artery pseudoaneurysm (PAP) is massive and fatal, while factor contributing to the rupture of pseudoaneurysm remains elusive. This study aimed to elucidate th...

Lung adenocarcinoma concurrent with pulmonary cryptococcosis: a case report and literature review

Pulmonary cryptococcosis (PC) is a common opportunistic fungal infection caused by Cryptococcus neoformans or Cryptococcus gattii . PC primarily invades the respiratory system, followed by the central nervous syst...

Mortality from pulmonary hypertension in Europe 2001-2019

The incidence of Pulmonary Hypertension (PH) and Pulmonary Arterial Hypertension (PAH) is believed to be on the rise and is associated with poor outcomes.

Predictors of high-flow nasal cannula failure in COVID-19 patients in a northern Peruvian hospital

To determine predictors of high-flow nasal cannula (HFNC) failure in COVID-19 patients in a hospital in northern Peru.

Predictive role of red blood cell distribution width and hemoglobin-to-red blood cell distribution width ratio for mortality in patients with COPD: evidence from NHANES 1999–2018

Higher red blood cell distribution width (RDW) levels are associated with mortality in patients with chronic obstructive pulmonary disease (COPD). However, more convincing evidence is still lacking, and the re...

The association between ibuprofen administration in children and the risk of developing or exacerbating asthma: a systematic review and meta-analysis

Ibuprofen is one of the most commonly used analgesic and antipyretic drugs in children. However, its potential causal role in childhood asthma pathogenesis remains uncertain. In this systematic review, we asse...

Association of monoaminergic gene polymorphisms in chronic inflammatory pulmonary disease patients with successful smoking cessation

Albeit smoking cessation has unequivocal health benefits, attempts to quit are not unanimous, even in patient populations at high risk for smoking-related diseases cessation. Allelic variations of enzymes invo...

Clinical outcome of lung transplantation for chronic thromboembolic pulmonary hypertension

Chronic thromboembolic pulmonary hypertension (CTEPH) is a type of pulmonary hypertension with a low incidence. Despite pulmonary endarterectomy(PEA) being the preferred treatment for CTEPH, for patients who f...

Causal associations of obstructive sleep apnea with Chronic Respiratory Diseases: a Mendelian Randomization study

This study aimed to elucidate the causal relationship between Obstructive Sleep Apnea (OSA) and Chronic Respiratory Diseases (CRDs), employing Mendelian Randomization (MR) to overcome limitations inherent in o...

Pulmonary rehabilitation with balance training for fall reduction in chronic obstructive pulmonary disease: a randomized controlled trial

Available evidence suggests that adults with chronic obstructive pulmonary disease (COPD) performed substantially worse than healthy controls on many balance measures and balance training can improve the balan...

Baseline genetic abnormalities and effectiveness of osimertinib treatment in patients with chemotherapy-naïve EGFR-mutated NSCLC based on performance status

For patients treated with osimertinib as first-line therapy, there have been no studies comparing both progression-free survival (PFS) and overall survival (OS) according to performance status (PS). Furthermor...

Exploring mean platelet volume and neutrophil-to-albumin ratio as surrogate markers for monitoring tuberculosis treatment: a prospective longitudinal study

Tuberculosis (TB) remains a global health challenge, with India bearing a significant burden. Despite advancements in TB diagnosis and treatment, monitoring TB treatment is challenging, particularly in resourc...

Assessing the impact of triiodothyronine treatment on the lung microbiome of mice with pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF), an interstitial lung disease, is characterized by the exacerbation of progressive pulmonary fibrosis (PF). IPF primarily affects older individuals and can lead to respirato...

Prognostic performance of Krebs von den Lungen-6, surfactant protein A, surfactant protein D levels in the serum and bronchoalveolar lavage fluid in chronic fibrosing interstitial pneumonia: a retrospective study

The serum markers Krebs von den Lungen-6 (KL-6), surfactant protein A (SP-A), and surfactant protein D (SP-D) have been used for the diagnosis, differential diagnosis, and prognosis prediction of interstitial ...

Evaluation of progressive pulmonary fibrosis in non-idiopathic pulmonary fibrosis-interstitial lung diseases: a cross-sectional study

Progressive pulmonary fibrosis is the symptomatic, physiological, and radiological progression of interstitial lung diseases. The aim of this study was to examine the relationship between progressive pulmonary...

Prognostic analysis of destroyed-lung patients with preoperative massive hemoptysis: a 20-year retrospective study

Surgery is the main treatment option for destroyed-lung (DL) patients with life-threatening massive hemoptysis. However, short-term and long-term surgical safety and efficacy are unclear, prompting this study.

Improved diagnostic yield of peripheral pulmonary malignant lesions with emphysema using a combination of radial endobronchial ultrasonography and rapid on-site evaluation

This is a retrospective cohort study from a single center of Chest Medical District of Nanjing Brain Hospital Affiliated to Nanjing Medical University, Jiangsu Province, China. It was aim to evaluate the diagn...

Value of bronchoalveolar lavage fluid metagenomic next-generation sequencing in acute exacerbation of fibrosing interstitial lung disease: an individualized treatment protocol based on microbiological evidence

Acute exacerbation of fibrosing interstitial lung diseases (AE-ILD) is a serious life-threatening event per year. Methylprednisolone and/or immunosuppressive agents (ISA) are a mainstay in any regimen, under t...

Elevated inflammatory burden index increases mortality in adults with chronic inflammatory airway diseases: a nationwide cohort study

The objective of this study was to investigate the potential association between the inflammatory burden index (IBI) and the prevalence of chronic inflammatory airway diseases (CIAD), as well as mortality rate...

Effect of antigen removal in hypersensitivity pneumonitis

Antigen removal is a cornerstone of treatment of hypersensitivity pneumonitis (HP), but its association with transplant-free survival remains unclear. Further, HP guidelines conflict as to whether antigen remo...

Pediatric plastic bronchitis associated with smoke inhalation and influenza A: case report and literature review

Plastic bronchitis is a relatively uncommon illness that has been reported in all age groups. This case report describes a specific manifestation of plastic bronchitis in two pediatric brothers influenced by b...

Treatment patterns in patients with newly diagnosed COPD in the USA

Prompt and effective management with maintenance therapy (single or dual bronchodilator therapy) is recommended after the initial diagnosis of chronic obstructive pulmonary disease (COPD) to maintain lung func...

Important information

Editorial board  

For authors

For editorial board members

For reviewers

• Manuscript editing services

Annual Journal Metrics

Citation Impact 2023 Journal Impact Factor: 2.6 5-year Journal Impact Factor: 3.0 Source Normalized Impact per Paper (SNIP): 0.889 SCImago Journal Rank (SJR): 0.773 Speed 2023 Submission to first editorial decision (median days): 24 Submission to acceptance (median days): 138 Usage 2023 Downloads: 2,422,461 Altmetric mentions: 1,250

• More about our metrics

Peer-review Terminology

The following summary describes the peer review process for this journal:

Identity transparency: Single anonymized

Reviewer interacts with: Editor

Review information published: Review reports. Reviewer Identities reviewer opt in. Author/reviewer communication

More information is available here

• Follow us on Twitter

BMC Pulmonary Medicine

ISSN: 1471-2466

• Submission enquiries: [email protected]
• General enquiries: [email protected]

Dissertation Library

Our last decade has included the following phd dissertations, some of the exciting academic accomplishments from students and mentors of the pulmonary center:.

Claire Burgess Generation of Human Alveolar Epithelial Type I Cells From Pluripotent Stem Cells Mentor: Darrell Kotton Molecular & Translational Medicine

Mike Breen Extravascular B Cell Populations in the Influenza A Virus Experienced Lung Mentors: Rachel Fearns and Joseph P. Mizgerd Microbiology PhD

Elim Na The cytoprotective effects of leukemia inhibitory factor during bacterial pneumonia Mentor: Lee J. Quinton Molecular and Translational Medicine PhD

Christine Odom Liver-dependent lung remodeling during systemic inflammation alters responses to secondary infection Mentor: Lee J. Quinton Microbiology PhD

Carolina Lyon De Ana Novel subsets of resident lymphocytes in murine lungs recovered from pneumococcal pneumonia Mentor: Joseph P. Mizgerd Microbiology PhD

Emad Arafa Recovery from pneumococcal pneumonia remodels the pool of alveolar macrophages Mentor: Joseph P. Mizgerd Molecular and Translational Medicine PhD

Kim Barker The establishment and function of lung resident memory B cells after bacterial respiratory infection Mentor: Joseph P. Mizgerd Microbiology PhD

Elizabeth Becker Derivation of airway epithelium transcriptomic signatures of COPD phenotypes Mentor: Katrina Steiling Bioinformatics GRS PhD

Julia Hicks-Berthet Roles for YAP and TAZ in Lung Epithelial Biology Mentor: Bob Varelas Biochemistry PhD

Xu Ke Airway Gene Expression Alterations in Association with Radiographic Abnormalities of the Lung Mentor: Marc Lenburg Bioinformatics MD/PhD

Nathan Kingston Roles for Hippo effectors TAZ and YAP in cancer and fibrosis Mentor: Bob Varelas Biomedical Sciences (PiBS) PhD

Xingyi Shi Bronchial Gene Expression Associated with Airway Premalignancy and Lung Cancer Subtypes Mentor: Marc Lenburg Bioinformatics PhD

Yuliang (Leon) Sun The role of ATP binding cassette A3 (ABCA3) in health and disease using pluripotent stem cell-derived type II alveolar epithelial cells Mentor: Darrell Kotton Molecular and Translational Medicine PhD

Jiarui Zhang Genomic biomarker development to impact clinical management of patients at risk for lung cancer Mentor: Marc Lenburg Molecular and Translational Medicine PhD

Anant Balijepalli Design, synthesis, characterization, and evaluation of a cationic poly-amido-saccharide towards biocompatible nucleic acid delivery Mentor: Mark Grinstaff Biomedical Engineering PhD

Sean Corbett Approaches for identifying lung cell type responses to perturbation Mentor: Marc Lenburg Bioinformatics PhD

Yuri Kim Liver-dependent protection during pneumonia and sepsis Mentor: Lee J. Quinton Molecular and Translational Medicine PhD

George Kwong Induced pluripotent stem cell reporter systems for smooth muscle cell sheet engineering Mentor: Darrell Kotton Biomedical Engineering PhD

Timothy Norman Origin and maturation of the pulmonary lymphatic endothelium Mentor: Alan Fine Pathology PhD

Alicia Wooten Pneumococcal phosphodiesterase 2 mutation elicits a unique type I interferon response in macrophages Mentor: Joseph P. Mizgerd Molecular and Translational Medicine PhD

Julia Barrios Neural regulation of the pulmonary neuroendocrine system induce mucus overproduction Mentor: Xingbin Ai Molecular and Translational Medicine PhD

Grant Duclos Characterization of smoking-associated transcriptomic alterations to the human bronchial epithelium Mentor: Avrum Spira Molecular and Translational Medicine PhD

Terry Hsieh Mild traumatic brain injury augments innate immune responses through neurokinin and cholinergic signaling Mentor: Daniel Remick Pathology Md/PhD

Anjali Jacob Generation of mature type II alveolar epithelial cells from human pluripotent stem cells Mentor: Darrell Kotton Molecular and Translational Medicine PhD

Jacob Josef Kantrowitz Transcriptomic alterations underlying pathogenesis and carcinogenesis in COPD Mentor: Marc Lenburg Molecular and Translational Medicine MD/PhD

Ana Brandusa Pavel Multi-omics data integration for the detection and characterization of smoking related lung diseases Mentor: Marc Lenburg Bioinformatics PhD

Katherine Benson McCauley Pluripotent stem cell modeling of airway epithelial fate Mentor: Darrell Kotton Molecular Biology PhD

Joseph Perez-Rogers Development of a minimally invasive molecular biomarker for early detection of lung cancer Mentor: Marc Lenburg/Avrum Spira Bioinformatics PhD

Aleksander Szymaniak Polarity and Hippo signaling in epithelial cell fate regulation Mentor: Bob Varelas Biochemistry PhD

Fadie Coleman: Influence of macrophage NF-kappaB activation on pneumococcal pneumonia Mentor: Joseph P. Mizgerd Microbiology PhD

Elyse Kozlowski: Functional roles for the terminal uridyltransferase enzymes Zcchc6 and Zcchc11 in mammalian biology Mentor: Matthew R. Jones Molecular and Translational Medicine PhD

Nicole Stauffer Smith: Respiratory infections with pneumococci establish multi-pronged heterotypic protection against pneumonia Mentor: Joseph P. Mizgerd Pathology and Laboratory Medicine PhD

Greg Wasserman: A discrete population of ciliated cells express the piRNA binding protein MIWI2 to regulate lung inflammation Mentor: Matthew R. Jones Microbiology PhD

Kristie Hilliard The functional significance of the lung-liver axis during pneumonia Mentor: Lee J. Quinton Microbiology PhD

Rebecca Kusko Integrative transcriptomics in smoking related lung diseases Mentor: Avrum Spira Genetics & Genomics PhD

Teresa Wang Transcriptomics of the human airway epithelium reflect the physiologic response to inhaled environmental pollutants Mentor: Marc Lenburg Bioinformatics PhD

Joseph Gerrein Using gene and microRNA expression in the human airway for lung cancer diagnosis Mentor: Avrum Spira Bioinformatics PhD

Kahkeshan Hijazi The airway transcriptome as a measure of injury response to and recovery from smoking and alternative tobacco products Mentor: Marc Lenburg Bioinformatics PhD

John Mahoney The role of Yap in lung development Mentor: Wellington Cardoso Pathology & Laboratory Medicine PhD

Linh Aven Innervation defects as a mechanism of childhood asthma Mentor: Xingbin Ai Molecular Medicine, Cell and Molecular Biology PhD

John Brothers Characterizing and reassembling the COPD and ILD transcriptome using RNA-Seq Mentor: Marc Lenburg Bioinformatics PhD

Radhika Dixit The contribution of mesothelial cells to lung development Mentor: Alan Fine Molecular Medicine PhD

Joshua Campbell Genome-wide characterization of microRNA and gene expression patterns in smoking-related lung disease Mentor: Marc Lenburg Bioinformatics PhD

Julie Gil Zeskind Gene expression alterations associated with progression of emphysema and small airway disease in smokers with COPD Mentor: Avrum Spira/Marc Lenburg Bioinformatics PhD

Adam Gower Discovering biological connections between experimental conditions based on common patterns of differential gene expression Mentor: Avrum Spira/Marc Lenburg Bioinformatics PhD

Case Reports in Pulmonary Medicine

Loading... Editorial 01 November 2023 Editorial: Case reports in pulmonary medicine Rodrigo Torres-Castro  and  Suzanna Tanni 889 views 0 citations

Case Report 25 May 2023 Empyema caused by Fusobacterium nucleatum with squamous cell carcinoma of the lung: a case report and literature review Yue Sun ,  5 more  and  Lingling Wang 1,394 views 3 citations

Case Report 24 May 2023 Microscopic polyangiitis initially presenting with idiopathic pulmonary fibrosis: a case report Chi Shao ,  4 more  and  Kai Xu 1,522 views 0 citations

Case Report 20 March 2023 Successful management of tracheal lobular capillary hemangioma with arterial embolization followed by electrosurgical snaring via flexible bronchoscopy in an 11-year-old boy: A case report and literature review Xiaofen Tao ,  7 more  and  Yingshuo Wang 1,513 views 1 citations

Case Report 02 March 2023 Case report: Post-thoracoscopy pendelluft monitoring Zhibin Xiao ,  4 more  and  Xude Sun 1,193 views 0 citations

Case Report 14 February 2023 Pulmonary sarcoid-like granulomatosis induced by aluminum dust: A case report and literature review Xuqin Du ,  2 more  and  Qiao Ye 1,833 views 1 citations

Loading... Case Report 10 January 2023 Case report: Streptococcus pneumoniae pneumonia characterized by diffuse centrilobular nodules in both lungs Fangqi Zhang ,  3 more  and  Long Li 4,346 views 0 citations

Case Report 16 December 2022 Case report: Biliobronchial fistula after biliary tract stenosis Luís Maurício Batalin Júnior ,  6 more  and  Suzana Erico Tanni 1,578 views 2 citations

Case Report 15 December 2022 Case report: Rare epithelioid hemangioendothelioma occurs in both main bronchus and lung Jiuyu Gong ,  9 more  and  Pengtao Bao 1,588 views 2 citations

Loading... Review 24 November 2022 Tigecycline in the treatment of severe pneumonia caused by Chlamydia psittaci: A case report and literature review Jiaming Liu  and  Yuan Gao 2,344 views 3 citations

Case Report 25 October 2022 Case Report: Tracheal stenosis due to fibrotic bridges in a post-tracheostomy COVID-19 patient Lina Zuccatosta ,  5 more  and  Alessandro Di Marco Berardino 1,523 views 1 citations

Case Report 05 October 2022 Case Report: Use of endobronchial Watanabe spigot and coagulation factor XIII supplementation in the treatment of persistent pneumothorax due to pneumocystis pneumonia with human immunodeficiency virus infection Katsumasa Koyama ,  4 more  and  Koichi Tomoda 1,244 views 0 citations

Case Report 24 August 2022 Successful treatment of acute respiratory distress syndrome caused by hypervirulent Klebsiella pneumoniae with extracorporeal membrane oxygenation and continuous renal replacement therapy: A case report and literature review Wenzhong Peng ,  4 more  and  Pinhua Pan 1,423 views 2 citations

Loading... Case Report 22 July 2022 Anomalous systemic arterial supply to the left lower lung lobe: A case report Zhuo Wu ,  2 more  and  Xueying Yang 2,269 views 3 citations

Case Report 13 June 2022 Case Report: Rare Dynein Axonemal Heavy Chain 9 Mutations in a Han-Chinese Patient With Kartagener Syndrome Jingjing Feng ,  4 more  and  Zhijun Jie 1,516 views 2 citations

Loading... Case Report 10 June 2022 Pulmonary Actinomyces graevenitzii Infection: Case Report and Review of the Literature Yuan Yuan ,  4 more  and  Shuai Zhang 2,854 views 6 citations

Case Report 31 May 2022 Case Report: Massive Hemoptysis From a Spontaneously Regression Inflammatory Bronchial Polyp Yuichiro Iwamoto ,  4 more  and  Koichi Tomoda 1,236 views 1 citations

Chronic obstructive pulmonary disease and cardiac comorbidities: A cross-sectional study

Mohit kaushal.

Department of Respiratory Medicine, Smt. B. K. Shah Medical Institute and Research Centre, Vadodara, Gujarat, India

Parth S Shah

Arti d shah, stani a francis, nihar v patel, kavit k kothari, introduction:.

Chronic obstructive pulmonary disease (COPD) is a global health issue with cigarette smoking being an important risk factor. COPD affects pulmonary blood vessels, right ventricle, as well as left ventricle leading to the development of pulmonary hypertension (PH), cor-pulmonale (COR-P), right and left ventricular dysfunction. Echocardiography provides a rapid, noninvasive, portable, and accurate method to evaluate cardiac functions. Early diagnoses and intervention for cardiac comorbidities would reduce mortalities.

Materials and Methods:

A cross-sectional study. Total 50 patients of moderate to severe COPD according to GOLD guidelines were taken from Department of Respiratory Medicine, Smt. B. K. Shah Medical Institute and Research Centre, Vadodara. All patients underwent investigations such as chest X-ray PA view, ECG, and spirometry followed by two-dimensional echocardiography.

We investigated 49 males and 1 female patients ranging from 35 to 80 years of age. Twenty-nine individuals were of moderate COPD and twenty-one of severe COPD. Of these cases 29 had left ventricular diastolic dysfunction (LVDD) changes, 24 were diagnosed with PH and 16 had changes of COR-P. The study showed the linear relation between the severity of LVDD, PH, and COR-P with the severity of COPD.

Conclusion:

Our study put emphasis on early cardiac screening of all COPD patients which will be helpful in the assessment of the prognosis and will further assist in identifying the individuals likely to suffer increase morbidity and mortality.

INTRODUCTION

Chronic obstructive pulmonary disease (COPD) is a global health issue with smoking being the most important risk factor. By 2020, it will be the third most leading cause of mortality and fifth leading cause of morbidity in the world.[ 1 , 2 ] There is a crude estimate of about 30 million people in India suffering from COPD, and the death rate is among the highest in the world, data suggests that about 556,000, i.e. (>20%) of total 2,748,000 die in India annually.[ 3 , 4 ]

COPD is characterized by chronic airflow limitation and a range of pathological changes in the lungs. In addition, COPD presents significant extrapulmonary effects and is associated with important comorbidities that may contribute to the disease severity. Chronic airflow limitation is associated with an abnormal inflammatory response of the lungs to noxious particles or gases, particularly cigarette smoke.[ 5 ]

COPD affects pulmonary blood vessels, right ventricle, as well as left ventricle leading to the development of pulmonary hypertension (PH), cor-pulmonale (COR-P), right ventricular dysfunction, and left ventricular dysfunction. Ischemic heart disease is one of the main causes of mortality in COPD.[ 6 ] Co-existence of both diseases is very common and has diagnostic, therapeutic, and prognostic implications.[ 7 , 8 ] Chronic bronchitis alone increases the risk of coronary deaths by 50%. Reduced ratio of forced expiratory volume in 1 s (FEV1) to forced vital capacity (FVC) is also an independent risk factor for coronary events, increasing the risk by 30%. With every 10% decrease in FEV1, all-cause mortality increases by 14% and an increase in cardiovascular mortality by 28%.[ 9 ] In more advanced COPD, cardiovascular diseases account for 20-25% of all deaths.[ 10 ]

Left ventricular diastolic dysfunction (LVDD) is defined as the inability of the ventricle to fill to a normal end-diastolic volume, both during exercise as well as at rest, while left atrial pressure does not exceed 12 mmHg.[ 11 , 12 , 13 ] LVDD is a common co-phenomenon in COPD.[ 14 , 15 ] Abnormal left ventricular function is seen in COPD due to many factors such as hypoxia, acidosis, ventricular interdependence, lung hyperinflation, and distension.

Left ventricular systolic dysfunction (LVSD) is a disorder characterized by failure of the left ventricle to produce adequate output despite an increase in distending pressure and end-diastolic volume.

PH is an increase of blood pressure in the pulmonary artery, pulmonary vein, or pulmonary capillaries, together known as the lung vasculature.

PH is defined as systolic pulmonary artery pressure (sPAP) >30 mmHg and it is classified into mild, moderate, and severe grades as sPAP 30-50 mmHg, sPAP 50-70 mmHg, and sPAP >70 mmHg, respectively.[ 16 , 17 ]

COR-P is defined as an alteration in the structure and function of the right ventricle caused by a primary disorder of the respiratory system. PH is the common link between lung dysfunction and the heart in COR-P. COR-P can develop due to various cardiopulmonary diseases. COR-P usually has a slow and chronic progression, but acute onset and life-threatening complications can occur.[ 18 ]

Echocardiography provides a rapid, noninvasive portable, and almost accurate method to evaluate the right ventricle function, right ventricular filling pressure, tricuspid regurgitation, left ventricular function, and valvular functions.[ 19 ] It has been studied that echocardiography measured pulmonary arterial pressure closely correlates with pressure measured by right heart catheterization.[ 20 , 21 ]

This study was undertaken to evaluate cardiac function with echocardiography in COPD patients which may further help to assess the prognosis and assist in identifying the individuals likely to suffer increase morbidity and mortality.

MATERIALS AND METHODOLOGY

This was a cross-sectional study. Consecutive 50 diagnosed moderate to severe COPD patients according to GOLD guideline (postbronchodilator FEV1/FVC ratio <70% predicted, moderate COPD [50% ≤FEV1 <80% predicted], severe COPD [FEV1 <50% predicted]), respectively have been taken for the study at Dhiraj Hospital, Smt. B. K. Shah Medical Institute and Research Centre, Piparia, Vadodara. The subject included between the age of 35-80 years with informed and written consent.

The patients which were not made as a part of the study were the one with, known diagnosis of respiratory problems such as pneumonia, tuberculosis, bronchial asthma, interstitial lung disease, carcinoma lungs, and other lung pathologies.

The other category of patients who were excluded had a history of cardiac diseases like ischemic heart disease, rheumatic heart disease, valvular heart diseases, congenital heart disease, and others. Patients who were immune compromised and suffering from (HIV, diabetes mellitus, carcinoma, systemic lupus erythematosus, and other immunosuppressive diseases) were also considered as exclusion criteria for the study.

All the patients selected were asked for the detailed history of respiratory as well as cardiovascular symptoms and were clinically examined for the signs of ventricular hypertrophy, cardiomegaly, PH and/or heart failure.

Patients were investigated for routine investigations such as complete blood count, renal functions, randomized blood sugar and further for a chest X-ray, electrocardiography, and two-dimensional (2D)-echocardiography.

2D-echocardiography was done by a VIVID 7 model of GE healthcare system with a multi-frequency probe with a range of 2–4.3 MHz both 2D and M-mode studies were done. Echo was done to review the pericardium, valvular anatomy and function, both sided chamber size and cardiac function.

Pulmonary hypertension

It was defined in this study as sPAP ≥30 mmHg.[ 16 ] This value was chosen according to the definition of PH. PH was classified into mild, moderate, and severe category as sPAP 30-50, 50-70, >70 mmHg, respectively (using Chemla formula, mean pulmonary arterial pressure (MPAP) =0.61 PASP +2 mmHg and putting value of 25-35, 35-45, and >45 mmHg of MPAP for mild, moderate, and severe PH, respectively).[ 17 ]

Measures of right ventricular functions

Right ventricle dimension was measured by M-mode echocardiography, and right ventricular dilation or COR-P was said to be present when it exceeded the normal range of 0.9-2.6 cm. Right ventricle contractility was also noted, and right ventricular systolic dysfunction was said to be present when it was hypokinetic.

Measures of left ventricular functions

E/A = diastolic filling of left ventricles usually classified initially on the basis of the peak mitral flow velocity of the early rapid filling wave (E), peak velocity of the late filling wave caused by atrial contraction (A). In normal subjects, LV elastic recoil is vigorous because of normal myocardial relaxation, therefore, more filling is completed during early diastolic, so LVDD is said to be present when E/A is <1.3 (age group 45-49 years), <1.2 (age group 50-59 years), <1.0 (age group 60-69 years), and <0.8 (age group ≥70 years).[ 22 ]

Statistical analysis: The descriptive statistical analysis of data has been done. The age and sex distribution of all patients, their body mass index (BMI), severity of COPD, echocardiography findings, the frequency of COR-P and its relation to COPD has been represented graphically.

Correlation between the cardiac parameters on echocardiography findings and pulmonary parameters on spirometry findings have been done to find out the relation and to estimate the risk of morbidity.

The mean and standard deviation (SD) of FEV1 and PH of all the patients has been calculated along with Pearson correlation value.

We investigated 49 males and 1 female patient in the age group of 35–80 years. Mean BMI was 19.59 kg/m 2 . Out of 50 patients, 24 (48%) patients were underweight. The mean pack years for smoking were 31.33. On the basis of severity, the study showed 58% of moderate COPD and 42% of severe COPD patients. Mean ± SD calculated for FEV1 was 49.05 ± 14.61.

The most common finding on echocardiography was LVDD 29/50 (58%), next to which was PH 24/50 (48%), followed by LVH 4/50 (8%) and LVSD 3/50 (6%). The study showed 7/50 (14%) of normal cases.

Of 24 patients of PH, there were 16 (66.66%), 02 (8.33%), and 06 (25.0%) patients of mild, moderate, and severe respectively. Mean ± SD calculated for PH ( n = 50) was 35.59 ± 15.47.

Of 29 patients with LVDD, 20(68.96%) were of Grade 1, 8 (27.58%) of Grade 2, and 01 (3.44%) of Grade 3.

The severity of PH, COR-P, and LVSD were increasing with increasing severity of COPD as shown in Table 1 and Figure 1 . To conclude, except LVDD and LVH all other cardiac changes increased with increase of COPD severity. In details, if we note that Grade 1 LVDD is more common in moderate COPD cases but Grade 2 and Grade 3 LVDD in severe COPD cases shown in Figure 2 .

Comparison between severity of chronic obstructive pulmonary disease and cardiac changes

Correlation graph of chronic obstructive pulmonary disease and cardiac changes

Correlation graph of chronic obstructive pulmonary disease and left ventricular diastolic dysfunction

Figure 3 explains the relation of FEV1 to COR-P suggesting that moderate COPD, severe, and very severe COPD has a direct linear relation to COR-P.

Frequency of cor-pulmonale in relation to forced expiratory volume in 1 s

Figure 4 explains the linear relation between FEV1 and mean PH.

Correlation of forced expiratory volume in 1 s with means pulmonary hypertension

Figure 5 explains the correlation between FeV1 and PH in a form of scatter diagram. Pearson's correlation coefficient (r) value calculated is −0.45, i.e., with an increase in FEV1 there is fall in mean PH.

Correlation between pulmonary hypertension and forced expiratory volume in 1 s (scatter chart)

There are various cardiac changes seen in the patients suffering from COPD. Right-sided cardiac dysfunction and PH are one of the main established complications described in many studies done worldwide. Our study has added a little more strength to the various studies by proving the changes of PH and COR-P in COPD and by direct correlation between their severities. The Pearson correlation coefficient value of −0.45 is suggestive of mild negative correlation. This negative value describes that with every decrease in FEV1 there is an increase in PH values. Cigarette smoking and other exposure factors lead to inflammatory changes which disrupt the vascular pulmonary endothelium and on the other hand changes of chronic bronchitis and emphysema leads to chronic hypoxic conditions which result into pulmonary artery remodeling and vasoconstriction. The other mechanism leading to the damage is the change in intrinsic pulmonary vasodilator substances such as prostacyclin synthase, decrease in endothelial nitric oxide synthase and increase in endothelial 1. As a result, we see remodeling, changes in respiratory mechanics and also, increase in blood viscosity. All these factors lead to PH. PH increases the afterload of right ventricle and increase of right ventricular work as well. If we summarize the whole mechanism of COPD, hypoxic vasoconstriction, and PH will result into right ventricular hypertrophy and even its dilatation giving a clinical presentation of the right heart failure.

There are no exact data of PH prevalence in COPD; pulmonary artery pressures were seen elevated in about 20–90% of patients when measured by right heart catheterization, with evidence of changing severity in pulmonary hemodynamics with the severity in airflow obstruction.[ 23 ] Two studies have shown an abnormal increase in MPAP (Ppa) in COPD of 0.4-0.6 mmHg per year. These studies illustrate that PH in COPD progresses slowly and occur in mild as well as severe forms of disease.[ 24 , 25 ]

Several studies have demonstrated the prognostic value of PH in COPD patients. Severe the PH more poor the prognosis, even in patients of COPD receiving long-term oxygen therapy. In one of the studies showing the 5 years survival rate were 50% in patients with mild PH (20-30 mmHg), 30% in those with moderate and severe PH (30-50 mmHg), and 0% in small group of patients suffering from severe PH (>50 mmHg). This study finding reveals 48% patients of the various severity of COPD has findings for PH that is almost similar to the previous studies. The frequencies of PH in moderate and severe COPD were 33.33% and 66.66%, respectively which is comparable to other study in which findings were 43% and 68%, respectively.[ 26 ]

In our study, there is direct linear correlation seen between PH and severity of COPD (FEV1). Previous studies showed the frequency of severe PH in COPD about 1-3%[ 27 , 28 ] but in our study, it has shown a high rise of 12% which could be explained as the study included only moderate and severe COPD cases.

COR-P was present in 32% of patients in our study. Approximately, about 25% patients of COPD develop COR-P.[ 29 ] One of the autopsy study showed 40% patients of COPD had COR-P.[ 23 ] In comparison, the results are matching to our study.

The cause of LVDD in COPD patients could be due to chronic hypoxemia leading to the changes in myocardial relaxation, distension, and lung hyperinflation making the parietal pleura stiff and similarly the walls of cardiac fossa adding the load to the walls of ventricle and also due to ventricular interdependence. In our study, LVDD was present in 58% of patients as compared to 47.5% seen in the study done by Gupta et al .[ 23 ]

One of the limitations of our study was a small size, the other factors being not able to perform the right sided heart catheterization or employ transoesophageal echocardiography. Further well designed cohort studies and use of future three dimensional echocardiography with optimal sample size will be helpful in defining the role of echocardiography in COPD patients.

The study shows high prevalence of cardiac co-morbidities such as PH, COR-P, LV dysfunction in COPD patients. The severity of complications increases with severity of COPD and makes a linear relation. This relation was also seen in Grade 2 and Grade 3 LV dysfunction and was not seen in Grade 1.

Hence, our study put emphasis on cardiac screening of all COPD patients.

Financial support and sponsorship

Conflicts of interest.

There are no conflicts of interest.

Acknowledgment

I am very thankful to Dr. Mayur Adalja sir (M. D Respiratory Medicine) for his efforts, guidance and help all through my subject of research.

• You are here :
• Departments
• Respiratory Medicine Department

Department of Respiratory Medicine

Academics extension and research, dissertation.

1.	Dr. Ajinkya Mhase	MD(Pulmonary Medicine)	Comparison of the efficacy of standard rehabilitation breathing technique Vs. efficacy of Yogic breathing in moderate to severe C.O.P.D. patients	Dr. Tushar Sahasrabudhe
2.	Dr. Kundan Mehta	MD(Pulmonary Medicine)	To evaluate how much of post TB OAD can be attributed to TB as a possible etiology..	Dr. Tushar Sahasrabudhe
3.	Dr. Prashant Kumar Singh	MD(Pulmonary Medicine)	Pre-perative Spirometry and Post- Operative Pulmonary Complications In Patients undergoing Elective Upper Abdominal Surgeries	Dr. Vinay Dharmadhikari
4.	Dr.Sumit Kumar	MD(Pulmonary Medicine)	“Comparison of yield of ziethi-neelsen (ZN) staining by additional two sputum examinations, examination of sputum obtained after nebulization with Salbutamol and bronchoalveolar lavage (BAL), cases of sputum smear negative pulmonary tuberculosis.”	Dr. Vinay Dharmadhikari
5.	Dr. Ajay Kattakkayam	MD(Pulmonary Medicine)	Correlation ranges of normal BMI with lung function tests.	Dr.Tushar Sahasrabudhe
6.	Dr. Avinash Chauhan	MD(Pulmonary Medicine)	Role of Pleuroscopy in the diagnosis and management of pleural effusions: A prospective study.	Dr. Meena Hingorani
7.	Dr. Sowmya Attipatla	MD(Pulmonary Medicine)	“Effect of supplementation of vitamin D on outcome of treatment of Tuberculosis	Dr.Tushar Sahasrabudhe
8.	Dr. Ahmar Javid	MD(Pulmonary Medicine)	Study of Sleep pattern in Patients COPD	Dr. Vinay Dharmadhikari
9.	Dr. Fouzia Ajani	MD(Pulmonary Medicine)	Study of Role of spirometry in Quitting Smoking	Dr. Meena Hingorani
10.	Dr. Arpan Dhoka	MD(Pulmonary Medicine)	Evaluation of FVC and FEV1 as predictors of Ischemic Heart Disease (IHD) in patients of COPD	Dr. Tushar Sahasrabudhe
11.	Dr. Kirti Yadav	MD(Pulmonary Medicine)	Assessment of respiratory tract inflammation with overnight exposure to mosquito repellents mats in COPD patient and normal individual	Dr. Tushar Sahasrabudhe
12.	Dr. Shailesh Meshram	MD(Pulmonary Medicine)	Correlation between extent of air trapping due to small airways involvement on expiratory HRCT scan and pulmonary function tests in COPD	Dr. Vinay Dharmadhikari
13.	Dr. Harshad Azeem E.K.	MD(Pulmonary Medicine )	To evaluate the efficacy & safety of IPFT in case of untrained tubercular pleural effusion.	Dr. Tushar Sahasrabudhe
14.	Dr. Gitartha Baruah	MD(Pulmonary Medicine )	Study of Usage Inhalation Devices and Inhalation Technique in Bronchial Asthma and Chronic Obstructive Pulmonary Disease.	Dr. M. S. Barthwal
15.	Dr. Sourabh Jain	MD(Pulmonary Medicine )	Study of clinical, Radiological functional profile of patient of ILD attending tertiary care Centre in western India.	Dr. Vinay Dharmadhikari
16.	Dr. Shubhi Singhal	MD(Pulmonary Medicine )	Evaluation of asthma management and control in adults in and around Pune city of Maharashtra.	Dr. M. S. Barthwal
17.	Dr. Nirmala Muthukaruppan Ananthi	MD(Pulmonary Medicine )	Etiological spectrum of bronchiectasis in Indian patients.	Dr. Tushar Sahasrabudhe
18.	Dr Sajin Sunny Mathew	MD(Pulmonary Medicine )	Assessment of prevalence and risk factors for associated coronary artery disease in patients of chronic obstructive pulmonary disease	Dr M.S. Barthwal
19.	Dr Suvarna Lakshmi Kalli	MD(Pulmonary Medicine )	Role of blind closed pleural biopsy in undiagnosed cases of pleural effusion	Dr M.S.Barthwal
20.	Dr Amal Raj	MD(Pulmonary Medicine )	Assessment of respiratory health in flour mill worker	Dr Tushar Sahasrabudhe
21.	Dr Haadi Nizar Ahammed	MD(Pulmonary Medicine )	Use of sublingual bacterial lysates in stables COPD- a case control study	Dr Tushar Sahasrabudhe
22.	Dr Priyanka Singh	MD(Pulmonary Medicine )	Risk factors and clinical profile of chronic obstructive pulmonary disease in females	Dr Vinay Dharamadhikari
23.	Dr Sakshi Dubey	MD(Pulmonary Medicine )	Study of bronchoalveolar lavage in sputum smear and cbnaat negative of presumptive pulmonary tuberculosis	Dr Nitin Gaikwad
24.	Dr Ashwin Ramesh CB	MD(Pulmonary Medicine )	Clinical, radiological and microbiological profile of community acquired pneumonia in adults	Dr M S Barthwal
25.	Dr Ayesha Chaturvedi	MD(Pulmonary Medicine )	Assessment of the co-existence of chronic bronchial asthma and allergic rhinintis in adults	Dr Mahavir Bagrecha
26.	Dr Kiran Balani	MD(Pulmonary Medicine )	Assessing effectiveness of cheap and practical ways of sputum disinfection for pulmonary tuberculosis patients in home scenario	Dr Tushar Sahasrabudhe
27.	Dr Manjush RM	MD(Pulmonary Medicine )	Utility of peak flow meter in diagnosis of bronchial asthma	Dr M S Barthwal
28.	Dr Mukul Saini	MD(Pulmonary Medicine )	Efficacy and safety of providone iodine pleurodesis versus tetracycline pleurodesis	Dr Tushar Sahasrabudhe
29.	Dr Prathyusha Alakunta	MD(Pulmonary Medicine )	To assess the clinical profile of suspected/proven cases of TB cervical lymphadenitis and the role of CBNAAT in diagnosis	Dr Nitin Gaikwad
30.	Dr Omkar Konjeti	MD(Pulmonary Medicine )	Correlation of six-minute walk test and COPD assessment test(CAT) scores with spirometric indices in chronic obstructive pulmonary disease patients	Dr Nitin Gaikwad
31.	Dr Srihitha Kakani	MD(Pulmonary Medicine )	Assessment of bacterial colonization in stable patients of chronic obstructive pulmonary disease	Dr Sachinkumar Dole
32.	Dr Harsha Elizabeth Meleth	MD(Pulmonary Medicine )	Prevalence of asthma, chronic obstructive airway disease overlap in patients with chronic airflow obstruction	Dr M.S. Barthwal
33.	Dr Vishnu Prabhakar	MD(Pulmonary Medicine )	Clinical and radiological correlation in covid -19 patients	Dr M.S.Barthwal
34.	Dr Harshmeet Singh Gujral	MD(Pulmonary Medicine )	Study of disease sequelae in patients who suffered from covid-19	Dr Tushar Sahasrabudhe
35.	Dr Adithya Vivek Sundar	MD(Pulmonary Medicine )	Study of obstructive airway diseases that can be attributed to tuberculosis	Dr Tushar Sahasrabudhe
36.	Dr Muthu Ganesh	MD(Pulmonary Medicine )	Etiological, clinic-radiological and microbiological profile of exudative pleural effusion	Dr Nitin Gaikwad
37.	Dr Sona Mohan	MD(Pulmonary Medicine )	Correlation between 6 minute walk test and diffusion capacity of lung for carbon monoxide(DLCO) in diffuse parenchymal lung diseases(DPLD)	Dr Nitin Gaikwad
38.	Dr K R Senthamizh	MD(Pulmonary Medicine )	To study the prevalence of metabolic syndrome on copd and to correlate with clinical profile in tertiary hospital	Dr Mahavir Bagrecha
39.	Dr Robin Singh Bhatti	MD(Pulmonary Medicine )	Assessment of airway disease using spirometry in traffic policeman exposed to environmental pollution	Dr Sachinkumar Dole
	Dr Vineeth Anurag	MD(Respiratory Medicine)	Broncho alveolar lavage cytology in diffuse parenchymal lung diseases	Dr M S Barthwal
	Dr Rhea Gandhi	MD(Respiratory Medicine)	Assessment of obstructive airway diseases in paramedical and sanitation workers in tertiary care hospital	Dr M S Barthwal
	Dr Sidhaant Nangia	MD(Respiratory Medicine)	Evaluating efficacy of various sputum disinfectants for MDR TB patients and its correlation with genetic mutation	Dr Tushar Sahasrabudhe
	Dr Mithun Nilgiri K	MD(Respiratory Medicine)	socio-economic and emotional challenges faced by patients suffering from drug resistant tuberculosis	Dr Tushar Sahasrabudhe
	Dr Arun Balan	MD(Respiratory Medicine)	Utility of ratio of asenosine deaminase and serum c-reactive protein in differentating parapneumonic , tuberculosis and malignant effusions	Dr Sachinkumar Dole
	Dr Ansari Islahuzzama Salahuddin	MD(Respiratory Medicine)	To study etiological profile and treatment outcome in patients with loculated pleural effusion presenting at tertiary centre	Dr Sachinkumar Dole
	Dr Spandana Chaudhury	MD(Respiratory Medicine)	To Study the adverse effects in drug resistant tuberculosis patients taking drug resistant tuberculosis treatment	Dr Mahavir Bagrecha
	Dr. M Manosri	MD(Respiratory Medicine)	To study the clinical and radiological profile of idiopathic pulmonary fibrosis in patients in tertiary care centre in Pune	Dr M S Barthwal
	Dr .Vasu Agarwal	MD(Respiratory Medicine)	To study the clinical and etiological profile of pulmonary hypertension	Dr M S Barthwal
49.	Dr. Atulya Anand	MD(Respiratory Medicine)	KABP(Knowledge, Attitude, Beliefs and practices) evaluation of asthmatics and assessing the impact of patient education and device training	Dr Tushar Sahasrabudhe
50.	Dr Brahmansh Singh	MD(Respiratory Medicine)	To study the prevalence of latent tuberculosis infection and incidence of new infection among people with long term exposure to hospital environment in comparison with those unexposed	Dr Tushar Sahasrabudhe
51.	Dr. Pratiksha Dutta	MD(Respiratory Medicine)	Clinical ,radiological and microbiological, profile of Bronchiectasis in adults in a tertiary care hospital	Dr. Sachinkumar Dole
52.	Dr Hiral Ramnani	MD(Respiratory Medicine)	Clinical, radiological microbiological profile of ventilator associated pneumonia in adults in tertiary care hospital in India-an observational study	Dr. Sachinkumar Dole
53.	Dr Sneha Sanjay Deore	MD(Respiratory Medicine)	Clinical Spectrum and Spirometry assessment of patients with post tubercular lung diseases	Dr. Sachinkumar Dole
54.	Dr. Lekshmi R. S	MD(Respiratory Medicine)	Correlation of BMI with Asthma control, quality of life and airway obstruction severity in patients of bronchial asthma visiting tertiary care hospital in Pune	Dr. Mahavir Bagrecha
55.	Dr. Parna Chakraborty	MD(Respiratory Medicine)	Study of usage of spirometry in diagnosing asthma and COPD by doctors in and around Pune city of Maharashtra, India	Dr. M S Barthwal
56.	Dr. Geedhara Harsha Vardhan Reddy	MD(Respiratory Medicine)	Study of management of diffuse parenchymal lung disease by doctors in and around Pune city of Maharashtra, India	Dr. M S Barthwal
57.	Dr. Ronak Agarwal	MD(Respiratory Medicine)	Public spitting in the city and public opinion about it	Dr. Tushar Sahasrabudhe
58.	Dr. Balamoni Vinay Kumar Goud	MD(Respiratory Medicine)	Lung biopsy in interstitial lung disease and its clinico –radiological and	Dr. Tushar Sahasrabudhe

• List of Publications
• Research Outcomes
• PO & CO Analysis (UG and PG)
• Alumni Placement
• Wall Magazine
• Teaching Programme
• Integrated Teaching
• Dissertations
• Achievements and Awards (Faculty, PG and UG Students)
• Conferences/ CMEs/ Workshops Organized
• Conferences/ CMEs/ Workshops Attended by Faculty and Students
• Best Practices
• Other Information

Dr. D. Y. Patil Medical College, Hospital & Research Centre, Sant Tukaram Nagar, Pimpri, Pune 411018 Maharashtra, India.

Social Media

• Non Visual Desktop Access(NVDA)
• Shortcut Keys

Important Link

• Privacy Policy
• Terms and Conditions

Copyright ©2024 | All Rights Reserved By Software Development Cell, Dr. D. Y. Patil Vidyapeeth, Pune

Make An Appointment

Powerpoint Presentations

• Thesis Topics
• Patient Education Materials

Welcome to largest collection of PowerPoint presentations and patient education materials in Pulmonary Medicine.

Our Collection Contains more than thousands of PowerPoint Presentations, patient education materials, e-books, journals and website links, post graduate syllabus, model question papers, thesis topics, various guidelines and diagrams covering various fields of Pulmonary Medicine. If you are going to prepare a seminar you can compare with multiple similar presentations given here, sometimes if you are busy you can use these slides as such without any modification or with slight modification. To download files right click on the link and select save target as or save link as. But in most browsers just a single left click will automatically start downloading. If any of you have a good personal PowerPoint presentations Email us we will upload it here.

Recent Post

• Lung Cancer
• Sleep Disorders

HIV -Pulmonary Manifestations

• Occupational Lung Diseases

Lung Transplantation

Inhalational devices, popular articles, lung & other systems, chest physiotherapy, hypertension, intercostal drainage, clinical examination, air pollution, critical care & ventilators.

• Asthma, Allergy and Immunology
• Interstitial Lung Diseases
• Tuberculosis
• Pulmonary Vascular Diseases
• Pleural Diseases
• Suppurative Lung Diseases
• Drug Induced Lung Diseases
• Chest wall, Diaphragm and Mediastinal Disorders
• Respiratory System Anatomy and Physiology

Android Medical Apps

Calculate by qxmd, diseases dictionary, abg interpreter, medical tools.

Google+ -->

	Facebook	Facebook
	Linkedin
Contact details -: Email-: [email protected], Phone-: +91 7034564871 Personal Portfolio: www.drtinkujoseph.com

Medical Mnemonics

© 2015-2018 Copyright lunghouse.com . All Rights reserved. Designed & Hosted by Live Creation

Home > MAHE Student Work > KMCMLR

Kasturba Medical College, Mangalore Theses and Dissertations

Theses/dissertations from 2021 2021.

“The Impact of Self-Stigma of Seeking Help and Perceived Social Support on Burnout among Clinical Psychologists” , Aavrita A

The impact of self-stigma of seeking help &percieved social support on burnout among clinical psychologists. , Aavrita .

Immediate Effects of Novel Hand Rehabilitation Board on Fine Motor Skills in Children with Cerebral Palsy. , Romita Fernandes. Abraham

"COMPARISON OF THREE SCORING CRITERIA TO ASSESS RECOVERY FROM GENERAL ANAESTHESIA IN THE POST-ANAESTHESIA CARE UNIT- A LONGITUDINAL OBSERVATIONAL STUDY " , Shagun Aggarwal

Comparative predictive validity of Alberta Infant Motor Scale and Infant Neurological International Battery in Low Birth Weight Infants- A Prospective Longitudinal Study. , Polisetti Siva Sai Anand

Antagonistic Asynchrony in Muscle Recruitment Pattern of Forward Reach Movement In Children With Cerebral Palsy. , Sanya Anklesaria

Muscle fatigue response of rotator cuff muscles in sitting and standing postures , Lisanne Aranha

Effectiveness of static weight bearing versus modified constraint induced movement therapy on improving hand function in hemiplegic cerebral palsy- A Randomized Clinical Trial. , Ruth Bavighar

How informed are our patients about generic medicines? – A study from coastal South India , Darshan BB

Morphological variants of the human spleen, a cadaveric study , Murlimanju BV

Association between cervical breast cancer and Diabtetes mellitus among women seeking health care in tertiary hospitals od south India: A cross sectional study , Pratik Kumar Chatterjee

Carcinoma Breast in among Women with Diabetes Mellitus: A Case Control Study , Pratik Kumar Chatterjee

Perception of Empathy among medical students: A cross sectional study , Pratik Kumar Chatterjee

CLINICOMYCOLOGICAL PROFILE OF DERMATOPHYTOSIS IN A TERTIARY CARE HOSPITAL IN SOUTH INDIA , Adyashree Dalai

Study of outcome of Ponseti technique of management for idiopathic clubfoot in a tertiary center in south India , Lulu Damsas

Comparative study of emotional labour &burnout on life satisfaction among school teachers across different educational settings , Meghana Dharampalan

“Comparative Study of Emotional Labor and Burnout on Life Satisfaction Among School Teachers Across Different Educational Settings” , Meghana V. Dharmapalan

“Relationship Between Sexual Fantasy, Sexual Communication, Personality Traits and Sexual Satisfaction in Married Individuals” , Rhea Dhir

Comparing the efficacy of USG guided supraclavicular brachial plexus block with or without intercostobrachial nerve block for forearm surgeries – an observational study , DIKSHA D’MELLO

Does Quality of Sitting influence Functional Mobility in Cerebral Palsy? A cross-sectional study , Kaiorisa N. Doctor

Factors effecting gait velocity in osteoarthritis knee-An observational study. , Lisha Gretal D’silva

Effect of Inspiratory Muscle Training on Pulmonary Function, Functional Capacity, Quality Of Life And Length Of Stay in individuals undergoing Cardiac Surgery , Fiona Verdine Dsouza

Relationship of Academic Resilience with Self-Efficacy, and Perceived Social Support; Among Civil Service Aspirants , Neha Eldho

EFFICACY, FEASIBILITY, AND SAFETY OF PERCUTANEOUS IMAGE-GUIDED CATHETER DRAINAGE OF THORACIC, ABDOMINAL, AND PELVIC FLUID COLLECTION , Aishwarya Gadwal

Comparison of efficacy of two different bolus doses of norepinephrine as prophylac-tic to prevent post-spinal hypotension during elective caesarean section , PRANATHI GARAPATI

Trends in Frailty and its Associated factors in Community Dwelling Elderly Indian Population during COVID-19 Pandemic- A Prospective Analytical Study , Karan Gautam

Speech Sound acquisition in some south Indian Dravidian languages: A systematic review , Jesica George

Comparison of Femoral nerve block with Dexmedetomidine and Adductor canal block with Dexmedetomidine for postoperative analgesia for Total Knee Arthroplasty . , NEHA GEORGE

Assessment Of Cardiovascular Risk Factors In Patients With Osteoarthritis Knee , Sagar Goel

Effectiveness of Intermittent Cervical Traction with and without Neural Mobilization in Discogenic Cervical Radiculopathy , Aditi Goyal

Study of maternal and cord blood vitamin B12 levels with anthropometry in term neonates born to normal and malnourished mothers: a hospital based cross sectional study , Sugapradha a. GR

Development of a Questionnaire to Determine the Intervention and Service Delivery Practices of Speech-Language Pathologists for Children with Speech Sound Disorders in India , Shaily Gupta

Relationship between Physical Activity, Objective Sleep Parameters and Circadian Rhythm in Patients with Head and Neck Cancer receiving Chemoradiotherapy- A Longitudinal Study , Rachita Gururaj

“Emotional Contagion, Perceived Stress and Coping Strategies Among Nurses” , Saumya Hariharan

Assessment of knowledge and belief about stuttering among undergraduate medical students , Anushree Harihar

Association of serum lipid levels and other systemic risk factors with retinal hard exudates in diabetic retinopathy patients. , Harshita Mukesh Hiran

Assessment of risk of Diabetes Mellitus by using Indian Diabetes Risk Score among Housekeeping staff , Ramesh Holla

“Emotional Intelligence, Self-compassion, and Life-Satisfaction In Clinical Psychologists” , Vania Jacob

UPPER-CROSSED SYNDROME AND DISABILITY IN SHOULDER ADHESIVE CAPSULITIS. , Aishwarya Jaideep

Study to assess the role of doppler ultrasound in evaluation of arteriovenous hemodialysis fistula and the complications of hemodialysis access , Ishank Jain

Relationship between burnout compassion fatigue, work environment & mindfulness in medical residents , Pranay Javeri

“Relationship Between Burnout, Compassion Fatigue, Work Environment and Mindfulness in Medical Residents” , Pranay Harichandra Javeri

“Dating Anxiety in Emerging Adults” , Jisha V. Jayaprakash

“Relationship Between Tolerance for Disagreement and Mindfulness in Married Males and Married Females” , Jahnavi Jha

Antibiotic usage and susceptibility patterns in Uncomplicated UTI in a Tertiary Hospital in South India , Christy John

Association of bed rise difficulty scale with trunk impairment and functional scales among stroke patients , Leena G. John

Is there a correlation between Pediatric Berg Balance Scale and Centre of Pressure Excursion measured through Dual Axis Static Force Plate™ to assess Balance in Children with Spastic Cerebral Palsy and Typically Developing? , Niharika Joshi

Comparison of Sensory Processing Responses in Cerebral Palsy Subtypes and Typically Developing Children (7-36 months): A Cross Sectional Study. , Archana Antony K

‘A study on the Role of Learned Helplessness, Selfefficacy and Perceived Social Support in Determining Resilience in Parents of Children with Neurodevelopmental Disorders’ , Benaisha Khurshed Katrak

A study of correlation of maternal serum zinc levels with breast milk and cord blood of late preterm neonates , Rashmi Katti

Correlation of histopathology and direct immunofluorescence findings in clinically diagnosed prurigo nodularis , Haritha K

Difference in proximal femur loading due to muscle activity during partial weight bearing and NWB standing- A cross-sectional study. , Smital Kshirsagar

Effect of Sesamol on neurobiochemical changes in diet induced (DIO) obesity model of Zebra fish (Danio rerio) , Rashmii K.S.

Importance of integration of medical ethics with undergraduate medical curriculum- Instructors and student’s perspectives. , Rashmii K.S.

Long-term potentiation (LTP): A simple yet powerful cellular process in learning and memory , Rashmii K.S.

Parkinson's Disease Overview: Alternative Potential Curcumin Treatment, Current Treatment and Prevalence Among Ethnic Groups , Rashmii K.S.

Smart brain of India vs. tricky drugs , Rashmii K.S.

The Role of Professionalism and Ethics Training: Instructor’s and Student’s perspectives in a medical College , Rashmii K.S.

Violence Against Doctors: A Qualitative Study On This Rising Predicament , Rashmii K.S.

Morphometric study of the gracilis muscle and its pedicles , Chettiar Ganesh Kumar

Comparative study of bed side tests to assess difficult airway in paediatric patients , S.Abinandha Kumar

Euphorbia thymifolia (Linn.)- A review on ethno pharmacological properties , Vasavi Kumblekar

COMPARISON OF KNOWLEDGE, ATTITUDE, AND PRACTICE TOWARDS THE USE OF SUNSCREEN IN DAILY LIFE BETWEEN FIRST -AND THIRD -YEAR MEDICAL STUDENTS , Aarushi Lall

‘Feminist Identity, Socio-cultural Attitude Towards Appearance, and Body Images issues in Emerging Adult Women’ , Sheena Lonappan

A novel approach to quantify the Dynamic Windlass Mechanism , Ishita Mahajan

METFORMIN VERSUS INSULIN IN THE MANAGEMENT OF GESTATIONAL DIABETES , Varikuti Manogna

Cognitive abilities among employed and unemployed middle-aged women – a systematic review , Aswini M

‘Emotional Intelligence, Job Satisfaction and Psychological Well-being Among Nurses’ , Chetna M

RELATIONSHIP OF COMPUTER AIDED DESIGN(CAD)-BASED PHOTOGRAMMETRY FOR FACIAL DYSFUNCTION WITH FACIAL GRADING SYSTEMS FOR BELL’S PALSY: A PROSPECTIVE OBSERVATIONAL STUDY , Ankita Mehendale

“Effect of Sensation Seeking and Anxious Traits on Suicidal Ideation Among Adults by Birth Order” , Haripriya G. M

Clinical & radiological assessment of intertrochanteric fractures treated with PFN A2 , Harish M

Effect of a home-based pulmonary rehabilitation programme on respiratory function, functional capacity, and quality of life in patients with chronic obstructive pulmonary disease , Vaibhavi Mhatre

Profiling Communication Characteristics of Individuals with Acquired Neuro-communication Disorder in a Tertiary Care Setup , Nikita Subudhi M

Relationship between weight bearing symmetry, trunk control and fear of fall amongst subjects with stroke: A cross sectional study , VIVIAN NEHAL MONIS

Lower extremity muscle recruitment pattern during sit to stand transfer in children with cerebral palsy as compared to typically developing children- a cross sectional study. , Kiran P. Nadgauda

Knowledge, attitudes and practices of Indian classical singers towards vocal healthcare , Raveena Muralidharan Nair

"Perspectives of Indian Speech Language Pathologists on Adolescent Language Assessment" , Rohana Muralidharan Nair

Effect Of Yoga On Perceived Stress And Pulmonary Function In High Stressed Postmenopausal Women , Vinodini NA

Refractory errors, blood groups & diabetes mellitus: A corrleative study in south Indian population , Vinodini NA

Comparison of Functional outcomes for displaced extra-articular distal radius fractures managed by Conservative versus Operative methods: A Prospective cohort study , Muhammed Ehsan Nazeer

COMPARATIVE STUDYOF THE EFFECTIVENESS OF VAPOCOOLANT SPRAY VERSUS EMLA®® CREAM IN REDUCING PAIN DURING INTRAVENOUS CANNULATION IN ADULT POPULATION , Sisla Nazer P

Assessment of attitude among public towards stuttering in a coastal city of Southern Karnataka , Prithvi N

"Severity assessment of acute pancreatitis using ct severity index and modified ct severity index: association with clinical outcomes and ranson’s criteria. " , GEETANJALI PARMAR

“The Effect of Culture Shock on Adjustment and Psychological Wellbeing Among College Going Students” , Akanksha Patra

‘Effect of Religiosity on Attitude Towards Euthanasia in Medical Students’ , Sumedha Pawar

Development Of A Questionnaire To Determine The Clinical Assessment Practices Of Speech-Language Pathologists For Children With Speech Sound Disorders In India , Prasila Elsa Philip

Correlation of oxidised LDL with oxidant and antioxidant enzymes in subjects with elevated LDL levels , Pooja p

Association of emotional intelligence of primigravida mothers with breastfeeding self efficacy in the early postpartum period and exclusive breastfeeding rates up to 6 months. , Priyanka Reddy p

Morphometric study of the Sartorius muscle and its vascular pedicles , M.D. Prameela

Comparison of the analgesic duration using ultrasound guided popliteal sciatic nerve block between diabetics with neuropathy and non-diabetics without neuropathy , GANESH PRASAD

Early follicular and Mid-luteal phase associated changes in Lower extremity Muscle strength , length and Agility in amateur female athletes – a Prospective Analytical study , Vishnu Priya

Assessment of mobile device based educational intervention on breastfeeding technique in multigravida mothers and its effect on early infant feeding pattern- A randomized controlled trial. , Keerthi Raj

THERMAL ULTRASOUND, MANIPULATION AND EXERCISE ON PAIN AND MOUTH OPENING IN CHRONIC TEMPOROMANDIBULAR JOINT DISORDER: A CASE REPORT , Suchita S. Rao

Correlation of Histopathology and Direct Immunofluorescence: Findings in clinically diagnosed Prurigo nodularis in a Tertiary care hospital , Haritha Reddy

EFFECT OF POSITIONING ON THE PAIN RESPONSE OF INFANTS VACCINATED WITH IPV AND PENTAVALENT (dtwp-HEPATITIS B-HEMOPHILUS INFLUENZA B) VACCINES , Sontosh Reddy

Assessment of the acceptable length of Right internal jugular central venous catheters. , Nivedhitha R

PRELEVANCE OF WORK RELATED DERMATOLOGICAL SYMPTOMS IN HEALTH CARE WORKERS IN COVID-19 ERA , Rana R

COMPARISON OF TWO ROUTINE FACIAL EXERCISE PROTCOLS FOR BELL’S PALSY- A RANDOMIZED CONTROLLED TRIAL , Stephanie Santiago

Profiling selected speech characteristics in individuals with Chronic Cough , Nawal Palakkal Sathar

Advanced Search

• Notify me via email or RSS
• Institutions
• Disciplines

Author Corner

Home | About | FAQ | My Account | Accessibility Statement

Privacy Copyright

Hon’ble Chancellor Vice Chancellor Registrar Principal Vice Principal Medical Superintendent

Anaesthesiology Anatomy Biochemistry Cardiac Anaesthesia Cardiology Cardio vascular & Thoracic Surgery Community Medicine Dermatology (Skin & VD) Emergency Medicine Endocrinology ENT, Head & Neck Surgery Forensic Medicine & Toxicology Gastroenterology

General Medicine General Surgery Interventional Radiology Medical Oncology Microbiology Nephrology Neonatology Neurology Neurosurgery Nuclear Medicine Obstetrics & Gynecology Ophthalmology Orthopedics Pathology

Public Health Research Unit Medical Education MCI Nodal Center Hospital Administration

Pediatrics Pediatric Neurology Pediatric Surgery Pharmacology Physical Medicine & Rehabilitation Physiology Plastic & Reconstructive surgery Psychiatry Radiation Oncology Radiology/Radio-diagnosis Respiratory/Pulmonary Medicine Surgical Oncology Urology

Under Graduate

Post graduate.

Post Doctoral Diploma Courses Public Health Ph.D Hospital Administration Fellowship Courses Allied Courses

Feedback Analysis 2015-20 Feedback Analysis 2021

Syllabus of Courses offered

Under Graduate Post Graduate Post Doctoral Fellowship Courses Ph.D Allied Courses

• KLE Advanced Simulation Centre & Clinical Skills Lab
• Cadaveric Skill Lab
• NIRF Prescribed Format
• JNMC NIRF 2018
• JNMC NIRF 2019
• JNMC NIRF 2020
• JNMC NIRF 2021
• JNMC NIRF 2022
• JNMC NIRF 2023
• JNMC NIRF 2024
• KLE Dr. PBK Hospital & MRC
• KLE Dr.PBK Hospital
• JNMC Women’s & Children’s Health Research Unit
• KLE Society
• Sports Complex
• Convention Center
• Musical Garden
• Shivalaya Temple
• Ganesh Temple
• Attendance Dashboard
• Scientific Society
• Student Association
• Kannada Balaga
• Institutional Ethics Committee
• Internal Complaint Committee
• Anti-Ragging
• Para Medical Course
• Capability Enhancement
• Faculty Login
• Student/Parent Login
• Dissertations
• M.B.B.S Phase III – Part-II

ONGOING DISSERTATION

	Dr. Arun George John	Dr. V A Kothiwale	“CORRELATION BETWEEN MEAN PLATELET VOLUME AND SEVERITY OF SEPSIS IN PATIENTS ADMITTED IN THE INTENSIVE CARE UNIT AT KLE DR. PRABHAKAR KORE HOSPITAL AND MEDICAL RESEARCH CENTRE, BELAGAVI – A ONE YEAR CROSS SECTIONAL STUDY .
	Dr. Yasoda Tushar Maldkar	Dr. V A Kothiwale	“ESTIMATION AND CORRELATION OF CLINICAL SIGNIFICANCE OF LIPOPROTEIN (A) AS A RISK FACTOR OF ATHEROSCLEROTIC VASCULAR EVENTS IN ELDERLY: A ONE YEAR CROSS-SECTIONAL STUDY IN KLE’S DR PRABHAKAR KORE HOSPITAL AND MEDICAL RESEARCH CENTRE, BELAGAVI.”
	Dr. Srijanee Das	Dr. V A Kothiwale	“CORRELATION BETWEEN SERUM URIC ACID & DISEASE ACTIVITY IN PATIENTS OF RHEUMATOID ARTHRITIS- A ONE YEAR CROSS SECTIONAL STUDY IN KLE’S DR. PRABHAKAR KORE HOSPITAL AND MEDICAL RESEARCH CENTRE, BELAGAVI.”
	Dr. Krishna  Reddy Singa Reddy	Dr. V G Somannavar	“EVALUATION OF CHANGES IN MEAN ARTERIAL PRESSURE AND PULSE PRESSURE FOLLOWING PASSIVE LEG RISING TEST AS INDEX AND PREDICTOR OF FLUID RESPONSIVENESS IN SEPTIC SHOCK PATIENTS.”
	Dr. Karmudi Prathyusha	Dr. V G Somannavar	“COMPARISON OF HAEMATOLOGICAL PARAMETERS IN ALCOHOLICS AND NON ALCOHOLICS.”
	Dr. Divya Killamsetty	Dr. Anwar Mujawar	“CORRELATION OF ABO BLOOD GROUPING AND OUTCOME IN SEPSIS PATIENTS ADMITTED IN INTENSIVE CARE UNIT AT KLE DR. PRABHAKAR KORE HOSPITAL AND MEDICAL RESEARCH CENTRE, BELAGAVI – A CROSS SECTIONAL BASED STUDY.”
	Dr.Snigdha  N Mazumdar	Dr. Rekha S Patil	“CORRELATION OF SERUM PROLACTIN LEVEL TO CHILD PUGH SCORING SYSTEM IN PATIENTS OF CIRRHOSIS OF LIVER IN A TERTIARY CARE HOSPITAL- A CROSS SECTIONAL STUDY”
	Dr. Nettem Sai Bhuvanesh	Dr. Rekha S Patil	“A ONE YEAR CROSS SECTIONAL STUDY ON ATTAINMENT OF TARGET BLOOD PRESSURE IN HYPERTENSIVES AT KLE HOSPITAL BELAGAVI.”
	Dr. E Vinayak	Dr. Madhav Prabhu	“CORRELATION OF SALIVARY GLUCOSE LEVEL WITH BLOOD GLUCOSE LEVEL IN DIABETES MELLITUS.”
	Dr.Vishal K	Dr. Arathi Darshan	“CORRELATION BETWEEN TRIGLYCERIDE GLUCOSE INDEX AND MICROVASCULAR COMPLICATIONS IN TYPE 2 DIABETES MELLITUS.”
	Dr.Saad Arshad Siddiqui	Dr. Jayaprakash A	“CLINICAL PROFILE, RISK FACTORS AND RESISTANCE PATTERN OF PATIENTS WITH VENTILATOR ASSOCIATED PNEUMONIA DUE TO ACINETOBACTER BAUMANNII IN INTENSIVE CARE UNITS
	Dr. Isha Desai	Dr. Naveen Angadi	“STUDY OF THYROID FUNCTION IN PATIENTS OF CHRONIC KIDNEY DISEASE.”
	Dr. Aakash Deep Singh	Dr. Dnyanesh Morkar	“ESTIMATION OF CARDIOVASCULAR DISEASE RISK PREDICTION BY ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (ASCVD) SCORE IN HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTED PATIENTS WHICH IS CROSS SECTIONAL STUDY IN KLE DR.PRABHAKAR KORE CHARITABLE HOSPITAL FOR 1YEAR OF DURTION..”
	Dr. Nagarjun Kamaneni	Dr. Dnyanesh Morkar	“AST TO PLATELET RATIO INDEX (APRI) IN PATIENTS WITH METABOLIC SYNDROME AND ITS RELATION WITH CARDIOVASCULAR RISK.”
	Dr. Dhruv  Madann	Dr. Raju B	“ROLE OF NOVEL BIOMARKER HEART TYPE FATTY ACID-BINDING PROTEIN (H-FABP) IN DIAGNOSIS ACUTE CORONARY SYNDROME IN EMERGENCY DEPARTMENT- A ONE YEAR CROSS SECTIONAL STUDY IN KLES DR. PRABHAKAR KORE HOSPITAL & MRC, BELGAUM.”
	Dr.Yashasvi Agarwal	Dr. Anjali R M	“CROSS SECTIONAL STUDY COMPARING IMMATURE PLATELET FRACTION WITH DEGREES OF HYPERGLYCEMIA IN TYPE 2 DIABETES MELLITUS IN POST CORONARY ANGIOGRAPHY PATIENTS AT KLES DR. PRABHAKAR KORE HOSPITAL”
	Dr. Adarsh Sinhal	Dr. Prakash Babaliche	“STUDY OF EFFECT OF SERUM POTASSIUM LEVELS ONPATIENTS WITH ORGANOPHOSPHATE POISONING PRESENTING TO KLES DR. PRABHAKAR KORE HOSPITAL & MRC, BELAGAVI- A 1 YEAR OBSERVATIONAL STUDY.”
	Dr. Nidhi  Mangal Wadhe	Dr. Arif Maldar	“RATIO OF PLATELET COUNT TO SPLENIC DIAMETER AS A PREDICTOR OF ESOPHAGEAL VARICES IN CIRRHOSIS OF LIVER: A CROSS SECTIONAL STUDY.”
	Dr. Dharoja Vijayakumar Ramnikbhai	Dr. Naveen Angadi	“STUDY OF SPECTRUM OF PRECIPITATING FACTORS OF HEPATIC ENCEPHALOPATHY IN CIRRHOSIS OF LIVER WHICH IS A CROSS SECTIONAL STUDY FOR 1 YEAR AT KLES DR PRABHAKAR CORE CHARITABLE HOSPITAL BELAGAVI.”
	Shubham Kapse	Dr.Arathi Darshan	“SCREENING FOR OBSTRUCTIVE SLEEP APNOEA IN PATIENTS WITH TYPE 2 DIABETES MELLITUS USING STOP BANG SCORING AND ITS CORRELATION WITH HSCRP LEVELS.”
	Dr. Arush Vedwa	Dr.Raju Badiger	“CORRELATION OF SERUM HDL WITH SOFA SCORE IN SEPSIS AND ITS PROGNOSTIC VALUE IN PATIENTS ADMITTED IN INTENSIVE CARE UNIT AT KLE DR. PRABHAKAR KORE HOSPITAL AND MEDICAL RESEARCH CENTRE, BELAGAVI- A PROSPECTIVE COHORT STUDY”
	Dr.Aswin Sasi Kumar C K	Dr. V. A. Kothiwale	“A ONE YEAR OBSERVATIONAL STUDY TO ASSESS THE KNOWLEDGE ATTITUDE AND PRACTICES ABOUT HYPOGLYCEMIA IN DIABETIC PATIENTS PRESENTING WITH HYPOGLYCEMIA IN A TERTIARY CARE CENTRE OF NORTH KARNATAKA (DR. PRABHAKAR KORE HOSPITAL AND M.R.C)”,
	Dr. Prathamesh  Powalkar	Dr. V. G. Somannavar	“STUDY OF IMMATURE GRANULOCYTE COUNT AS EARLY DIAGNOSTIC MARKER TO DIFFERENTIATE BETWEEN SIRS AND SEPSIS PATIENTS”,
	Dr. Jale Venkat	Dr. Anwar Mujawar	“THE USE OF SMART-COP SCORE IN PREDICTING SEVERITY OUTCOMES AMONG PATIENTS WITH COMMUNITY ACQUIRED PNEUMONIA ADMITTED AT TERITIARY CARE CENTER BELAGAVI- A CROSS SECTIONAL STUDY”,
	Dr. Parati Sejal Shivkumar	Dr. Madhav Prabhu	“TO STUDY THE CORRELATION OF URINE MELATONIN WITH METABOLIC SYNDROME AND ITS MANIFESTATION AT TERTIARY CARE HOSPITAL- A CROSS SECTIONAL STUDY”,
	Dr. Dondapati Venkata Harshit	Dr.Arif D. Maldar	“A STUDY OF LIPID PROFILE AMONG THE PRE-MENOPAUSAL AND POST- MENOPAUSAL WOMEN A CROSS SECTION STUDY IN A TERTIARY CARE CENTER”,
	Dr. Ghantasala Raghava	Dr. Arathi Darshan	“DIAGNOSTIC VALUE OF ALCOHOLIC LIVER DISEASE/ NON ALCOHOLIC FATTY LIVER DISEASE INDEX ( ANI ) IN DIFFERENTIATING ALCOHOLIC LIVER DISEASE AND NONALCOHOLIC FATTY LIVER DISEASE ONE YEAR BASED OBSERVATIONAL STUDY IN TERITARY CARE CENTRE”,
	Dr. Gadiraju Lakshmi Taralika	Dr. Jayaprakash Appajigol	“TO COMPARE CLINICAL PROFILE AND OUTCOMES OF ACINETOBACTER BAUMANNI CAUSING INFECTION VS COLONIZATION IN ICU PATIENTS”,
	Dr. Tatireddy Sai Sindhu	Dr. V. G. Somannavar	“A STUDY OF BLOOD UREA NITROGEN AND SERUM ALBUMIN RATIO IN PATIENTS OF PNEUMONIA AT A TERITARY CARE HOSPITAL, BELAGAVI”,
	Dr. Joshi Ameya Mukund	Dr. Rekha S Patil	“PLATELET INDICES IN PATIENTS OF TYPE II DIABETES MELLITUS AT TERTIARY CARE TEACHING HOSPITAL- ONE YEAR CROSS SECTIONA LSTUDY”,
	Dr. Swetha Sunkara	Dr. Rekha S Patil	“ASSOCIATION BETWEEN 24 HOUR URINARY SODIUM AND POTASSIUM EXCRETION AND BLOOD PRESSURE IN NEWLY DIAGNOSED HYPERTENSIVESUBJECTS, A ONE YEAR CROSS SECTIONAL STUDY AT A TERTIARY CARE HOSPITAL”,
	Dr. Emmunur Thogira Susrut	Dr. Arathi Darshan	“USE OF IMMATURE PLATELET FRACTION TO PREDICT TIME TO PLATELET RECOVERY IN PATIENTS WITH DENGUE INFECTION AND FOR OPTIMAL MANAGEMENT”,
	Dr. Bhavan Vedha Panguluri	Dr. Naveen Angadi	“ROLE OF PANC3 SCORE AND HSCRP IN PREDICTING SEVERITY OF ACUTE PANCREATITIS IN PATIENTS ADMITTED AT TERTIARY CARE CENTRE, BELAGAVI-A ONE YEAR CROSS SECTIONAL STUDY”,
	Dr. Kambli Yash Ichchant	Dr. Dnyanesh N. Morkar	“ROLE OF PLATELET INDICES AND THEIR KINETICS AS PREDICTOR OF MORALITY IN SEPSIS PATIENTS ADMITTED AT KLE DR. PRABHAKAR KORE HOSPITAL AND MEDICAL RESEARCH CENTER, BELAGAVI- A ONE YEAR OBSERVATIONAL STUDY”,
	Dr.Pavan Harithasa N	Dr. Raju H. Badiger	“STUDY OF THYROID HORMONE PROFILE IN PATIENTS WITH ACUTE CORONARY SYNDROME”,
	Dr. Aishwarya N Udupa	Dr. Arathi Darshan	“TO STUDY THE PROGNOSIS OF PATIENTS WITH INTRACEREBRAL BLEED USING ICH SCORE, ONE YEAR PROSPECTIVE OBSERVATIONAL STUDY AT TERTIARY CARE HOSPITAL, BELAGAVI”,
	Dr. Rishika R Reddy	Dr. Naveen Angadi	“A STUDY TO CORRELATE SERUM LACTATE ALBUMIN RATIO TO RAAS SCORING SYSTEM IN SEPSIS IN MICU”,
	Dr. Akhil Prasad Kumbar	Dr. Dnyanesh N. Morkar	“CORRELATION BETWEEN ATHEROGENIC INDEX OF PLASMA,TRIGLYCERIDE-GLUCOSE INDEX AND OUTCOME OF ACUTE ISCHEMIC STROKE IN PATIENTS ADMITTED AT KLE DR. PRABHAKAR KORE HOSPITAL AND MEDICAL RESEARCH CENTRE, BELAGAVI-A ONE YEAR LONGITUDINAL STUDY”,
	Dr. Athotta Sreeja	Dr. Anjali R. Metgudmath	“TO STUDY VOLUME, CONDUCTIVITY, SCATTER PARAMETERS OF NEUTROPHILS AS AN EARLY DIAGNOSTIC TOOL IN ACUTE BACTERIAL INFECTIONS AT A TERITIARY LEVEL CENTRE- A RETROSPECTIVE CASE
	Dr. Shivansh Yadav	Dr. Rekha S. Patil	PLASMA  FIBRINOGEN LEVEL IN ADULT  PATIENTS WITH TYPE 2 DIABETES  MELLITUS  AND ITS ASSOCIATION WITH MICROALBUMINURIA AND GLYCEMIC CONTROL AT TERTIARY CARE TEACHING HOSPITAL  ONE YEAR CROSS SECTIONAL STUDY.
	Dr. Aman Aggarwal	Dr. V. A. Kothiwale	Study of metabolic parameters in the medical students of Jawaharlal Nehru Medical College- A one year cross sectional study in KLE Dr. Prabhakar Kore Hospital and MRC Belagavi.
	Dr. Amaravai Varun Reddy	Dr. Raju H. Badiger	Role of High-Density lipoprotein cholestrol in cerebrovascular accident and comparion of high-denstiy lipoprotein level in ishcemic and hemmorrhagic stroke

COMPLETED DISSERTATION

	Dr. Ankur Batra	Dr. V.A.Kothiwale	Effects Of Blood Pressure Reduction On High Sensitivity C-Reactive Protein (Hscrp)
	Dr. Sandeep S Donagaon	Dr. A.J. Dhumale	Eosinopenia Is A Reliable Marker Of Sepsis On Admission To Medical Intensive Care Units
	Dr Sachin Bongale	Dr. V.G.Somannavar	Study Of  Serum Ferritin In Metabolic Syndrome
	Dr.Shet Sudhir Mangaldas	Dr.M.S. Khanpet	The Relationship Between Thyroid Function Test And Various Stages Of Renal Failure [Stages As Per Egfr]
	Dr. Bobby Varghese	Dr. Rekha S Patil	Relationship Of Neck Circumference To Cardiovascular Risk Factors
	Dr. Yogesh Garg	Dr. Naveen Angadi	Association Of Plasma Bnp & Hs- Crp Levels With Echocardiographic Derived Parameters Of Cardiac Function In Heart Failure Patients
	Dr. Amit Govind Kamat	Dr. B. Srinivas	Non Motor Symptoms In Parkinson’s Disease
	Dr. Yeshavanth G	Dr. Arathi Darshan	The Association Of Egft, Serum Lipids And Inflammatory Biomarkers With Normal Renal Function In Patients With Type 2 Diabetes Mellitus
	Dr. Pallav Goswami	Dr. Prakash Babaliche	Clinical Profile Of Acute Viral Gastroenteritis- A One Year Cross Sectional Study
	Dr. Manika Mahajan	Dr. V. A. Kothiwale	Clinical And Laboratory Profile Of Prehypertension In Adults- A One Year Cross Sectional Study.
	Dr. Smita Suresh Advani	Dr. Rekha S. Patil	Clinical Haematological And Cytogenetic Profile In Myelodysplastic Syndrome- A One Year Cross Sectional Study.
	Dr. Vishwanath Hesarur	Dr. B. Srinivas	Clinical  And Laboratory Profile Of Pulmonary Tuberculosis Among Hiv Seropositive Patients- A Cross Sectional Study.
	Dr. Sriharsha A. S.	Dr. Prakash K. Phadnis	A Cross Sectional Study To Know The Prevalence Of Insulin Resistance Among Non Obese Hypertensives Attending Kles Dr. Prabhakar Kore Hospital And Mrc, Belgaum.
	Dr. Nikhil Sunkarineni	Dr. Neeta Deshpande	Correlation Of Blood Inflammatory Markers To Ankle Brachial Index In Asymptomatic Atherosclerosis In Type 2 Diabetes Mellitus Patients- A Cross Sectional Study.
	Dr. Anand Kumar M.	Dr. Mallikarjun S. Khanpet	A Cross Sectional Study To Know The Profile Of Patients With Acute Interstitial Nephropathy Attending Kles Dr. Prabhakar Kore Hospital And Mrc, Belgaum.
	Dr. Dhaval Malde	Dr. A. J. Dhumale	Clinical Profile Of Patients With Brain Stem Stroke Admitted To Kles Dr. Prabhakar Kore Hospital & Mrc, Belgaum.
	Dr. Badam Manoj Kumar	Dr. Arathi Darshan	A Cross Sectional Study To Find The Association Between Prolonged Qtc Interval And Microalbuminuria In Patients Of Type 2 Diabetes Mellitus.
	Dr. Ranjan Modi	Dr. V. A. Kothiwale	Assessment Of Apolipoproteins In Patients Of Coronary Artery Diseases.
	Dr. Toby Chandy	Dr. Rekha S. Patil	Prevelance Of Anti Ccp Antibodies In Patients With Rheumathoid Arthritis- One Year Cross Sectional Study At Kles Dr. Prabhakar Kore Hospital & Mrc, Belgaum.
	Dr. Sneha Sirdeshpande	Dr. B. Srinivas	Association Of Correlation Of Serum Cholesterol, Hdl-C, Ldl-C Levels With Degree Of Radiological Extent And Degree Of Sputum Positivity In Pulmonary Tuberculosis- A One Year Cross Sectional Study.
	Dr. Chandramouli Reddy	Dr. Prakash K. Phadnis	To Study The Clinical Profile, Etiology And Outcome Of Ventilator Associated Pneumonia. A One Year Cross Sectional Study.
	Dr. Hemanth Kumar S. R.	Dr. M. S. Khanpet	Prevalence Of Asymptomatic Urinary Abnormalities Among Kle University Students- A One Year Cross Sectional Study.
	Dr. Veena P. Munavalli	Dr. A. J. Dhumale	Serum Cystatin C Concentration Levels As A Marker Of Acute Renal Failure In Critically Ill Patients.
	Dr. Harshavardhan Rao	Dr. Arathi Darshan	A Clinical Study To Determine The Association Of Interleukin-18 With Metabolic Syndrome.
	Dr. Pakalpati Sasanka	Dr. Prakash Babaliche	Silent Brain Infarcts In Patients With Non-Specific Neurological Symptoms – A One Year Cross Sectional Study, At Kles Dr. Prabhakar Kore Hospital And M. R. C. Belgaum.
	Dr. Ankur Batra	Dr. V. A. Kothiwale	Effects Of Blood Pressure Reduction On High Sensitivity C-Reactive Protein (Hscrp)
	Dr. Sandeep S Donagaon	Dr. A.J. Dhumale	Eosinopenia Is A Reliable Marker Of Sepsis On Admission To Medical Intensive Care Units
	Dr. Sachin Bongale	Dr. V.G.Somannavar	Study Of  Serum Ferritin In Metabolic Syndrome
	Dr. Shet Sudhir Mangaldas	Dr.M.S. Khanpet	The Relationship Between Thyroid Function Test And Various Stages Of Renal Failure [Stages As Per Egfr]
	Dr. Bobby Varghese	Dr. Rekha S Patil	Relationship Of Neck Circumference To Cardiovascular Risk Factors
	Dr. Yogesh Garg	Dr. Naveen Angadi	Association Of Plasma Bnp & Hs- Crp Levels With Echocardiographic Derived Parameters Of Cardiac Function In Heart Failure Patients
	Dr. Amit Govind Kamat	Dr. B. Srinivas	Non Motor Symptoms In Parkinson’s Disease
	Dr. Yeshavanth G.	Dr. Arathi Darshan	The Association Of Egft, Serum Lipids And Inflammatory Biomarkers With Normal Renal Function In Patients With Type 2 Diabetes Mellitus
	Dr. Pallav Goswami	Dr. Prakash Babaliche	Clinical Profile Of Acute Viral Gastroenteritis – A One Year Cross Sectional Study
	Dr. Doshi Darshan Kiran	Dr. Prakash Babaliche	Role Of Ns1 Antigen Detection In Early Diagnosis Of Dengue Virus Infection – A One Year Hospital Based Cross-Sectional Study
	Dr. Nitish Kumar Mahajan	Dr. B. Srinivas	Correlation Of Serum Magnesium Levels In The Clinical Outcome Of Critically Ill Patients – A One Year Prospective Cohort Study.
	Dr. Amit Goel	Dr. A.J.Dhumale	Study Of Metabolic Syndrome In Hiv Positive Patients In A Tertiary Hospital
	Dr. Thacker Vinit       Arvindbhai	Dr. M.S.Khanpet	Correlation Between Serum Adiponectin Levels And Chronic Kidney Disease Stage 2 To Stage 4 In Patients With Type 2 Diabetes Mellitus – A One Year Cross Sectional Study
	Dr. Gaurav S.  Subhedar	Dr. Arati Darshan	A One Year Cross Sectional Study: To Study The Association Of Serum Gamma Glutamyl Transferase Levels With Metabolic Syndrome- Dr. Prabhakar Kore’s Kles Hospital, Belgaum.
	Dr. Salil V. Patkar	Dr. P.K.Phadnis	Correlation Of Serum Uric Acid Levels & Lipid Levels In Patients With Ischaemic Cerebrovascular Accident – A One Year Cross Sectional Study
	Dr. Amit K. Sarda	Dr. Naveen Angadi	To Study Correlation Of Serum Vitamin D Levels In Patients With Pulmonary Tuberculosis – A One Year Hospital Based Cross Sectional Study.
	Dr. Anshul Goyal	Dr. V.G. Somannavar	Estimation Of Levels Of Vitamin D In Type 2 Diabetes Mellitus – One Year Cross Sectional Study
	Dr. Naveen Charantimath	Dr. Rekha Patil	Estimation Of Csf Cortisol Levels In Patients With Meningitis – A One Year Cross-Sectional Study
	Dr. Kulkarni Aditya Vivekanand	Dr. Santosh Hajare	Estimation Of Aminotranferases Levels In Normal Individuals In Relation To Body Mass Index – A Cross Sectional Study
	Dr. Varun Kumar B.	Dr. V. A. Kothiwale	Estimation Of Serum Procalcitonin Levels In Patients With Systemic Inflammatory Response Syndrome And Sepsis – A One Year Cross-Sectional Study
	Dr. Ravi Pangi	Dr. V.A.Kothiwale	To Study The Clinical Profile Of Atrial Fibrillation In Elderly Patients A One Year Cross Sectional Study At Kles Dr. Prabhakar Kore Hospital & Mrc Belgaum.
	Dr. Kabir Sethi	Dr. A.J. Dhumale	“ Role Of Novel Biomarker Heart Type Fatty Acid Binding Protein In Diagnosing Acute Coronary Syndrome In Comparison With  Troponin T  And Ck-Mb A One Year Cross Sectional Study In Kles Dr. Prabhakar Kore Hospital & Mrc, Belgaum.
	Dr. Rajan Mittal	Dr. V.G.Somannavar	“Study Of Cardiac Manifestations In  Patients Of Hiv Infection”  A One Year Cross Sectional Study At Kle University, Belgaum.
	Dr. Gadve Shriya Suresh	Dr.M.S.Khanpet	A One Year Longitudinal Study Of The Outcome Of Papillary Necrosis Causing Acute Renal Failure In Patients Presenting To Kles Dr. Prabhakar Kore Hospital And Medical Research Centre, Belgaum.
	Dr. Mohit Arora	Dr. Rekha S Patil	To Study The Incidence Of Cardiac Manifestations In Dengue Fever In Patients Admitted In Kles Dr. Prabhakar Kore Hospital Based Descriptive Study
	Dr. Ganavi.V.P.	Dr. Naveen Angadi	“Prevalence Of Primary Hypothyroidism In Metabolic Syndrome” A One Year Cross Sectional Study At Dr. Prabhakar Kore Hospital And Medical Research Centre, Belgaum.
	Dr. Nishant Dubey	Dr. B. Srinivas	A Clinical Profile Of Acute Myocardial Infarction With  Atypical Presentation-  A One Year Hospital Based Descriptive Study
	Dr. Sharanabasveshwar R.P.	Dr. Santosh Hajare	Etiological Profile Of Patients Presenting With Upper Gastro Intestinal Bleeding- A One Year Cross Sectional Study
	Dr. Bhise Shekhar Ramachandra	Dr. Arathi Darshan	“ Correlation Of Inter Arm Systolic Blood Pressure Difference To Ankle Brachial Index [ Abi ] In Detecting Peripheral Vascular Disease In Type Two Diabetes Mellitus Patients – One Year Cross Sectional Study In Kles Dr. Prabhakar Kore Hospital & Mrc, Belgaum.
	Dr. Pradeep Gubba	Dr. Prakash Babaliche	“ Variation In Common Lipid Parameters In Malaria Infected Patients- A One Year Cross Sectional Study In Kles Dr. Prabhakar Kore Hospital & Mrc Belgaum”
	Dr. Akshay Konnur	Dr. Anjali Metgudmath	“To Study The Clinical And Biochemical Profile Of Liver Involvement In Dengue Infected Patients A One Year Cross Sectional Study In Kles Dr. Prabhakar Kore Hospital & Mrc Belgaum.
	Dr. Sameer Mehta	Dr. V. A. Kothiwale	The value of shock index in prognosticating mortality in patients with severe sepsis and septic shock.
	Dr. Rohit Morlawar	Dr. V. A. Kothiwale	Comparative Analysis Trend of Primary and Secondary Dengue Infection – A one year Hospital based study.
	Dr. Kulkarni Nachiikait Shirish	Dr. Santosh Hajare	Estimation of senior estradiol levels and its co-relation with BISAP score in severe Acute Pancreatitis – One year hospital based cross sectional study.
	Dr. Rocky Katheria	Dr. Vijay G. Somannavar	Clinical study of acute myocardial infarction in relation with sr. uric acid level.
	Dr. Viraj Vasudev Yerramalla	Dr. Vijay G. Somannavar	Clinical study of organophosphorus compound poisoning and comparison of serum pseudo cholinesterase levels with its complications / outcome.
	Dr. Vamshi A.	Dr. Rekha S. Patil	Microalbuminuria: Biomarker of sepsis and prognostic significance in critically ill patients.
	Dr. Soumya Poduval Phagum	Dr. Rekha S. Patil	Study of prognostic significance of serum levels of creative kinase in OPP. Importance of elevated serum amylase in patients of organophosphorous compound poisoning.
	Dr. Ch. Prudhvi Krishna	Dr. B. Srinivas	Clinical and laboratory study of arrhythmias in acute myocardial infarction and its prognostic significance. Study of arrhythmias in AMI and its correlations with electrolyte imbalance.
	Dr. Suhas M.	Dr. B. Srinivas	To study the relationship between carotid intima-media thickness & disease activity in rheumatoid arthritis.
	Dr. Naman Mukhi	Dr. Aarthi Darshan	To identify risk of type 2 diabetes mellitus using Indian diabetes risk score in medical students.
	Dr. Priyanka A. Patil	Dr. Aarthi Darshan	Relationship between Mean Platelet volume & severity of acute Ischemic Brain shock in type 2 diabetes mellitus.
	Dr. Siddharth Madnani	Dr. Prakash Babaliche	Clinical profile of hyponatremia in adult patients admitted to KLES Dr. Prabhakar Kore hospital & MRC, Belgaum
	Dr. Sajal Kamat	Dr. Dnyanesh N. Morkar	Nutritional Assessment of HIV patients admitted to tertiary care hospital using the phase angle Z score.
	Dr. Ashwin S. P.	Dr. M. S. Khanpet	Asymptomatic renal artery diseases in ischemic heart disease patients undergoing coronary angiography in KLES Dr. Prabhakar Kore Hospital and MRC, Belgaum.
	Dr. Arjun Hosalli	Dr. Anjali R. Metgudmath	To study mean platelet volume in patients of acute coronary syndromes.
	Dr. Saurabh Gaur	Dr. V. A. Kothiwale	Correlation of thyroid hormoneprofile with apache ii score as a prognostic marker in patients with sepsis in intensive care unit- a one year cross sectional study at kle dr. Prabhakar kore hospital, Belgaum
	Dr. U. M. Vaishak	Dr. Anjali Metgudmath	The correlation between serum homcysteine levels and hypothyroidism – a one year case control study in kles hospital belgaum
	Dr. Rahul Bhume	Dr. Prakash Babaliche	Clinical profile and role of rapid serological tests(typhifast igm and enterocheck igg/igm) for diagnosis of typhoid fever – a one year cross sectional study in kles dr. Prabhakar kore hospital & mrc, belgaum
	Dr. Samarth	Dr. Dnyanesh Morkar	Estimation of serum testosterone level and its co-relation with hematocrit in type 2 diabetes male patients – one year hospital based prospective case –control study in kles dr. Prabhakar kore charitable hospital & mrc, belgaum
	Dr. ChetanaKhavatkopp	Dr. M. S. Khanpet	Study of outcome of arteriovenous fistula by prior assessment of vascular dimensions – a preospective one year study in kles dr. Prabhakar kore charitable hospital, belgaum
	Dr. RavikanthRamadhenu	Dr. V. A. Kothiwale	Estimation of subcutaneous fat thickness using various anthropometric measures and their correlation in type 2 diabetes mellitus – a one year cross sectional study
	Dr. P Krishna Prasad	Dr. Rekha S Patil	Precipitating factors for hepatic encephalopathy in cirrhosis of liver – a one year hospital based cross sectional study
	Dr. Samrat Ashok. Shah	Dr. B. Srinivas	Musculoskeleteal manifestations of diabetes mellites – a one year cross sectional study at kles dr. Prabhkar kore hospital
	Dr. Rikita R. Mudhol	Dr. Srinivas B	Prevalance of thyroid disorders in type 2 diabetic patients – a one year cross sectional study
	Dr. MandarGopalkrishnaWaghralkar	Dr. Vijay Somannavar	Correlation of platelet count/splenic diameter ration for the diagnosis of esophageal va-rices in patients of cirrhosis of liver
	Dr. Vaibhavi G Velangi	Dr. Rajeev Malipatil	Estimation of csf lactate as diagnosis marker to differentiate pyogenic meningitis from non-pyogenic meningitis
	Dr. RavindraKantamaneni	Dr. Santosh Hajare	Etiological profile of patients presenting with lower gastrointestinal bleeding – a one year cross sectional study
	Dr. Venkat Reddy Palvai	Dr. Rekha S Patil	Estimation of the lipoprotein (a) in acute ischemic stroke
	Dr. Shivakumar V. Turamari	Dr. Vijay Somannavar	Autonomic dysfunction in cirrhosis of liver, a one year cross sectional study at kles dr. Prabhakar kore hospital and mrc, belgaum
	Dr. Yogesh om Sharma	Dr. Arathi Darshan	Study of minimal hepatic encephalopathy in patients with cirrhosis of liver
	Dr. Deebanshu Gupta	Dr. V. A. Kothiwale	“Study of erectile dysfunction in T2DM”.
	Dr. Ashray S. Kole	Dr. V. A. Kothiwale	’ Iron studies and its correlation with BNF Levels in Heart failure’
	Dr. Ratna M. Bhustali	Dr. V. G. Somannavar	‘Waist to height ratio as a screening tool in the assessment of cardiometabolic risk factors in comparison with waist circumference wast to
	Dr. Anish John Kuriakose	Dr. V. G. Somannavar	‘Validity of bedside clinical scoring systems in classifying stroke and its subsequent management.’
	Dr. Aakansha Pritam Sinha	Dr. Rekha S. Patil	‘Sequential organ failure assessment score (SOFA) as a prognostic marker in patients with sepsis in a tertiary care ICU’.
	Dr. Pooja Motimath	Dr. Rekha S. Patil	‘Serum testosterone in Hypertensive patients – A cross sectional study.
	Dr. Kumar Siddharth	Dr. Anjali Metgudmath	‘Cross Sectional study of HsCRP  with  statin to be exceeded.
	Dr. Harshbir Singh Puar	Dr. B. Srinivas	‘ Clinical lab evaluation of acute kidney injury in geriatric population’.
	Dr. Mohnish G. Patel	Dr. B. Srinivas	‘ Clinical profile of toxic snake bite cases in patients admitted in tertially cow Hospital’.
	Dr. Abhishek T. G.	Dr. Arathi Darshan	‘To study the association of carotid intimal medial thickness in metabolic syndrome’.
	Dr. Vijayalakshmi Chikkamath	Dr. Rajeev Malipatil	‘A study of plasma fibrinogen levels in T2DM and its relation to glycemic control’.
	Dr. Ankita Menon	Dr. Prakash Babaliche	‘A study of left ventricular function by echocardiography in HIV infected patients’.
	Dr. Paladugu Sai Nivead	Dr. Santosh Hazare	‘Clinical profile of non-alcoholic strators syndrome’.
	Dr. Shaik Hussain Basha	Dr. M. S. Khanpet	‘Clinical and microbiological features of UTI’.
	Dr. Joel George	Dr. Dnyanesh Morkar	‘ECG findings in opposite with special reference to QTC’.
	Dr. Ankita Aneja	Dr. V.A. Kothiwale	To study clinical profile of different  serotypes of Dengue
	Dr. Chougule Nikhil Ashok	Dr. V.A. Kothiwale	Multifactorial influences on lipid profile in dyslipidemia patient
	Dr. Krishna C.S.	Dr. Rajeev Malipatil	Comparison of capillary blood glucose versus arterial  blood glucose in patients on vasopressor support
	Dr. Rishi Raman	Dr. V.G. Somannavar	A Clinical profile and etiological study of pleural effusion 4 days longitudinal study
	Dr. Aamna Maniyar	Dr. V.G. Somannavar	One year cross sectional study of predicting  the need for ventilator  support in patients with organophosphorus  compound poisoning
	Dr. Pooja P Lokkur	Dr. Rekha S Patil	Apo A1 and Lipid profile in Cirrhotic patient  and its correlation with prognostic scores – a one year cross sectional study at KLE’s Dr. Prabhakar Kore Hospital & MRC Belagavi.
	Dr. Abhilash B  Mareguddi	Dr. Rekha S Patil	Red cell distribution width and neurological scoring systems in Acute stroke patient
	Dr. Vivek V Shirol	Dr. B. Srinivas	Prevalence of gall bladder stones in T2DM patient and As associated risk factors – A cross sectional study.
	Dr. Vinay A Issac	Dr. B. Srinivas“	The relationship between glycosylated Hemoglobin and mean platelet volume in T2 DM Patients.
	Dr. Dandamudi K Dheeraj	Dr. Arathi Darshan	Observational study of association of son1-radiographically assessed visceral and subcutaneous abdominal fat with insulin  resistance in patient with prediabetes
	Dr. Chauhan D Piraji	Dr. Arathi Darshan	To Study serum calcium in Dengue Fever
	Dr. Chafekar Nahush Deodatta	Dr. Prakash Babaliche	Study of association of Vit  B12 deficiency  and clinical neuropathy with metformin use in T2 DM Patients.
	Dr. Harish V Ballur	Dr. Naveen Angadi.	Study of clinical profile of non-Alcoholic  fatty liver  disease  [NAFLD] and its association with Metabolic syndrome
	Dr. Natasha P Madkaikar	Dr. Anjali R Metgudmath	A one year prospective study of thyroid dysfunction geriatric population & its clinical correlation .
	Dr. Srikanth Yadav Meesala	Dr. Dnayesh Morkar	To study renal manifestations in dengue fever.
	Dr. Aditi Rao	Dr.V A Kothiwale	A comparison of clinical profiles of normal and abnormal coronary arteries : a case control study
	Dr. Ramneek Mittal	Dr.V A Kothiwale	Clinical profile of left bundle branch block in tertiary care hospital – a cross sectional stud
	Dr. Vijayalaxmi	Dr. Pournima Patil	Study of factors affecting the patients global visual analogue scale in patients of rheumatoid arthritis – a one year hospital based cross sectional study in kle’s dr. Prabhakar  Kore hospital, Belagavi
	Dr. Silpasri Uthaman	Dr. B Srinivas	Stud of neutrophils : lymphocyte ratio as a novel marker of diabetic nephropathy in type 2 diabetes mellitus – one ear hospital based cross sectional study
	Dr. Rani Jawahar Ghali	Dr. B Srinivas	Evaluation of serum uric acid level in primary hypertension – a one year cross sectional study
	Dr. Mohammed Muffasil	Dr. Aarati Darshan	Study of partial thromboplastin time and prothrombin time as predictors of bleeding in dengue fever – one ear of cross sectional study
	Dr. Lakshmi Krishnan	Dr. Aarathi Darshan	Correlation of serum prolactin level to child –pugh scoring system in cirrhosis of liver – a one year cross sectional study
	Dr. Soumya N S	Dr. Rekha Patil	Prevalence of secondary hyperparathyroidism in patients with stage 5 chronic kidney disease on maintenance hemodialysis – a one ear hospital based cross sectional study
	Dr. Patil Vivek Malagouda	Dr. Rekha S Patil	Serum calcium level as a prognostic marker in acute pancreatitis – one year hospital based cross sectional study
	Dr. M Bharat Reddy	Dr. Naveen Angadi	Measurement of serum cholinesterase levels in type 2 diabetes and its possible role as a marker for cardiovascular risk assessment – one ear hospital based cross sectional stud in KLE;s dr. Prabhakar kore’s charitable hospital
	Dr. Akshay Jain	Dr. V G Somannavar	Estimation of blood urea nitrogen/ creatinine ratio and urine specific gravity to assess dehydration as a predictor of outcome in acute ischemic stroke patients – one year hospital based cross sectional study
	Dr. Omkar S Rudra	Dr. V G Somannavar	The effect of the severity of anaemia on hba1c in non diabetic patients – a one year hospital based study in kle’s Prabhakar kore hospital and medical research centre
	Dr. Soumya Parne	Dr. Anjali Metgudmath	Serum bilirubin as a severity and prognostic indicator in acute ischemic stroke – a tertiary hospital based one year observational study in Belagavi
	Dr. Ravi N. Sangapur	Dr. Prakash Babaliche	Serum magnesium level and its correlation with primary hypertension – one year cross sectional study
	Dr. Madduri Pavan Kumar	Dr. Dnyanesh Morkar	Clinical profile of fever in the geriatric patients admitted in ICU – a one Year hospital based cross sectional stud
	Dr. Kopal Gupta	Dr. V.A. Kothiwale	“Association Between Elevated Serum Uric Acid Levels And Islet Beta Cell Function Indices In Newly Diagnosed Type 2 Diabetes Mellitus – A One Year Cross Sectional Study At Kle’s Dr Prabhakar Kore Hospital And Medical Research Centre ”,
	Dr. Shreyas U Akki.	Dr. V.A. Kothiwale	“Role Of Troponin In Identifying Left Ventricular Ejection Fraction Of <=40% In Acute St Elevated Myocardial Infarction: A One Year Cross Sectional Study In Kle Dr Prabhakar Kore Hospital And Mrc Belagavi”,
	Dr. Sharath Tukade	Dr. Pournima S Patil	“The Pattern Of Prior Drug Usage, Level Of Disease Activity At Presentation To Rheumatology Clinic In Rural Patient Of Rheumatoid Arthritis – One Year Observational Study From Rheumatology Clinic At Kles Dr. Prabhakar Kore Hospital And Mrc, Belagavi”,
	Dr. Tirupati V Sai Vaibhav	Dr. V.G. Somannavar	“Correlation Of Serum Lipid Profile In Patient With Anemia – A One Year Cross Sectional Study In Kle’s Dr. Prabhakar Kore Hospital & Mrc”,
	Dr. Vikram J Khardenavis	Dr. V.G. Somannavar	“Comparison Of Red Blood Cell Morphology And Indices In Patients Of Vegetarian And Non Vegetarian Diet, A One Year Cross Sectional Study In Kles Dr. Prabhakar Kore Hospital And Mrc”
	Dr. Rajani Durannavar	Dr. Rekha S Patil	“To Study The Serum Lactate Albumin Ratio In The Patients With Sepsis A One Year Cross Sectional Study In Kles Dr. Prabhakar Kore Hospital And Mrc, Belgavi”
	Dr. Rishabh Agarwal.	Dr. Rekha S Patil	“Incidence And Risk Factors Associated With Development Of Post Infectious Irritable Bowel Syndrome (Ibs): A One Year Prospective Longitudinal Study At Kles Dr. Prabhakar Kore Hospital And Mrc, Belgaum”
	Dr. Sreedhar J Cherulil	Dr. Arif D Maldar	“Clinical And Electrocardiographic Profile Of Inferior Wall Myocardial Infraction, With Right Ventricular Involvement – A One Year Cross Sectional Study At Kle’s Dr Prabhakar Kore Hospital And Medical Research Centre”
	Dr. N Abhiram	Dr. Naveen Angadi.	“Clinical And Laboratory Profile Of Diabetes Hypertension Kidney Disease Syndrome – Dhkd Syndrome – A One Year Cross Sectional Study At Kles Dr Prabhakar Kore Hospital And Mrc”
	Dr. P Haritha	Dr. Arathi Darshan	“Prognostic Value Of Decaf Score In Patients With Acute Exacerbation Of Copd – A One Year Cross Sectional Study In Kle’s Dr. Prabhakar Kore Hospital And Medical Research Centre, Belagavi”
	Dr. Sneha V Karekar	Dr. Arathi Darshan	“Correlation Between Apri Index, Meld Score And Child Pugh Score In Cirrhosis Of Liver – A One Year Cross Sectional Study In Kle’s Prabhakar Kore Hospital And Medical Research Centre, Belagavi”
	Dr. Akash C	Dr. Raju Badiger	“Prognostic Role Of Neutrophil –Lymphocyte Ratio In Patients With Acute Ischaemic Stroke – One Year Cross- Sectional Study”
	Dr. Veera Vaishnavi Dulipalla	Dr. Madhav Prabhu	“Study Of Association Between Type 2 Diabetes Mellitus And Telomere Length A One Year Cross Sectional Study”
	Dr. Vattikonda Chandra Lekha	Dr. Jayaprakash Appajigol	“Study Of Risk Factors And Clinical Profile Of Patients With Acinetobacter Baumannii Infection Admitted In Medical Intensive Care Unit Of Tertiary Care Hospital, Belagavi. A One Year Observational Study”
	Dr. Santosh Kumar	Dr. D. Morkar	“To Study Clinical Factors And Serum Testosterone In Relation To Erectile Dysfunction In Hiv Infected Men At Kle’s Dr. Prabhakar Kore Hospital & Mrc, Belagavi – A One Year Observational Cross Sectional Study”
	Dr. Indu Yadav	Dr. Raju Badiger	Study Of Sick Euthyroid Syndrome In Organophosphate Poisoning –A Hospital Based One Year Cross Sectional Study In Kles’ Dr Prabhakar Kore Hospital And Medical Research Centre, Belagavi
	Dr. Vojjala Nishanth	Dr. Rekha S Patil	A Study Of Serum Ferritin Levels In Dengue Patients – One Year Hospital Based Cross Sectional Study
	Dr. Prashanth B M	Dr. Rekha S Patil	Study Of Correlation Between Serum Uric Acid And Hba1c In Prediabetic And Diabetics – A One Year Prospective Analytical Study
	Dr. Pavan Kumar B C	Dr. V G Somannavar	A Study On The Role Of Serum Calcium, Serum Albumin And Serum Uric Acid As Markers Of Initial Neurological  Severity And Short Term Outcome Indicators In Acute Ischemic Stroke
	Dr. Kabara Abhishek Laxmikant	Dr. Pournima Patil	Safety Profile Of Methotrexate In Patients With Rheumatoid Arthritis
	Dr. Sreekanth Chowdary	Dr. Arif  Maldar	Hyperuricemia As An Early Marker In Predicting The Mortality And Morbidity In Patients With Sepsis
	Dr. Vinay Arora	Dr. Arathi Darshan	Blood Pressure Monitoring In Normotensive Type – 2 Diabetics Using 24hr Blood Pressure Monitoring Device And Its Relationship With Anthropometric Measurements: A One Year Hospital Based Cross Sectional Study
	Dr. Aashna Pankaj Gandhi	Dr. Arathi Darshan	Eosinopenia As A Diagnostic Marker For Enteric Fever: A One Year Hospital Based Cross Sectional Study
	Dr. Manisha Dwivedi	Dr. Dnyanesh Morkar	Comparative Study Of Sofa, Apache Ii, Saps Ii, As A Predictor Of Mortality In Patients Of Sepsis Admitted In Medical Icu Of Kles Prabhakar Kore Hospital
	Dr. Pooja Yamini Devi Koruprolu	Dr. V A Kothiwale	Clinical Study Of Bacterial Profile And Antibiotic Sensitivity Pattern Of Isolates In Medical ICU
	Dr. Gayatri Sharma	Dr. Naveen Angadi	Assessment Of Anemia In Patients Of Primary Hypothyroidism
	Dr. K Goutham Sai Krishna	Dr.Madhav Prabhu	Study Of Association Of Leptin And Leucocyte Telomere Length With Body Mass Index In Adult Indian Population A One Year Cross Sectional Study
	Dr. Rishabh Soni	Dr. Jayaprakash Appajigol	Clinical Profile And Patterns Of Antimicrobial Resistance In Ventilator Associated Pneumonia Patients –A Cross Sectional Study
	Dr. Aishwarya Anil Patted	Dr. V A Kothiwale	Association Of Lipoprotein (A) In Coronary Artery Disease In Young Individuals
	Dr. Mohamed Faizan Thouseef	Dr. V G Somannavar	A Clinical Profile Of Urinary Tract Infection In Type 2 Diabetes Mellitus With Bacterial Culture And Antibiotic Sensitivity Patterns
	DR. SATHE VANDITA SUNIL	DR. V.A. KOTHIWALE	“STUDY OF COAGULATION PROFILE DYNAMICS IN PATIENTS WITH COVID 19 INFECTION – A ONE YEAR CROSS SECTIONAL STUDY IN KLE’S DR. PRABHAKAR KORE HOSPITAL AND MEDICAL RESEARCH CENTRE, BELAGAVI”.
	DR. MAHAVEER GUNDUMALA	DR. V.A. KOTHIWALE	“STUDY OF CLINICAL PROFILE AND ITS CORRELATION WITH PLATELET INDICES IN PATIENTS INFECTED WITH SARS-COV2 : A ONE YEAR CROSS SECTIONAL STUDY DONE IN KLES DR. PRABHAKAR KORE HOSPITAL AND MEDICAL RESEARCH CENTRE. BELAGAVI.
	DR. AMIT YOSHAAN JOSHI	DR. ANJALI R METGUDMATH	“STUDY OF CLINICAL PROFILE AND ITS CORRELATION WITH PLATELET INDICES IN PATIENTS INFECTED WITH SARS-COV2 : A ONE YEAR CROSS SECTIONAL STUDY DONE IN KLES DR. PRABHAKAR KORE HOSPITAL AND MEDICAL RESEARCH CENTRE. BELAGAVI.
	DR. AJMERA YOGESH A	DR.V.G. SOMANNAVAR	A STUDY OF CORRELATION BETWEEN NEUTROPHIL TO LYMPHOCYTE RATION AND PLATELET TO LYMPHOCYTE RATION IN PATIENTS OF CHRONIC KIDNEY DISEASE AT KLE’S DR. PRABHAKAR KORE HOSPITAL AND MRC, BELAGAVI
	DR. RAINA N DESHLAHRA	DR.V.G. SOMANNAVAR	“CORRELATION BETWEEN SERUM MAGNESIUM AND SEVERITY OF SEPSIS IN PATIENTS ADMITTED IN INTENSIVE CARE UNIT AT KLE DR. PRABHAKAR KORE HOSPITAL AND MEDICAL RESEARCH CENTRE, BELAGAVI- A CROSS SECTIONAL BASED STUDY”
	DR. DENNAS DAVIS E	DR. ANWAR MUJAWAR.	“A STUDY TO CORRELATION CLINICAL SEVERITY WITH HRCT THORAX FINDINGS IN COVID- 19 PATIENTS – ONE YEAR CROSS SECTIONAL STUDY AT KLES DR. PRABHAKAR KORE HOSPITAL & MRC ”
	DR. NIXON GOYAL	DR. REKHA S PATIL	“PRE-AND POST-HEMODIALYSIS COAGULATION PROFILE IN CHRONIC KIDNEY DISEASES PATIENTS – A ONE YEAR CROSS SECTIONAL STUDY AT TERTIARY CARE CENTRE”,
	DR. SHIVANI C BHAGWAT	DR. REKHA S PATIL	“THE EVALUATION OF EPICARDIAL FAT THICKNESS AND PLASMA FREE FATTY ACID LEVEL IN ACUTE ISCHEMIC STROKE – A ONE YEAR CROSS SECTIONAL STUDY AT KLES DR. PRABHAKAR KORE HOSPITAL AND MRC”
	DR.DASI VENKATA S REDDY	DR. MADHAV PRABHU	“STUDY OF CORRELATION BETWEEN LABORATORY BLOOD BIOMARKERS AT THE TIME OF ADMISSION WITH FINAL CLINICAL OUTCOME IN COVID 19 PATIENTS AT KLE DR PRABHAKAR KORE HOSPITAL” – A ONE YEAR HOSPITAL BASED CROSS- SECTIONAL STUDY,
	DR. AKASH KUMAR P	DR. ARATHI DARSHAN	“TO STUDY THE CLINICAL PROFILE, INFLAMMATORY BIOMARKERS AND CLINICAL OUTCOMES IN PATIENTS OF COVID-19 WITH TYPE 2 DIABETES MELLITUS : A ONE YEAR CROSS-SECTIONAL STUDY AT A TERTIARY CARE HOSPITAL ”
	DR. PRATIBHA GUPTA	DR. ARATHI DARSHAN	“A STUDY OF CARDIAC DYSFUNCTION IN CIRRHOSIS OF LIVER USING ECG, 2D-ECHO AND NT-PROBNP AND ITS CORRELATION WITH CHILD PUGH SCORE” – A ONE YEAR CROSS –SECTIONAL STUDY AT A TERTIARY CARE HOSPITAL,
	DR. NIDHI V YASHAVANTH	DR. ARATHI DARSHAN	“TO STUDY THE ASSOCIATION BETWEEN GLYCEMIC GAP AND ADVERSE OUTCOMES IN DIABETIC PATIENTS ADMITTED TO ICU-A ONE YEAR LONGITUDINAL STUDY IN KLE’S DR. PRABHAKAR KORE HOSPITAL AND MEDICAL RESEARCH CENTRE, BELAGAVI”,
	DR. ASHISH MOLLETI	DR. ARIF D MALDAR	“TO STUDY HNC-LL AS A POTENTIAL SCORE FOR PREDICTING SEVERITY IN COVID-19 PATIENTS – A ONE YEAR CROSS SECTIONAL STUDY AT A TERTIARY CARE HOSPITAL”
	DR. AKASH RAMASWAMY	DR. NAVEEN ANGADI	“CORRELATION BETWEEN THE CLINICAL & BIOCHEMICAL PROFILE SARS-COV-2 INFECTIONS WITH VARIOUS ABO BLOOD GROUPS-A ONE YEAR CROSS-SECTIONAL STUDY AT KLES DR. PRABHAKAR KORE HOSPITAL AND MRC”
	DR. LAKKIREDDY S REDDY	DR. NAVEEN ANGADI	A STUDY OF THYROID PROFILE AS A PREDICTOR OF MORTALITY AND MORBIDITY IN ICU ADMITTED PATIENTS – A ONE YEAR CROSS SECTIONAL STUDY IN KLE’S DR. PRABHAKAR KORE HOSPITAL & MRC”,
	DR. RAGHAV RAWAL.	DR. JAYAPRAKASH APPAJIGOL	“TO STUDY THE CORRELATION OF FERRITIN/TRANSFERRIN RATION WITH THE SEVERITY OF COVID-19 – A ONE YEAR CROSS SECTIONAL STUDY DONE IN KLES DR. PRABHAKAR KORE HOSPITAL AND MEDICAL RESEARCH CENTRE. BELAGAVI”
	DR. SUMA BORRA DHATRI	DR. DNYANESH MORKAR	“TO STUDY SERUM PHOSPHOLIPASE A2 IN SEPSIS AND NON SEPSIS PATIENTS AT KLE’S DR. PRABHAKAR KORE HOSPITAL & MRC, CROSS SECTIONAL ONE YEAR STUDY BELAGAVI”,
	DR. S PRIYANKA	DR. DNYANESH MORKAR	TO STUDY AST/ALT RATIO AS AN INDICATOR OF FUNCTIONAL SEVERITY IN CHRONIC HEART FAILURE WITH REDUCED LEFT VENTRICULAR EJECTION FRACTION AT DR PRABHAKAR KORE HOSPITAL AND MRC, BELAGAVI, ONE YEAR PROSPECTIVE CROSS SECTIONAL STUDY”
	DR. KRUTHIK.G.	DR. POURNIMA S PATIL	A CROSS SECTIONAL STUDY OF SLEEP PROBLEMS IN RHEUMATOID ARTHRITIS AND ITS IMPACT ON DISEASE ACTIVITY, PAIN PERCEPTION AND FUNCTIONAL DISABLITY”
	DR. MOHAMMAD SHAN ANSARI	DR. RAJU BANDAGER	“SIGNIFICANCE OF NEUTROPHIL TO RATIO AND PLATELET TO LYMPHOCYTE RATIO FOR PREDICTING CLINICAL OUTCOME AND SEVERITY IN COVID 19 PATIENTS ADMITTED IN DR. PRABHAKAR KORE HOSPITAL; KLE UNIVERSITY BELAGAVI”,
	DR. SPANDANA S	DR. RAJU BANDAGER Somannavar	“A STUDY ON INCIDENCE OF HYPONATREMIA IN PATIENTS WITH ACUTE ST ELEVATION MYOCARDIAL INFARCTION ADMITTED IN INTENSIVE CARDIAC CARE UNIT OF DR. PRABHAKAR KORE HOSPITAL;KLE UNIVERSITY BELAGAVI

Request a Quote

• Hon’ble Chancellor
• Vice Chancellor
• Vice Principal
• Medical Superintendent
• Biochemistry
• Forensic Medicine
• Microbiology
• Pharmacology
• Community Medicine
• Ophthalmology
• Obst & Gynecology
• Orthopaedics
• Skin & VD
• Pulmnonary Medicine
• Anaesthesiology
• Post Doctoral
• Endocrinology
• Department Public Health
• Research Unit
• Medical Education
• MCI Nodal Center
• Diploma Courses
• Department of Public Health
• Hospital Administration
• Govt-Approval
• KLE Dr. PBK Hospital & MRC
• KLE Dr.PBK Charitable Hospital
• PHC & UHC

An official website of the United States government

Here’s how you know

Official websites use .gov A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS A lock ( A locked padlock ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

• Heart-Healthy Living
• High Blood Pressure
• Sleep Apnea
• Information & Resources on COVID-19
• The Heart Truth®
• Learn More Breathe Better®
• Blood Diseases & Disorders Education Program
• Publications and Resources
• Clinical Trials
• Blood Disorders and Blood Safety
• Sleep Science and Sleep Disorders
• Lung Diseases
• Health Disparities and Inequities
• Heart and Vascular Diseases
• Precision Medicine Activities
• Obesity, Nutrition, and Physical Activity
• Population and Epidemiology Studies
• Women’s Health
• Research Topics
• All Science A-Z
• Grants and Training Home
• Policies and Guidelines
• Funding Opportunities and Contacts
• Training and Career Development
• Email Alerts
• NHLBI in the Press
• Research Features
• Ask a Scientist
• Past Events
• Upcoming Events
• Mission and Strategic Vision
• Divisions, Offices and Centers
• Advisory Committees
• Budget and Legislative Information
• Jobs and Working at the NHLBI
• Contact and FAQs
• NIH Sleep Research Plan
• News and Events
• < Back To All News

Experimental blood test predicts risk for developing COPD, other severe respiratory diseases

A scientific team supported by the National Institutes of Health (NIH) has created a preclinical blood test to identify adults most likely to develop severe respiratory conditions, including chronic obstructive pulmonary disease ( COPD ). The blood test analyzes 32 proteins that scientists determined accurately predicted an adult with an increased likelihood for requiring medical care for or dying from severe respiratory illness. The risk score was based on lung health data collected from nearly 2,500 U.S. adults over a 30-year period. The findings were published in the American Journal of Respiratory and Critical Care Medicine .

“We are still not ready for this test to be used in practice, but it’s a promising advance,” said James P. Kiley, Ph.D., director of the Division of Lung Diseases at NIH’s National Heart, Lung, and Blood Institute (NHLBI), which funded the study. “It consolidates insights from decades of breathing tests and medical evaluations into a single tool that has the potential to identify patients at risk for severe disease and complications.”

To create the risk score, investigators first reviewed lung health data collected from 2,470 adults, ages 18-30, who participated in a 30-year cardiovascular health study . They then screened thousands of proteins from blood samples provided by participants at the 25-year mark and selected 32 that best predicted which participants were having a rapid decline in lung function. These 32 proteins were then compiled in a score to predict how likely a person would either need medical treatment for or die from a lung condition or severe respiratory event.

Adults with higher scores had a 17% increased chance of requiring hospital care for respiratory illness, an 84% increased chance of developing COPD, and at least an 81% increased chance of dying from a respiratory disease, such as COPD or pneumonia. Adults with higher scores also had a 10% increased chance of experiencing respiratory exacerbations, such as a cough, mucus, or shortness of breath, that required treatment.

“Loss of lung function on a year-over-year basis is associated with poor respiratory health outcomes, but we do not have a good way to easily figure out if a patient is on a steep trajectory of lung function decline,” said Ravi Kalhan, M.D., a study coauthor and the Louis A. Simpson Professor of Pulmonary Medicine at the Northwestern University Feinberg School of Medicine, Chicago. “If we had an easy-to-implement clinical tool, like a blood test, that captured someone’s lung function trajectory at a single time point, it would enable earlier interventions which might, in the long run, improve lung health.”

Participants in the decades-long study took breathing tests to measure their lung function — up to six times throughout the study — and generated other lung health data. Throughout this period, 2,332 participants experienced a normal decline in lung function and 138 experienced a sharp decline.

To test the risk score, researchers used it to retrospectively assess respiratory disease risks in more than 40,000 adults from two earlier observational studies. The prediction model successfully identified adults who had the greatest chance of having severe respiratory conditions after multiple factors, including sex, race, body weight, asthma, and a history of smoking, were accounted for.

“Similar to using cholesterol levels to gauge a patient’s risk for having a heart attack, we’re looking at biological pathways to predict a person’s risk for having COPD or severe complications from COPD,” said Gabrielle Y. Liu, M.D., a study coauthor, pulmonologist, and an assistant professor of medicine at the University of California, Davis Medical Center in Sacramento.

This type of blood test still needs to be studied in clinical trials before being considered for approval by the Food and Drug Administration as a screening tool to help predict risks for chronic respiratory diseases . These conditions affect millions of adults worldwide and were the third-leading cause of death in 2019. Leading risk factors include smoking, air pollution, and exposure to chemicals or lung irritants, including gas, fumes, and dust, in the workplace.

Study: Liu G, Perry A, Washko G, et al. Proteomic risk score of increased respiratory susceptibility: a multi-cohort study. Am J Respir Crit Care Med . 2024; doi: 10.1164/rccm.202403-0613OC.

About the National Heart, Lung, and Blood Institute (NHLBI):  NHLBI is the global leader in conducting and supporting research in heart, lung, and blood diseases and sleep disorders that advances scientific knowledge, improves public health, and saves lives. For more information, visit  www.nhlbi.nih.gov .

About the National Institutes of Health (NIH):  NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit  www.nih.gov .

More Information

Related health topics, health education, related news.

• Alzheimer's disease & dementia
• Arthritis & Rheumatism
• Attention deficit disorders
• Autism spectrum disorders
• Biomedical technology
• Diseases, Conditions, Syndromes
• Endocrinology & Metabolism
• Gastroenterology
• Gerontology & Geriatrics
• Health informatics
• Inflammatory disorders
• Medical economics
• Medical research
• Medications
• Neuroscience
• Obstetrics & gynaecology
• Oncology & Cancer
• Ophthalmology
• Overweight & Obesity
• Parkinson's & Movement disorders
• Psychology & Psychiatry
• Radiology & Imaging
• Sleep disorders
• Sports medicine & Kinesiology
• Vaccination
• Breast cancer
• Cardiovascular disease
• Chronic obstructive pulmonary disease
• Colon cancer
• Coronary artery disease
• Heart attack
• Heart disease
• High blood pressure
• Kidney disease
• Lung cancer
• Multiple sclerosis
• Myocardial infarction
• Ovarian cancer
• Post traumatic stress disorder
• Rheumatoid arthritis
• Schizophrenia
• Skin cancer
• Type 2 diabetes
• Full List »

share this!

September 10, 2024

This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility:

fact-checked

peer-reviewed publication

trusted source

Experimental blood test predicts risk for developing COPD, other severe respiratory diseases

by NIH/National Heart, Lung and Blood Institute

A research team has created a preclinical blood test to identify adults most likely to develop severe respiratory conditions, including chronic obstructive pulmonary disease (COPD). The blood test analyzes 32 proteins that scientists determined accurately predicted an increased likelihood of requiring medical care or dying from severe respiratory illness.

The risk score was based on lung health data collected from nearly 2,500 U.S. adults over a 30-year period. The findings were published in the American Journal of Respiratory and Critical Care Medicine in a paper titled "Proteomic risk score of increased respiratory susceptibility: a multi-cohort study."

"We are still not ready for this test to be used in practice, but it's a promising advance," said James P. Kiley, Ph.D., director of the Division of Lung Diseases at the National Institutes of Health's National Heart, Lung, and Blood Institute (NHLBI). "It consolidates insights from decades of breathing tests and medical evaluations into a single tool that has the potential to identify patients at risk for severe disease and complications."

To create the risk score, investigators first reviewed lung health data collected from 2,470 adults, ages 18–30, who participated in a 30-year cardiovascular health study .

They then screened thousands of proteins from blood samples provided by participants at the 25-year mark and selected 32 that best predicted which participants were having a rapid decline in lung function. These 32 proteins were then compiled in a score to predict how likely a person would either need medical treatment for or die from a lung condition or severe respiratory event.

Adults with higher scores had a 17% increased chance of requiring hospital care for respiratory illness, an 84% increased chance of developing COPD, and at least an 81% increased chance of dying from a respiratory disease, such as COPD or pneumonia. Adults with higher scores also had a 10% increased chance of experiencing respiratory exacerbations, such as a cough, mucus, or shortness of breath, that required treatment.

"Loss of lung function on a year-over-year basis is associated with poor respiratory health outcomes, but we do not have a good way to easily figure out if a patient is on a steep trajectory of lung function decline," said Ravi Kalhan, M.D., a study co-author and the Louis A. Simpson Professor of Pulmonary Medicine at the Northwestern University Feinberg School of Medicine, Chicago.

"If we had an easy-to-implement clinical tool, like a blood test, that captured someone's lung function trajectory at a single time point, it would enable earlier interventions which might, in the long run, improve lung health."

Participants in the decades-long study took breathing tests to measure their lung function—up to six times throughout the study—and generated other lung health data. Throughout this period, 2,332 participants experienced a normal decline in lung function and 138 experienced a sharp decline.

To test the risk score , researchers used it to retrospectively assess respiratory disease risks in more than 40,000 adults from two earlier observational studies. The prediction model successfully identified adults who had the greatest chance of having severe respiratory conditions after multiple factors, including sex, race, body weight, asthma, and a history of smoking, were accounted for.

"Similar to using cholesterol levels to gauge a patient's risk for having a heart attack , we're looking at biological pathways to predict a person's risk for having COPD or severe complications from COPD," said Gabrielle Y. Liu, M.D., a study co-author, pulmonologist, and an assistant professor of medicine at the University of California, Davis Medical Center in Sacramento.

This type of blood test still needs to be studied in clinical trials before being considered for approval by the Food and Drug Administration as a screening tool to help predict risks for chronic respiratory diseases. These conditions affect millions of adults worldwide and were the third-leading cause of death in 2019. Leading risk factors include smoking, air pollution, and exposure to chemicals or lung irritants, including gas, fumes, and dust, in the workplace.

Explore further

Feedback to editors

Kids in families with too much screen time struggle with language skills, study suggests

4 hours ago

One dose of smallpox vaccine found to be moderately effective in preventing mpox infection

9 hours ago

Study shows shorter-course radiation better option for breast cancer patients than conventional schedule

Laughter may be as effective as drops for dry eye disease

New insights could help prevent psychosis relapses in youth and young adults

11 hours ago

New, rare type of small cell lung cancer identified

Can having a stroke change your sleep?

12 hours ago

Discovery of a new tumor cell type in childhood cancer

How the Parkinson's drug Levodopa causes psychiatric complications similar to drug abuse

Stress-induced events jumpstart sperm performance once the event has passed, research reveals

Related stories.

Genetics of COPD important for lung function in young people, study finds

Aug 13, 2024

Smoking + early menopause increases risk for lung disease, poor outcomes

Aug 1, 2024

New screening tool to help primary care physicians diagnose COPD

Feb 14, 2023

Study finds eliminating race-based metrics improves prediction for COPD outcomes

May 21, 2024

Lung abnormality progression linked to acute respiratory disease in smokers

Apr 30, 2024

Persistent respiratory issues in youth may decline lung function

Feb 4, 2018

Recommended for you

A new type of RNA could enhance vaccines and cancer treatments

13 hours ago

Research team develops the prosthesis of the future, the first in the world with magnetic control

14 hours ago

Wearable lung patch uses deep learning to detect asthma and COPD

15 hours ago

Exploring the frontiers of synaptic research with genetically encoded fluorescent tools

17 hours ago

Let us know if there is a problem with our content

Use this form if you have come across a typo, inaccuracy or would like to send an edit request for the content on this page. For general inquiries, please use our contact form . For general feedback, use the public comments section below (please adhere to guidelines ).

Please select the most appropriate category to facilitate processing of your request

Thank you for taking time to provide your feedback to the editors.

Your feedback is important to us. However, we do not guarantee individual replies due to the high volume of messages.

E-mail the story

Your email address is used only to let the recipient know who sent the email. Neither your address nor the recipient's address will be used for any other purpose. The information you enter will appear in your e-mail message and is not retained by Medical Xpress in any form.

Newsletter sign up

Get weekly and/or daily updates delivered to your inbox. You can unsubscribe at any time and we'll never share your details to third parties.

More information Privacy policy

Donate and enjoy an ad-free experience

We keep our content available to everyone. Consider supporting Science X's mission by getting a premium account.

E-mail newsletter